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Author Debora Gil; Jaume Garcia; Mariano Vazquez; Ruth Aris; Guilleaume Houzeaux edit   pdf
isbn  openurl
  Title Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function Type Conference Article
  Year 2008 Publication 8th World Congress on Computational Mechanichs (WCCM8) Abbreviated Journal  
  Volume Issue Pages  
  Keywords Left Ventricle, Electromechanical Models, Image Processing, Magnetic Resonance.  
  Abstract (up) Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models [1] consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality [2]. In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp [3].
We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment.
The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted.
The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have
Figure 1: Scheme for the Left Ventricle Patient-Sensitive Model.
computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model.
 
  Address Venice; Italy  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 9788496736559 Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ GGV2008b Serial 993  
Permanent link to this record
 

 
Author Debora Gil; Jaume Garcia; Manuel Vazquez; Ruth Aris; Guillaume Houzeaux edit   pdf
url  openurl
  Title Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function Type Conference Article
  Year 2008 Publication 8th World Congress on Computational Mechanichs (WCCM8)/5th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) Abbreviated Journal  
  Volume Issue Pages  
  Keywords Left Ventricle; Electromechanical Models; Image Processing; Magnetic Resonance.  
  Abstract (up) Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality . In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp. We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment. The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted. The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Venezia (Italia) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN B-31470-08 ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGV2008c Serial 1521  
Permanent link to this record
 

 
Author Elena Valderrama; Joan Oliver; Josep Maria-Basart; Enric Marti; Petia Radeva; Ricardo Toledo; R.Vilanova;F.Ced; J.Muñoz; S.Vacchina edit  openurl
  Title Convergencia al EEES de la ingeniería informática. Título de Grado en tecnología (Informática) Type Miscellaneous
  Year 2005 Publication I Jornades de Innovació Docent Abbreviated Journal  
  Volume Issue Pages  
  Keywords  
  Abstract (up) Elena Valderrama  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;RV;MILAB;ADAS Approved no  
  Call Number IAM @ iam @ VOB2005 Serial 1652  
Permanent link to this record
 

 
Author Jaume Garcia; Debora Gil; Francesc Carreras ; Sandra Pujades; R.Leta; Xavier Alomar; Guillem Pons-LLados edit   pdf
openurl 
  Title Un Model 3D del Ventricle Esquerre Integrant Anatomia i Funcionalitat Type Conference Article
  Year 2008 Publication XX Congrés de la Societat Catalana de Cardiologia, Actes del Congres Abbreviated Journal  
  Volume Issue Pages 122  
  Keywords  
  Abstract (up) Els canvis en la dinàmica del Ventricle Esquerre (VE) reflecteixen la majoria de malalties cardiovasculars . Els avenços en imatge mèdica han impulsat la recerca en models i simulacions de la dinàmica 3D del VE . La majoria dels models existents sols consideren l’anatomia externa del VE i no permeten una avaluació de l’acoblament electromecànic . Donat que la mecànica d’un muscle depèn de la orientació de les seves fibres, un model realista hauria d’incloure la disposició espacial de la banda ventricular helicoidal (BVH) .
Proposem desenvolupar un model del VE adaptat a cada pacient que integri, per primer cop, l’anatomia de la banda ventricular, l’anatomia externa del VE i la seva funcionalitat, per a una millor determinació del patró d’activació electromecànica
 
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Barcelona Editor  
  Language catalan Summary Language catalan Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ GGC2008c Serial 1504  
Permanent link to this record
 

 
Author David Roche; Debora Gil; Jesus Giraldo edit  doi
isbn  openurl
  Title Mathematical modeling of G protein-coupled receptor function: What can we learn from empirical and mechanistic models? Type Book Chapter
  Year 2014 Publication G Protein-Coupled Receptors – Modeling and Simulation Advances in Experimental Medicine and Biology Abbreviated Journal  
  Volume 796 Issue 3 Pages 159-181  
  Keywords β-arrestin; biased agonism; curve fitting; empirical modeling; evolutionary algorithm; functional selectivity; G protein; GPCR; Hill coefficient; intrinsic efficacy; inverse agonism; mathematical modeling; mechanistic modeling; operational model; parameter optimization; receptor dimer; receptor oligomerization; receptor constitutive activity; signal transduction; two-state model  
  Abstract (up) Empirical and mechanistic models differ in their approaches to the analysis of pharmacological effect. Whereas the parameters of the former are not physical constants those of the latter embody the nature, often complex, of biology. Empirical models are exclusively used for curve fitting, merely to characterize the shape of the E/[A] curves. Mechanistic models, on the contrary, enable the examination of mechanistic hypotheses by parameter simulation. Regretfully, the many parameters that mechanistic models may include can represent a great difficulty for curve fitting, representing, thus, a challenge for computational method development. In the present study some empirical and mechanistic models are shown and the connections, which may appear in a number of cases between them, are analyzed from the curves they yield. It may be concluded that systematic and careful curve shape analysis can be extremely useful for the understanding of receptor function, ligand classification and drug discovery, thus providing a common language for the communication between pharmacologists and medicinal chemists.  
  Address  
  Corporate Author Thesis  
  Publisher Springer Netherlands Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0065-2598 ISBN 978-94-007-7422-3 Medium  
  Area Expedition Conference  
  Notes IAM; 600.075 Approved no  
  Call Number IAM @ iam @ RGG2014 Serial 2197  
Permanent link to this record
 

 
Author Enric Marti; Debora Gil; Carme Julia edit   pdf
openurl 
  Title Una experiència en PBL per a la docència de Gràfics per Computador Type Miscellaneous
  Year 2005 Publication II Jornades d’innovació Docent Abbreviated Journal  
  Volume Issue Pages  
  Keywords Aprenentatge Basat en Projectes; Aprenentatge Basat en Problemes; Problem Based Learning; ECTS; EEES; Computer Graphics; OpenGL.  
  Abstract (up) En aquest article es presenta una experiència en ABP feta el curs 2004-05 en Gràfics per Computador 2, assignatura optativa de 3er curs d’Enginyeria Informàtica impartida a l’ETSE. En l’article s’explica l’organització docent abans d’ABP, basada en classes magistrals. Després es mostra l’organització en ABP i es quantifica en ECTS l’esforç de l’alumne en ambdues organitzacions. Essent conscient del diferent interès de l’alumnat per l’assignatura, se’ls hi ofereix dos itineraris: el de classes magistrals i d’ABP. Es mostren alguns resultats dels alumnes d’ABP i també les primeres enquestes realitzades als alumnes. S’exposen les conclusions en el primer any de l’experiència, plantejant temes de discussió. S’ha procurat que la proposta no desbordi l’esforç del professorat. Per això s’ofereix el doble itinerari, per a canalitzar per ABP els alumnes més interessats i permetre a la resta que realitzin el curs amb l’organització clàsica de l’assignatura: classes magistrals de teoria, problemes i pràctiques.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;ADAS; Approved no  
  Call Number IAM @ iam @ MGJ2005c Serial 1594  
Permanent link to this record
 

 
Author Enric Marti; Jaume Rocarias; Debora Gil; Marc Vivet; Carme Julia edit   pdf
isbn  openurl
  Title Uso de recursos virtuales en Aprendizaje Basado en Proyectos. Una experiencia en la asignatura de Graficos por Computador Type Miscellaneous
  Year 2008 Publication Octava Jornada sobre Aprendizaje Cooperativo Abbreviated Journal  
  Volume Issue Pages 79–88  
  Keywords  
  Abstract (up) En esta comunicación presentamos una experiencia en Aprendizaje Basado en Proyectos (Project
Based Learning – PBL) realizada los últimos cuatro años (cursos del 2004-05 al 2007-08) en Gráficos
por Computador 2, asignatura optativa de tercer curso de Ingeniería Informática, titulación impartida
en la Escuela Técnica Superior de Ingeniería (ETSE) de la Universidad Autónoma de Barcelona
(UAB).
Fruto de la constante voluntad de mejora de la organización ABP de nuestra asignatura nos decidimos
a utilizar una herramienta LMS (Learning Management System) basada en Moodle y adaptada por
nosotros llamada Caronte para poder gestionar la documentación generada en ABP, y añadir una
componente semipresencial a la asignatura.
En primer lugar se presenta la organización de nuestra asignatura, basada proponer al alumno dos
itinerarios para cursarla: el itinerario ABP y el itinerario basado en clases magistrales i examen que
llamaremos TPPE (Teoría, Problemas, Prácticas, Examen). La dinámica ABP nos genera una cantidad
importante de documentación entre los grupos y el profesor, aparte de el feedback que el profesor
genera a los alumnos.
En la segunda parte del artículo presentamos los espacios docentes electrónicos de ambos itinerarios,
con los que trabajan los alumnos.
Finalmente, mostramos los resultados obtenidos de alumnos matriculados y de encuestas de valoración
realizados por los alumnos para finalmente exponer las conclusiones de estos cuatro años de
experiencia en ABP y en el uso de recursos virtuales en ABP, así como plantear mejoras y temas de
discusión sobre ABP.
 
  Address Lleida  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-84-691-4605-7 Medium  
  Area Expedition Conference  
  Notes IAM;ADAS; Approved no  
  Call Number IAM @ iam @ MRG2008a Serial 1101  
Permanent link to this record
 

 
Author Enric Marti; Jaume Rocarias; Ricardo Toledo; Aura Hernandez-Sabate edit   pdf
isbn  openurl
  Title Caronte: plataforma Moodle con gestion flexible de grupos. Primeras experiencias en asignaturas de Ingenieria Informatica Type Miscellaneous
  Year 2009 Publication 15th Jornadas de Enseñanza Universitaria de la Informatica Abbreviated Journal  
  Volume Issue Pages 461–468  
  Keywords  
  Abstract (up) En este artículo se presenta Caronte, entorno LMS (Learning Management System) basado en Moodle. Una característica importante del entorno es la gestión flexible de grupos en una asignatura. Entendemos por grupo un conjunto de alumnos que realizan un trabajo y uno de ellos entrega la actividad propuesta (práctica, encuesta, etc.) en representación del grupo. Hemos trabajado en la confección de estos grupos, implementando un sistema de inscripción por contraseña.
Caronte ofrece un conjunto de actividades basadas en este concepto de grupo: encuestas, tareas (entrega de trabajos o prácticas), encuestas de autoevaluación y cuestionarios, entre otras.
Basada en nuestra actividad de encuesta, hemos definido una actividad de Control, que permite un cierto feedback electrónico del profesor sobre la actividad de los alumnos.
Finalmente, se presenta un resumen de las experiencias de uso de Caronte sobre asignaturas de Ingeniería Informática en el curso 2007-08.
 
  Address Barcelona, Spain  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN 978-84-692-2758-9 Medium  
  Area Expedition Conference JENUI  
  Notes IAM;RV;ADAS Approved no  
  Call Number IAM @ iam @ MRT2009 Serial 1202  
Permanent link to this record
 

 
Author Enric Marti edit  openurl
  Title Análisis de elementos gráficos en documentos Type Report
  Year 1996 Publication CVC Technical Report Abbreviated Journal  
  Volume Issue 9 Pages  
  Keywords  
  Abstract (up) En este texto se presenta un estudio sobre las t’ecnicas y aplicaciones de an’alisis de documentos, y más concretamente abordando la problem’atica del an’alisis de de entidades gr’aficas. El ’area de an’alisis de documentos tiene como objetivo la interpretaci’on de documentos impresos sobre papel por m’etodos computacionales, para obtener una descripci’on con un alto nivel de abstracci’on, que permita su posterior tratamiento y archivo por m’etodos inform’aticos. Este objetivo, junto a los trabajos realizados hasta el momento, le otorgan a esta ’area un amplio ’ambito de aplicaciones para la manipulaci’on y archivo de documentos sobre papel, que puede llegar a significar un salto cualitativo importante (del papel al disco ’optico) en el uso de soportes de informaci’on, debido a las importantes prestaciones de acceso y capacidad de archivo que suponen los medios inform’aticos. Generalmente los documentos son introducidos en los sistemas de an’alisis de documentos mediante scanner, obt...  
  Address  
  Corporate Author Thesis  
  Publisher Computer Vision Centre Place of Publication CVC UAB Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ Mar1996 Serial 1587  
Permanent link to this record
 

 
Author Enric Marti; Debora Gil; Marc Vivet ; Carme Julia edit   pdf
openurl 
  Title Balance de cuatro años de experiencia en la implantación de la metodología de Aprendizaje Basado en Proyectos en la asignatura de Gráficos por Computador en ingeniería Informática Type Miscellaneous
  Year 2008 Publication Actas V Jornadas Internacionales de Innovación Universitaria Abbreviated Journal  
  Volume Issue Pages  
  Keywords Aprendizaje cooperativo; aprendizaje basado en proyectos; experiencias docentes.  
  Abstract (up) En este trabajo se presentan los resultados de la aplicación de la metodología del aprendizaje cooperativo a la docencia de dos asignaturas de programación en ingeniería informática. ‘Algoritmos y programación’ y ‘Lenguajes de programación’ son dos asignaturas complementarias que se organizan entorno a un proyecto común que engloba los contenidos de ambas asignaturas. En la docencia de una parte muy importante de estas asignaturas, la metodología del aprendizaje cooperativo se ha adaptado a sus características específicas. Como muestra de esta adaptación presentamos dos ejemplos de las actividades desarrolladas dentro de la docencia de estas asignaturas. Después de tres años de aplicación, el análisis a nivel cualitativo y cuantitativo de los resultados muestra que éstos son muy satisfactorios y que la aplicación del método cooperativo ha mejorado de forma considerable el rendimiento de los alumnos en ambas asignaturas.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;ADAS Approved no  
  Call Number IAM @ iam @ MGV2008a Serial 1598  
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