@Article{XavierCarrillo2011,
author="Xavier Carrillo
and E Fernandez-Nofrerias
and Francesco Ciompi
and O. Rodriguez-Leor
and Petia Radeva
and Neus Salvatella
and Oriol Pujol
and J. Mauri
and A. Bayes",
title="Changes in Radial Artery Volume Assessed Using Intravascular Ultrasound: A Comparison of Two Vasodilator Regimens in Transradial Coronary Intervention",
journal="Journal of Invasive Cardiology",
year="2011",
volume="23",
number="10",
pages="401--404",
optkeywords="radial",
optkeywords="vasodilator treatment",
optkeywords="percutaneous coronary intervention",
optkeywords="IVUS",
optkeywords="volumetric IVUS analysis",
abstract="OBJECTIVES:This study used intravascular ultrasound (IVUS) to evaluate radial artery volume changes after intraarterial administration of nitroglycerin and/or verapamil.BACKGROUND:Radial artery spasm, which is associated with radial artery size, is the main limitation of the transradial approach in percutaneous coronary interventions (PCI).METHODS:This prospective, randomized study compared the effect of two intra-arterial vasodilator regimens on radial artery volume: 0.2 mg of nitroglycerin plus 2.5 mg of verapamil (Group 1; n = 15) versus 2.5 mg of verapamil alone (Group 2; n = 15). Radial artery lumen volume was assessed using IVUS at two time points: at baseline (5 minutes after sheath insertion) and post-vasodilator (1 minute after drug administration). The luminal volume of the radial artery was computed using ECOC Random Fields (ECOC-RF), a technique used for automatic segmentation of luminal borders in longitudinal cut images from IVUS sequences.RESULTS:There was a significant increase in arterial lumen volume in both groups, with an increase from 451 {\textpm} 177 mm{\textthreesuperior} to 508 {\textpm} 192 mm{\textthreesuperior} (p = 0.001) in Group 1 and from 456 {\textpm} 188 mm{\textthreesuperior} to 509 {\textpm} 170 mm{\textthreesuperior} (p = 0.001) in Group 2. There were no significant differences between the groups in terms of absolute volume increase (58 mm{\textthreesuperior} versus 53 mm{\textthreesuperior}, respectively; p = 0.65) or in relative volume increase (14\% versus 20\%, respectively; p = 0.69).CONCLUSIONS:Administration of nitroglycerin plus verapamil or verapamil alone to the radial artery resulted in similar increases in arterial lumen volume according to ECOC-RF IVUS measurements.",
optnote="MILAB;HuPBA",
optnote="exported from refbase (http://refbase.cvc.uab.es/show.php?record=1797), last updated on Fri, 07 Mar 2014 17:11:20 +0100"
}