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Tadashi Araki; Nobutaka Ikeda; Nilanjan Dey; Sayan Chakraborty; Luca Saba; Dinesh Kumar; Elisa Cuadrado Godia; Xiaoyi Jiang; Ajay Gupta; Petia Radeva; John R. Laird; Andrew Nicolaides; Jasjit S. Suri |
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A comparative approach of four different image registration techniques for quantitative assessment of coronary artery calcium lesions using intravascular ultrasound |
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2015 |
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Computer Methods and Programs in Biomedicine |
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CMPB |
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118 |
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2 |
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158-172 |
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MILAB |
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Admin @ si @ AID2015 |
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2640 |
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Frederic Sampedro; Sergio Escalera; Anna Domenech; Ignasi Carrio |
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A computational framework for cancer response assessment based on oncological PET-CT scans |
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2014 |
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Computers in Biology and Medicine |
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CBM |
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55 |
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92–99 |
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Computer aided diagnosis; Nuclear medicine; Machine learning; Image processing; Quantitative analysis |
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In this work we present a comprehensive computational framework to help in the clinical assessment of cancer response from a pair of time consecutive oncological PET-CT scans. In this scenario, the design and implementation of a supervised machine learning system to predict and quantify cancer progression or response conditions by introducing a novel feature set that models the underlying clinical context is described. Performance results in 100 clinical cases (corresponding to 200 whole body PET-CT scans) in comparing expert-based visual analysis and classifier decision making show up to 70% accuracy within a completely automatic pipeline and 90% accuracy when providing the system with expert-guided PET tumor segmentation masks. |
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HuPBA;MILAB |
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Admin @ si @ SED2014 |
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2606 |
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M. Oliver; G. Haro; Mariella Dimiccoli; B. Mazin; C. Ballester |
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A Computational Model for Amodal Completion |
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2016 |
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Journal of Mathematical Imaging and Vision |
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JMIV |
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56 |
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3 |
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511–534 |
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Perception; visual completion; disocclusion; Bayesian model;relatability; Euler elastica |
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This paper presents a computational model to recover the most likely interpretation
of the 3D scene structure from a planar image, where some objects may occlude others. The estimated scene interpretation is obtained by integrating some global and local cues and provides both the complete disoccluded objects that form the scene and their ordering according to depth.
Our method first computes several distal scenes which are compatible with the proximal planar image. To compute these different hypothesized scenes, we propose a perceptually inspired object disocclusion method, which works by minimizing the Euler's elastica as well as by incorporating the relatability of partially occluded contours and the convexity of the disoccluded objects. Then, to estimate the preferred scene we rely on a Bayesian model and define probabilities taking into account the global complexity of the objects in the hypothesized scenes as well as the effort of bringing these objects in their relative position in the planar image, which is also measured by an Euler's elastica-based quantity. The model is illustrated with numerical experiments on, both, synthetic and real images showing the ability of our model to reconstruct the occluded objects and the preferred perceptual order among them. We also present results on images of the Berkeley dataset with provided figure-ground ground-truth labeling. |
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MILAB; 601.235 |
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Admin @ si @ OHD2016b |
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2745 |
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Karim Lekadir; Alfiia Galimzianova; Angels Betriu; Maria del Mar Vila; Laura Igual; Daniel L. Rubin; Elvira Fernandez-Giraldez; Petia Radeva; Sandy Napel |
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A Convolutional Neural Network for Automatic Characterization of Plaque Composition in Carotid Ultrasound |
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2017 |
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IEEE Journal Biomedical and Health Informatics |
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J-BHI |
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21 |
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1 |
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48-55 |
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Characterization of carotid plaque composition, more specifically the amount of lipid core, fibrous tissue, and calcified tissue, is an important task for the identification of plaques that are prone to rupture, and thus for early risk estimation of cardiovascular and cerebrovascular events. Due to its low costs and wide availability, carotid ultrasound has the potential to become the modality of choice for plaque characterization in clinical practice. However, its significant image noise, coupled with the small size of the plaques and their complex appearance, makes it difficult for automated techniques to discriminate between the different plaque constituents. In this paper, we propose to address this challenging problem by exploiting the unique capabilities of the emerging deep learning framework. More specifically, and unlike existing works which require a priori definition of specific imaging features or thresholding values, we propose to build a convolutional neural network (CNN) that will automatically extract from the images the information that is optimal for the identification of the different plaque constituents. We used approximately 90 000 patches extracted from a database of images and corresponding expert plaque characterizations to train and to validate the proposed CNN. The results of cross-validation experiments show a correlation of about 0.90 with the clinical assessment for the estimation of lipid core, fibrous cap, and calcified tissue areas, indicating the potential of deep learning for the challenging task of automatic characterization of plaque composition in carotid ultrasound. |
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MILAB; no menciona |
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no |
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Admin @ si @ LGB2017 |
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2931 |
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Laura Igual; Joan Carles Soliva; Antonio Hernandez; Sergio Escalera; Xavier Jimenez ; Oscar Vilarroya; Petia Radeva |
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A fully-automatic caudate nucleus segmentation of brain MRI: Application in volumetric analysis of pediatric attention-deficit/hyperactivity disorder |
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2011 |
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BioMedical Engineering Online |
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BEO |
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10 |
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105 |
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1-23 |
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Brain caudate nucleus; segmentation; MRI; atlas-based strategy; Graph Cut framework |
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Background
Accurate automatic segmentation of the caudate nucleus in magnetic resonance images (MRI) of the brain is of great interest in the analysis of developmental disorders. Segmentation methods based on a single atlas or on multiple atlases have been shown to suitably localize caudate structure. However, the atlas prior information may not represent the structure of interest correctly. It may therefore be useful to introduce a more flexible technique for accurate segmentations.
Method
We present Cau-dateCut: a new fully-automatic method of segmenting the caudate nucleus in MRI. CaudateCut combines an atlas-based segmentation strategy with the Graph Cut energy-minimization framework. We adapt the Graph Cut model to make it suitable for segmenting small, low-contrast structures, such as the caudate nucleus, by defining new energy function data and boundary potentials. In particular, we exploit information concerning the intensity and geometry, and we add supervised energies based on contextual brain structures. Furthermore, we reinforce boundary detection using a new multi-scale edgeness measure.
Results
We apply the novel CaudateCut method to the segmentation of the caudate nucleus to a new set of 39 pediatric attention-deficit/hyperactivity disorder (ADHD) patients and 40 control children, as well as to a public database of 18 subjects. We evaluate the quality of the segmentation using several volumetric and voxel by voxel measures. Our results show improved performance in terms of segmentation compared to state-of-the-art approaches, obtaining a mean overlap of 80.75%. Moreover, we present a quantitative volumetric analysis of caudate abnormalities in pediatric ADHD, the results of which show strong correlation with expert manual analysis.
Conclusion
CaudateCut generates segmentation results that are comparable to gold-standard segmentations and which are reliable in the analysis of differentiating neuroanatomical abnormalities between healthy controls and pediatric ADHD. |
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1475-925X |
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MILAB;HuPBA |
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Admin @ si @ ISH2011 |
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1882 |
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