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Author |
Aura Hernandez-Sabate; Debora Gil; David Roche; Monica M. S. Matsumoto; Sergio S. Furuie |


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Title |
Inferring the Performance of Medical Imaging Algorithms |
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Conference Article |
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Year |
2011 |
Publication |
14th International Conference on Computer Analysis of Images and Patterns |
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Volume  |
6854 |
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520-528 |
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Keywords |
Validation, Statistical Inference, Medical Imaging Algorithms. |
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Abstract |
Evaluation of the performance and limitations of medical imaging algorithms is essential to estimate their impact in social, economic or clinical aspects. However, validation of medical imaging techniques is a challenging task due to the variety of imaging and clinical problems involved, as well as, the difficulties for systematically extracting a reliable solely ground truth. Although specific validation protocols are reported in any medical imaging paper, there are still two major concerns: definition of standardized methodologies transversal to all problems and generalization of conclusions to the whole clinical data set.
We claim that both issues would be fully solved if we had a statistical model relating ground truth and the output of computational imaging techniques. Such a statistical model could conclude to what extent the algorithm behaves like the ground truth from the analysis of a sampling of the validation data set. We present a statistical inference framework reporting the agreement and describing the relationship of two quantities. We show its transversality by applying it to validation of two different tasks: contour segmentation and landmark correspondence. |
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Sevilla |
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Springer-Verlag Berlin Heidelberg |
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Berlin |
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Pedro Real; Daniel Diaz-Pernil; Helena Molina-Abril; Ainhoa Berciano; Walter Kropatsch |
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CAIP |
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IAM; ADAS |
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IAM @ iam @ HGR2011 |
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1676 |
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Author |
Debora Gil; Aura Hernandez-Sabate; Mireia Burnat; Steven Jansen; Jordi Martinez-Vilalta |


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Title |
Structure-Preserving Smoothing of Biomedical Images |
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Conference Article |
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Year |
2009 |
Publication |
13th International Conference on Computer Analysis of Images and Patterns |
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Volume  |
5702 |
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427-434 |
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Keywords |
non-linear smoothing; differential geometry; anatomical structures segmentation; cardiac magnetic resonance; computerized tomography. |
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Abstract |
Smoothing of biomedical images should preserve gray-level transitions between adjacent tissues, while restoring contours consistent with anatomical structures. Anisotropic diffusion operators are based on image appearance discontinuities (either local or contextual) and might fail at weak inter-tissue transitions. Meanwhile, the output of block-wise and morphological operations is prone to present a block structure due to the shape and size of the considered pixel neighborhood. In this contribution, we use differential geometry concepts to define a diffusion operator that restricts to image consistent level-sets. In this manner, the final state is a non-uniform intensity image presenting homogeneous inter-tissue transitions along anatomical structures, while smoothing intra-structure texture. Experiments on different types of medical images (magnetic resonance, computerized tomography) illustrate its benefit on a further process (such as segmentation) of images. |
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Münster, Germany |
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Springer Berlin Heidelberg |
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LNCS |
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0302-9743 |
ISBN |
978-3-642-03766-5 |
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CAIP |
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IAM |
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IAM @ iam @ GHB2009 |
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1527 |
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Author |
Joel Barajas; Jaume Garcia; Karla Lizbeth Caballero; Francesc Carreras; Sandra Pujades; Petia Radeva |


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Title |
Correction of Misalignment Artifacts Among 2-D Cardiac MR Images in 3-D Space |
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Conference Article |
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Year |
2006 |
Publication |
1st International Wokshop on Computer Vision for Intravascular and Intracardiac Imaging (CVII’06) |
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Volume  |
3217 |
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114-121 |
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Cardiac Magnetic Resonance images offer the opportunity to study the heart in detail. One of the main issues in its modelling is to create an accurate 3-D reconstruction of the left ventricle from 2-D views. A first step to achieve this goal is the correct registration among the different image planes due to patient movements. In this article, we present an accurate method to correct displacement artifacts using the Normalized Mutual Information. Here, the image views are treated as planes in order to diminish the approximation error caused by the association of a certain thickness, and moved simultaneously to avoid any kind of bias in the alignment process. This method has been validated using real and syntectic plane displacements, yielding promising results. |
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Copenhagen (Denmark) |
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978-3-540-22977-3 |
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IAM;MILAB |
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IAM @ iam @ BGC2006 |
Serial |
1485 |
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Author |
Gloria Fernandez-Esparrach; Jorge Bernal; Cristina Rodriguez de Miguel; Debora Gil; Fernando Vilariño; Henry Cordova; Cristina Sanchez-Montes; Isis Ara |

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Title |
Utilidad de la visión por computador para la localización de pólipos pequeños y planos |
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Conference Article |
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Year |
2016 |
Publication |
XIX Reunión Nacional de la Asociación Española de Gastroenterología, Gastroenterology Hepatology |
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Volume  |
39 |
Issue |
2 |
Pages |
94 |
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Madrid (Spain) |
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AEGASTRO |
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MV; IAM; 600.097;SIAI |
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Admin @ si @FBR2016 |
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2779 |
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Author |
Aura Hernandez-Sabate; Monica Mitiko; Sergio Shiguemi; Debora Gil |


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Title |
A validation protocol for assessing cardiac phase retrieval in IntraVascular UltraSound |
Type |
Conference Article |
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Year |
2010 |
Publication |
Computing in Cardiology |
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37 |
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Pages |
899-902 |
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Abstract |
A good reliable approach to cardiac triggering is of utmost importance in obtaining accurate quantitative results of atherosclerotic plaque burden from the analysis of IntraVascular UltraSound. Although, in the last years, there has been an increase in research of methods for retrospective gating, there is no general consensus in a validation protocol. Many methods are based on quality assessment of longitudinal cuts appearance and those reporting quantitative numbers do not follow a standard protocol. Such heterogeneity in validation protocols makes faithful comparison across methods a difficult task. We propose a validation protocol based on the variability of the retrieved cardiac phase and explore the capability of several quality measures for quantifying such variability. An ideal detector, suitable for its application in clinical practice, should produce stable phases. That is, it should always sample the same cardiac cycle fraction. In this context, one should measure the variability (variance) of a candidate sampling with respect a ground truth (reference) sampling, since the variance would indicate how spread we are aiming a target. In order to quantify the deviation between the sampling and the ground truth, we have considered two quality scores reported in the literature: signed distance to the closest reference sample and distance to the right of each reference sample. We have also considered the residuals of the regression line of reference against candidate sampling. The performance of the measures has been explored on a set of synthetic samplings covering different cardiac cycle fractions and variabilities. From our simulations, we conclude that the metrics related to distances are sensitive to the shift considered while the residuals are robust against fraction and variabilities as far as one can establish a pair-wise correspondence between candidate and reference. We will further investigate the impact of false positive and negative detections in experimental data. |
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IEEE |
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0276-6547 |
ISBN |
978-1-4244-7318-2 |
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CINC |
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IAM; |
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no |
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IAM @ iam @ HSM2010 |
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1551 |
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Author |
Jaume Garcia; Debora Gil; A.Bajo; M.J.Ledesma-Carbayo; C.SantaMarta |


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Title |
Influence of the temporal resolution on the quantification of displacement fields in cardiac magnetic resonance tagged images |
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Conference Article |
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Year |
2008 |
Publication |
Proc. Computers in Cardiology |
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Volume  |
35 |
Issue |
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Pages |
785-788 |
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It is difficult to acquire tagged cardiac MR images with a high temporal and spatial resolution using clinical MR scanners. However, if such images are used for quantifying scores based on motion, it is essential a resolution as high as possible. This paper explores the influence of the temporal resolution of a tagged series on the quantification of myocardial dynamic parameters. To such purpose we have designed a SPAMM (Spatial Modulation of Magnetization) sequence allowing acquisition of sequences at simple and double temporal resolution. Sequences are processed to compute myocardial motion by an automatic technique based on the tracking of the harmonic phase of tagged images (the Harmonic Phase Flow, HPF). The results have been compared to manual tracking of myocardial tags. The error in displacement fields for double resolution sequences reduces 17%. |
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Alan Murray |
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IAM |
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Call Number |
IAM @ iam @ GGB2008 |
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1508 |
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Author |
Aura Hernandez-Sabate; Debora Gil; Josefina Mauri; Petia Radeva |

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Title |
Reducing cardiac motion in IVUS sequences |
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Conference Article |
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Year |
2006 |
Publication |
Proceeding of Computers in Cardiology |
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Volume  |
33 |
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Pages |
685-688 |
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Cardiac vessel displacement is a main artifact in IVUS sequences. It hinders visualization of the main structures in an appropriate orientation and alignment and affects extracting vessel measurements. In this paper, we present a novel approach for image sequence alignment based on spectral analysis, which removes rigid dynamics, preserving at the same time the vessel geometry. First, we suppress the translation by taking, for each frame, the center of mass of the image as origin of coordinates. In polar coordinates with such point as origin, the rotation appears as a horizontal displacement. The translation induces a phase shift in the Fourier coefficients of two consecutive polar images. We estimate the phase by adjusting a regression plane to the phases of the principal frequencies. Experiments show that the presented strategy suppress cardiac motion regardless of the acquisition device. 1. |
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IAM; MILAB |
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no |
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IAM @ iam @ HGM2006a |
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1554 |
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Author |
Jaume Garcia; Joel Barajas; Francesc Carreras; Sandra Pujades; Petia Radeva |


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Title |
An intuitive validation technique to compare local versus global tagged MRI analysis |
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Conference Article |
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Year |
2005 |
Publication |
Computers In Cardiology |
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32 |
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29–32 |
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Myocardium appears as a uniform tissue that seen in convectional Magnetic Resonance Images (MRI) shows just the contractile part of its movement. MR Tagging is a unique imaging technique that prints a grid over the tissue which moves according to the underlying movement of the myocardium revealing the true deformation of the cardiac muscle. Optical flow techniques based on spectral information estimate tissue displacement by analyzing information encoded in the phase maps which can be obtained using, local (Gabor) and global (HARP) methods. In this paper we compare both in synthetic and real Tagged MR sequences. We conclude that local method is slightly more accurate than the global one. On the other hand, global method is more efficient as it is much faster and less parameters have to be taken into account |
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Lyon (France) |
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0-7803-9337-6 |
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IAM;MILAB |
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IAM @ iam @ GBC2005 |
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639 |
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Author |
Aura Hernandez-Sabate; Debora Gil; Petia Radeva; E.N.Nofrerias |


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Title |
Anisotropic processing of image structures for adventitia detection in intravascular ultrasound images |
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Conference Article |
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2004 |
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Proc. Computers in Cardiology |
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31 |
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229-232 |
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The adventitia layer appears as a weak edge in IVUS images with a non-uniform grey level, which difficulties its detection. In order to enhance edges, we apply an anisotropic filter that homogenizes the grey level along the image significant structures (ridges, valleys and edges). A standard edge detector applied to the filtered image yields a set of candidate points prone to be unconnected. The final model is obtained by interpolating the former line segments along the tangent direction to the level curves of the filtered image with an anisotropic contour closing technique based on functional extension principles |
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Chicago (USA) |
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IAM; MILAB |
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IAM @ iam @ HGR2004 |
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1555 |
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Author |
Jaume Garcia; David Rotger; Francesc Carreras; R.Leta; Petia Radeva |


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Title |
Contrast echography segmentation and tracking by trained deformable models |
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Conference Article |
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Year |
2003 |
Publication |
Proc. Computers in Cardiology |
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30 |
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173-176 |
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The objective of this work is to segment the human left ventricle myocardium (LVM) in contrast echocardiography imaging and thus track it along a cardiac cycle in order to extract quantitative data about heart function. Ultrasound images are hard to work with due to their speckle appearance. To overcome this we report the combination of active contour models (ACM) or snakes and active shape models (ASM). The ability of ACM in giving closed and smooth curves in addition to the power of the ASM in producing shapes similar to the ones learned, evoke to a robust algorithm. Meanwhile the snake is attracted towards image main features, ASM acts as a correction factor. The algorithm was tested independently on 180 frames and satisfying results were obtained: in 95% the maximum difference between automatic and experts segmentation was less than 12 pixels. |
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Centre de Visió per Computador – Dept. Informàtica, UAB Edifici O – Campus UAB, 08193 Bellater |
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0276-6547 |
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0-7803-8170-X |
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IAM;MILAB |
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IAM @ iam @ GRC2003 |
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1512 |
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