Abstract: Intravascular ultrasound (IVUS) represents a powerful imaging technique to explore coronary vessels and to study their morphology and histologic properties. In this paper, we characterize different tissues based on radial frequency, texture-based, and combined features. To deal with the classification of multiple tissues, we require the use of robust multi-class learning techniques. In this sense, error-correcting output codes (ECOC) show to robustly combine binary classifiers to solve multi-class problems. In this context, we propose a strategy to model multi-class classification tasks using sub-classes information in the ECOC framework. The new strategy splits the classes into different sub-sets according to the applied base classifier. Complex IVUS data sets containing overlapping data are learnt by splitting the original set of classes into sub-classes, and embedding the binary problems in a problem-dependent ECOC design. The method automatically characterizes different tissues, showing performance improvements over the state-of-the-art ECOC techniques for different base classifiers. Furthermore, the combination of RF and texture-based features also shows improvements over the state-of-the-art approaches.

Abstract: In this work we present a comprehensive computational framework to help in the clinical assessment of cancer response from a pair of time consecutive oncological PET-CT scans. In this scenario, the design and implementation of a supervised machine learning system to predict and quantify cancer progression or response conditions by introducing a novel feature set that models the underlying clinical context is described. Performance results in 100 clinical cases (corresponding to 200 whole body PET-CT scans) in comparing expert-based visual analysis and classifier decision making show up to 70% accuracy within a completely automatic pipeline and 90% accuracy when providing the system with expert-guided PET tumor segmentation masks.

Abstract: This paper introduces the use of single-layer and deep convolutional networks for remote sensing data analysis. Direct application to multi- and hyperspectral imagery of supervised (shallow or deep) convolutional networks is very challenging given the high input data dimensionality and the relatively small amount of available labeled data. Therefore, we propose the use of greedy layerwise unsupervised pretraining coupled with a highly efficient algorithm for unsupervised learning of sparse features. The algorithm is rooted on sparse representations and enforces both population and lifetime sparsity of the extracted features, simultaneously. We successfully illustrate the expressive power of the extracted representations in several scenarios: classification of aerial scenes, as well as land-use classification in very high resolution or land-cover classification from multi- and hyperspectral images. The proposed algorithm clearly outperforms standard principal component analysis (PCA) and its kernel counterpart (kPCA), as well as current state-of-the-art algorithms of aerial classification, while being extremely computationally efficient at learning representations of data. Results show that single-layer convolutional networks can extract powerful discriminative features only when the receptive field accounts for neighboring pixels and are preferred when the classification requires high resolution and detailed results. However, deep architectures significantly outperform single-layer variants, capturing increasing levels of abstraction and complexity throughout the feature hierarchy.