PT Journal AU C. Butakoff Simone Balocco F.M. Sukno C. Hoogendoorn C. Tobon-Gomez G. Avegliano A.F. Frangi TI Left-ventricular Epi- and Endocardium Extraction from 3D Ultrasound Images Using an Automatically Constructed 3D ASM SO Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization JI CMBBE PY 2016 BP 265 EP 280 VL 4 IS 5 DI 10.1080/21681163.2014.910703 DE ASM; cardiac segmentation; statistical model; shape model; 3D ultrasound AB In this paper, we propose an automatic method for constructing an active shape model (ASM) to segment the complete cardiac left ventricle in 3D ultrasound (3DUS) images, which avoids costly manual landmarking. The automatic construction of the ASM has already been addressed in the literature; however, the direct application of these methods to 3DUS is hampered by a high level of noise and artefacts. Therefore, we propose to construct the ASM by fusing the multidetector computed tomography data, to learn the shape, with the artificially generated 3DUS, in order to learn the neighbourhood of the boundaries. Our artificial images were generated by two approaches: a faster one that does not take into account the geometry of the transducer, and a more comprehensive one, implemented in Field II toolbox. The segmentation accuracy of our ASM was evaluated on 20 patients with left-ventricular asynchrony, demonstrating plausibility of the approach. ER