PT Journal AU Mariella Dimiccoli Jean-Pascal Jacob Lionel Moisan TI Particle detection and tracking in fluorescence time-lapse imaging: a contrario approach SO Journal of Machine Vision and Applications JI MVAP PY 2016 BP 511 EP 527 VL 27 DE particle detection; particle tracking; a-contrario approach;  time-lapse fluorescence imaging AB In this work, we propose a probabilistic approach for the detection and thetracking of particles on biological images. In presence of very noised and poorquality data, particles and trajectories can be characterized by an a-contrariomodel, that estimates the probability of observing the structures of interestin random data. This approach, first introduced in the modeling of human visualperception and then successfully applied in many image processing tasks, leadsto algorithms that do not require a previous learning stage, nor a tediousparameter tuning and are very robust to noise. Comparative evaluations againsta well established baseline show that the proposed approach outperforms thestate of the art. ER