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Author Clementine Decamps; Alexis Arnaud; Florent Petitprez; Mira Ayadi; Aurelia Baures; Lucile Armenoult; Sergio Escalera; Isabelle Guyon; Remy Nicolle; Richard Tomasini; Aurelien de Reynies; Jerome Cros; Yuna Blum; Magali Richard
Title DECONbench: a benchmarking platform dedicated to deconvolution methods for tumor heterogeneity quantification Type Journal Article
Year 2021 Publication BMC Bioinformatics Abbreviated Journal
Volume 22 Issue Pages 473
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Abstract Quantification of tumor heterogeneity is essential to better understand cancer progression and to adapt therapeutic treatments to patient specificities. Bioinformatic tools to assess the different cell populations from single-omic datasets as bulk transcriptome or methylome samples have been recently developed, including reference-based and reference-free methods. Improved methods using multi-omic datasets are yet to be developed in the future and the community would need systematic tools to perform a comparative evaluation of these algorithms on controlled data.
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Notes HUPBA; no proj;MILAB Approved no
Call Number Admin @ si @ DAP2021 Serial 3650
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