Esmitt Ramirez author Carles Sanchez author Agnes Borras author Marta Diez-Ferrer author Antoni Rosell author Debora Gil author 2018 Virtual bronchoscopy (VB) is a non-invasive exploration tool for intervention planning and navigation of possible pulmonary lesions (PLs). A VB software involves the location of a PL and the calculation of a route, starting from the trachea, to reach it. The selection of a VB software might be a complex process, and there is no consensus in the community of medical software developers in which is the best-suited system to use or framework to choose. The authors present Bronchoscopy Exploration (BronchoX), a VB software to plan biopsy interventions that generate physician-readable instructions to reach the PLs. The authors’ solution is open source, multiplatform, and extensible for future functionalities, designed by their multidisciplinary research and development group. BronchoX is a compound of different algorithms for segmentation, visualisation, and navigation of the respiratory tract. Performed results are a focus on the test the effectiveness of their proposal as an exploration software, also to measure its accuracy as a guiding system to reach PLs. Then, 40 different virtual planning paths were created to guide physicians until distal bronchioles. These results provide a functional software for BronchoX and demonstrate how following simple instructions is possible to reach distal lesions from the trachea. IAM; 600.096; 600.075; 601.323; 601.337; 600.145 exported from refbase (http://refbase.cvc.uab.es/show.php?record=3132), last updated on Tue, 25 Oct 2022 13:23:25 +0200 text https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222182/ http://refbase.cvc.uab.es/files/RSB2018a.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222182/ Admin @ si @ RSB2018a rank (SJR) author periodical academic journal 177–182