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Author (up) Frederic Sampedro; Sergio Escalera; Anna Domenech; Ignasi Carrio edit  doi
  Title A computational framework for cancer response assessment based on oncological PET-CT scans Type Journal Article
  Year 2014 Publication Computers in Biology and Medicine Abbreviated Journal CBM  
  Volume 55 Issue Pages 92–99  
  Keywords Computer aided diagnosis; Nuclear medicine; Machine learning; Image processing; Quantitative analysis  
  Abstract In this work we present a comprehensive computational framework to help in the clinical assessment of cancer response from a pair of time consecutive oncological PET-CT scans. In this scenario, the design and implementation of a supervised machine learning system to predict and quantify cancer progression or response conditions by introducing a novel feature set that models the underlying clinical context is described. Performance results in 100 clinical cases (corresponding to 200 whole body PET-CT scans) in comparing expert-based visual analysis and classifier decision making show up to 70% accuracy within a completely automatic pipeline and 90% accuracy when providing the system with expert-guided PET tumor segmentation masks.  
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  Area Expedition Conference  
  Notes HuPBA;MILAB Approved no  
  Call Number Admin @ si @ SED2014 Serial 2606  
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