toggle visibility Search & Display Options

Select All    Deselect All
 |   | 
Details
  Records Links
Author Sergio Vera edit  isbn
openurl 
  Title Anatomic Registration based on Medial Axis Parametrizations Type Book Whole
  Year 2015 Publication PhD Thesis, Universitat Autonoma de Barcelona-CVC Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract Image registration has been for many years the gold standard method to bring two images into correspondence. It has been used extensively in the eld of medical imaging in order to put images of di erent patients into a common overlapping spatial position. However, medical image registration is a slow, iterative optimization process, where many variables and prone to fall into the pit traps local minima.
A coordinate system parameterizing the interior of organs is a powerful tool for a systematic localization of injured tissue. If the same coordinate values are assigned to speci c anatomical sites, parameterizations ensure integration of data across different medical image modalities. Harmonic mappings have been used to produce parametric meshes over the surface of anatomical shapes, given their ability to set values at speci c locations through boundary conditions. However, most of the existing implementations in medical imaging restrict to either anatomical surfaces, or the depth coordinate with boundary conditions is given at discrete sites of limited geometric diversity.
The medial surface of the shape can be used to provide a continuous basis for the de nition of a depth coordinate. However, given that di erent methods for generation of medial surfaces generate di erent manifolds, not all of them are equally suited to be the basis of radial coordinate for a parameterization. It would be desirable that the medial surface will be smooth, and robust to surface shape noise, with low number of spurious branches or surfaces.
In this thesis we present methods for computation of smooth medial manifolds and apply them to the generation of for anatomical volumetric parameterization that extends current harmonic parameterizations to the interior anatomy using information provided by the volume medial surface. This reference system sets a solid base for creating anatomical models of the anatomical shapes, and allows comparing several patients in a common framework of reference.
 
  Address November 2015  
  Corporate Author Thesis Ph.D. thesis  
  Publisher Ediciones Graficas Rey Place of Publication Editor Debora Gil;Miguel Angel Gonzalez Ballester  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN (up) 978-84-943427-8-3 Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number Admin @ si @ Ver2015 Serial 2708  
Permanent link to this record
 

 
Author David Roche; Debora Gil; Jesus Giraldo edit  doi
isbn  openurl
  Title Mathematical modeling of G protein-coupled receptor function: What can we learn from empirical and mechanistic models? Type Book Chapter
  Year 2014 Publication G Protein-Coupled Receptors – Modeling and Simulation Advances in Experimental Medicine and Biology Abbreviated Journal  
  Volume 796 Issue 3 Pages 159-181  
  Keywords β-arrestin; biased agonism; curve fitting; empirical modeling; evolutionary algorithm; functional selectivity; G protein; GPCR; Hill coefficient; intrinsic efficacy; inverse agonism; mathematical modeling; mechanistic modeling; operational model; parameter optimization; receptor dimer; receptor oligomerization; receptor constitutive activity; signal transduction; two-state model  
  Abstract Empirical and mechanistic models differ in their approaches to the analysis of pharmacological effect. Whereas the parameters of the former are not physical constants those of the latter embody the nature, often complex, of biology. Empirical models are exclusively used for curve fitting, merely to characterize the shape of the E/[A] curves. Mechanistic models, on the contrary, enable the examination of mechanistic hypotheses by parameter simulation. Regretfully, the many parameters that mechanistic models may include can represent a great difficulty for curve fitting, representing, thus, a challenge for computational method development. In the present study some empirical and mechanistic models are shown and the connections, which may appear in a number of cases between them, are analyzed from the curves they yield. It may be concluded that systematic and careful curve shape analysis can be extremely useful for the understanding of receptor function, ligand classification and drug discovery, thus providing a common language for the communication between pharmacologists and medicinal chemists.  
  Address  
  Corporate Author Thesis  
  Publisher Springer Netherlands Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0065-2598 ISBN (up) 978-94-007-7422-3 Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number IAM @ iam @ RGG2014 Serial 2197  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate; Debora Gil edit   pdf
url  doi
isbn  openurl
  Title The Benefits of IVUS Dynamics for Retrieving Stable Models of Arteries Type Book Chapter
  Year 2012 Publication Intravascular Ultrasound Abbreviated Journal  
  Volume Issue Pages 185-206  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Intech Place of Publication Editor Yasuhiro Honda  
  Language English Summary Language english Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN (up) 978-953-307-900-4 Medium  
  Area Expedition Conference  
  Notes IAM; ADAS Approved no  
  Call Number IAM @ iam @ HeG2012 Serial 1684  
Permanent link to this record
 

 
Author Enric Marti; Jordi Regincos; Juan Jose Villanueva; Jaime Lopez-Krahe edit   pdf
isbn  openurl
  Title Line drawing interpretation as polyhedral objects to man-machine interaction in CAD systems Type Book Chapter
  Year 1994 Publication Advances in Pattern Recognition and Image Analysis, Abbreviated Journal  
  Volume Issue Pages 158-169  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher World Scientific Pub. Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN (up) 981-02-1872-9 Medium  
  Area Expedition Conference  
  Notes IAM;ISE Approved no  
  Call Number IAM @ iam @ MRL1994 Serial 1609  
Permanent link to this record
Select All    Deselect All
 |   | 
Details

Save Citations:
Export Records: