@Article{FredericSampedro2014, author="Frederic Sampedro and Sergio Escalera and Anna Domenech and Ignasi Carrio", title="A computational framework for cancer response assessment based on oncological PET-CT scans", journal="Computers in Biology and Medicine", year="2014", volume="55", pages="92--99", optkeywords="Computer aided diagnosis", optkeywords="Nuclear medicine", optkeywords="Machine learning", optkeywords="Image processing", optkeywords="Quantitative analysis", abstract="In this work we present a comprehensive computational framework to help in the clinical assessment of cancer response from a pair of time consecutive oncological PET-CT scans. In this scenario, the design and implementation of a supervised machine learning system to predict and quantify cancer progression or response conditions by introducing a novel feature set that models the underlying clinical context is described. Performance results in 100 clinical cases (corresponding to 200 whole body PET-CT scans) in comparing expert-based visual analysis and classifier decision making show up to 70\% accuracy within a completely automatic pipeline and 90\% accuracy when providing the system with expert-guided PET tumor segmentation masks.", optnote="HuPBA;MILAB", optnote="exported from refbase (http://refbase.cvc.uab.es/show.php?record=2606), last updated on Thu, 17 Nov 2016 11:38:32 +0100", doi="10.1016/j.compbiomed.2014.10.014" }