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Frederic Sampedro; Sergio Escalera; Anna Domenech; Ignasi Carrio |
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Title |
A computational framework for cancer response assessment based on oncological PET-CT scans |
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2014 |
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Computers in Biology and Medicine |
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CBM |
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55 |
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92–99 |
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Computer aided diagnosis; Nuclear medicine; Machine learning; Image processing; Quantitative analysis |
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In this work we present a comprehensive computational framework to help in the clinical assessment of cancer response from a pair of time consecutive oncological PET-CT scans. In this scenario, the design and implementation of a supervised machine learning system to predict and quantify cancer progression or response conditions by introducing a novel feature set that models the underlying clinical context is described. Performance results in 100 clinical cases (corresponding to 200 whole body PET-CT scans) in comparing expert-based visual analysis and classifier decision making show up to 70% accuracy within a completely automatic pipeline and 90% accuracy when providing the system with expert-guided PET tumor segmentation masks. |
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HuPBA;MILAB |
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no |
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Admin @ si @ SED2014 |
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2606 |
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Author |
Eloi Puertas; Sergio Escalera; Oriol Pujol |
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Title |
Generalized Multi-scale Stacked Sequential Learning for Multi-class Classification |
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Journal Article |
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2015 |
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Pattern Analysis and Applications |
Abbreviated Journal |
PAA |
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18 |
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2 |
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247-261 |
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Stacked sequential learning; Multi-scale; Error-correct output codes (ECOC); Contextual classification |
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In many classification problems, neighbor data labels have inherent sequential relationships. Sequential learning algorithms take benefit of these relationships in order to improve generalization. In this paper, we revise the multi-scale sequential learning approach (MSSL) for applying it in the multi-class case (MMSSL). We introduce the error-correcting output codesframework in the MSSL classifiers and propose a formulation for calculating confidence maps from the margins of the base classifiers. In addition, we propose a MMSSL compression approach which reduces the number of features in the extended data set without a loss in performance. The proposed methods are tested on several databases, showing significant performance improvement compared to classical approaches. |
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Springer-Verlag |
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1433-7541 |
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HuPBA;MILAB |
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Admin @ si @ PEP2013 |
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2251 |
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Author |
Mohammad Ali Bagheri; Qigang Gao; Sergio Escalera |
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Title |
Combining Local and Global Learners in the Pairwise Multiclass Classification |
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Year |
2015 |
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Pattern Analysis and Applications |
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PAA |
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18 |
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4 |
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845-860 |
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Multiclass classification; Pairwise approach; One-versus-one |
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Pairwise classification is a well-known class binarization technique that converts a multiclass problem into a number of two-class problems, one problem for each pair of classes. However, in the pairwise technique, nuisance votes of many irrelevant classifiers may result in a wrong class prediction. To overcome this problem, a simple, but efficient method is proposed and evaluated in this paper. The proposed method is based on excluding some classes and focusing on the most probable classes in the neighborhood space, named Local Crossing Off (LCO). This procedure is performed by employing a modified version of standard K-nearest neighbor and large margin nearest neighbor algorithms. The LCO method takes advantage of nearest neighbor classification algorithm because of its local learning behavior as well as the global behavior of powerful binary classifiers to discriminate between two classes. Combining these two properties in the proposed LCO technique will avoid the weaknesses of each method and will increase the efficiency of the whole classification system. On several benchmark datasets of varying size and difficulty, we found that the LCO approach leads to significant improvements using different base learners. The experimental results show that the proposed technique not only achieves better classification accuracy in comparison to other standard approaches, but also is computationally more efficient for tackling classification problems which have a relatively large number of target classes. |
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Springer London |
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1433-7541 |
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HuPBA;MILAB |
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Admin @ si @ BGE2014 |
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2441 |
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Author |
Victor Ponce; Sergio Escalera; Marc Perez; Oriol Janes; Xavier Baro |
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Title |
Non-Verbal Communication Analysis in Victim-Offender Mediations |
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Journal Article |
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Year |
2015 |
Publication |
Pattern Recognition Letters |
Abbreviated Journal |
PRL |
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67 |
Issue |
1 |
Pages |
19-27 |
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Victim–Offender Mediation; Multi-modal human behavior analysis; Face and gesture recognition; Social signal processing; Computer vision; Machine learning |
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We present a non-invasive ambient intelligence framework for the semi-automatic analysis of non-verbal communication applied to the restorative justice field. We propose the use of computer vision and social signal processing technologies in real scenarios of Victim–Offender Mediations, applying feature extraction techniques to multi-modal audio-RGB-depth data. We compute a set of behavioral indicators that define communicative cues from the fields of psychology and observational methodology. We test our methodology on data captured in real Victim–Offender Mediation sessions in Catalonia. We define the ground truth based on expert opinions when annotating the observed social responses. Using different state of the art binary classification approaches, our system achieves recognition accuracies of 86% when predicting satisfaction, and 79% when predicting both agreement and receptivity. Applying a regression strategy, we obtain a mean deviation for the predictions between 0.5 and 0.7 in the range [1–5] for the computed social signals. |
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HuPBA;MV;OR;MILAB |
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Admin @ si @ PEP2015 |
Serial |
2583 |
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Author |
Frederic Sampedro; Sergio Escalera; Anna Domenech; Ignasi Carrio |
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Title |
Automatic Tumor Volume Segmentation in Whole-Body PET/CT Scans: A Supervised Learning Approach Source |
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Journal Article |
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Year |
2015 |
Publication |
Journal of Medical Imaging and Health Informatics |
Abbreviated Journal |
JMIHI |
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5 |
Issue |
2 |
Pages |
192-201 |
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CONTEXTUAL CLASSIFICATION; PET/CT; SUPERVISED LEARNING; TUMOR SEGMENTATION; WHOLE BODY |
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Whole-body 3D PET/CT tumoral volume segmentation provides relevant diagnostic and prognostic information in clinical oncology and nuclear medicine. Carrying out this procedure manually by a medical expert is time consuming and suffers from inter- and intra-observer variabilities. In this paper, a completely automatic approach to this task is presented. First, the problem is stated and described both in clinical and technological terms. Then, a novel supervised learning segmentation framework is introduced. The segmentation by learning approach is defined within a Cascade of Adaboost classifiers and a 3D contextual proposal of Multiscale Stacked Sequential Learning. Segmentation accuracy results on 200 Breast Cancer whole body PET/CT volumes show mean 49% sensitivity, 99.993% specificity and 39% Jaccard overlap Index, which represent good performance results both at the clinical and technological level. |
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HuPBA;MILAB |
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Admin @ si @ SED2015 |
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2584 |
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