TY - CONF AU - Debora Gil AU - Oriol Ramos Terrades AU - Elisa Minchole AU - Carles Sanchez AU - Noelia Cubero de Frutos AU - Marta Diez-Ferrer AU - Rosa Maria Ortiz AU - Antoni Rosell A2 - CLIP PY - 2017// TI - Classification of Confocal Endomicroscopy Patterns for Diagnosis of Lung Cancer T2 - LNCS BT - 6th Workshop on Clinical Image-based Procedures: Translational Research in Medical Imaging SP - 151 EP - 159 VL - 10550 N2 - Confocal Laser Endomicroscopy (CLE) is an emerging imaging technique that allows the in-vivo acquisition of cell patterns of potentially malignant lesions. Such patterns could discriminate between inflammatory and neoplastic lesions and, thus, serve as a first in-vivo biopsy to discard cases that do not actually require a cell biopsy.The goal of this work is to explore whether CLE images obtained during videobronchoscopy contain enough visual information to discriminate between benign and malign peripheral lesions for lung cancer diagnosis. To do so, we have performed a pilot comparative study with 12 patients (6 adenocarcinoma and 6 benign-inflammatory) using 2 different methods for CLE pattern analysis: visual analysis by 3 experts and a novel methodology that uses graph methods to find patterns in pre-trained feature spaces. Our preliminary results indicate that although visual analysis can only achieve a 60.2% of accuracy, the accuracy of the proposed unsupervised image pattern classification raises to 84.6%.We conclude that CLE images visual information allow in-vivo detection of neoplastic lesions and graph structural analysis applied to deep-learning feature spaces can achieve competitive results. UR - https://link.springer.com/chapter/10.1007/978-3-319-67543-5_15 L1 - http://refbase.cvc.uab.es/files/GRM2017.pdf N1 - IAM; 600.096; 600.075; 600.145 ID - Debora Gil2017 ER -