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Author |
Debora Gil; Rosa Maria Ortiz; Carles Sanchez; Antoni Rosell |
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Title |
Objective endoscopic measurements of central airway stenosis. A pilot study |
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Journal Article |
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Year |
2018 |
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Respiration |
Abbreviated Journal |
RES |
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Volume |
95 |
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63–69 |
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Keywords |
Bronchoscopy; Tracheal stenosis; Airway stenosis; Computer-assisted analysis |
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Abstract  |
Endoscopic estimation of the degree of stenosis in central airway obstruction is subjective and highly variable. Objective: To determine the benefits of using SENSA (System for Endoscopic Stenosis Assessment), an image-based computational software, for obtaining objective stenosis index (SI) measurements among a group of expert bronchoscopists and general pulmonologists. Methods: A total of 7 expert bronchoscopists and 7 general pulmonologists were enrolled to validate SENSA usage. The SI obtained by the physicians and by SENSA were compared with a reference SI to set their precision in SI computation. We used SENSA to efficiently obtain this reference SI in 11 selected cases of benign stenosis. A Web platform with three user-friendly microtasks was designed to gather the data. The users had to visually estimate the SI from videos with and without contours of the normal and the obstructed area provided by SENSA. The users were able to modify the SENSA contours to define the reference SI using morphometric bronchoscopy. Results: Visual SI estimation accuracy was associated with neither bronchoscopic experience (p = 0.71) nor the contours of the normal and the obstructed area provided by the system (p = 0.13). The precision of the SI by SENSA was 97.7% (95% CI: 92.4-103.7), which is significantly better than the precision of the SI by visual estimation (p < 0.001), with an improvement by at least 15%. Conclusion: SENSA provides objective SI measurements with a precision of up to 99.5%, which can be calculated from any bronchoscope using an affordable scalable interface. Providing normal and obstructed contours on bronchoscopic videos does not improve physicians' visual estimation of the SI. |
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IAM; 600.075; 600.096; 600.145 |
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Admin @ si @ GOS2018 |
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3043 |
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Author |
Carles Sanchez |
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Title |
Tracheal ring detection in bronchoscopy |
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Report |
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2011 |
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CVC Technical Report |
Abbreviated Journal |
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Volume |
168 |
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Bronchoscopy, tracheal ring, segmentation |
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Abstract |
Endoscopy is the process in which a camera is introduced inside a human.
Given that endoscopy provides realistic images (in contrast to other modalities) and allows non-invase minimal intervention procedures (which can aid in diagnosis and surgical interventions), its use has spreaded during last decades.
In this project we will focus on bronchoscopic procedures, during which the camera is introduced through the trachea in order to have a diagnostic of the patient. The diagnostic interventions are focused on: degree of stenosis (reduction in tracheal area), prosthesis or early diagnosis of tumors. In the first case, assessment of the luminal area and the calculation of the diameters of the tracheal rings are required. A main limitation is that all the process is done by hand,
which means that the doctor takes all the measurements and decisions just by looking at the screen. As far as we know there is no computational framework for helping the doctors in the diagnosis.
This project will consist of analysing bronchoscopic videos in order to extract useful information for the diagnostic of the degree of stenosis. In particular we will focus on segmentation of the tracheal rings. As a result of this project several strategies (for detecting tracheal rings) had been implemented in order to compare their performance. |
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Master's thesis |
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Debora Gil, F.Javier Sanchez |
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english |
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english |
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IAM;MV |
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IAM @ iam @ San2011 |
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1841 |
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Aura Hernandez-Sabate; Debora Gil; Albert Teis |
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Title |
How Do Conservation Laws Define a Motion Suppression Score in In-Vivo Ivus Sequences? |
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Conference Article |
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2007 |
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Proc. IEEE Ultrasonics Symp |
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2231-2234 |
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validation standards; IVUS motion compensation; conservation laws. |
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Evaluation of arterial tissue biomechanics for diagnosis and treatment of cardiovascular diseases is an active research field in the biomedical imaging processing area. IntraVascular UltraSound (IVUS) is a unique tool for such assessment since it reflects tissue morphology and deformation. A proper quantification and visualization of both properties is hindered by vessel structures misalignments introduced by cardiac dynamics. This has encouraged development of IVUS motion compensation techniques. However, there is a lack of an objective evaluation of motion reduction ensuring a reliable clinical application This work reports a novel score, the Conservation of Density Rate (CDR), for validation of motion compensation in in-vivo pullbacks. Synthetic experiments validate the proposed score as measure of motion parameters accuracy; while results in in vivo pullbacks show its reliability in clinical cases. |
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IAM |
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IAM @ iam @ HTG2007 |
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1550 |
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Author |
Aura Hernandez-Sabate; Debora Gil; David Roche; Monica M. S. Matsumoto; Sergio S. Furuie |
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Title |
Inferring the Performance of Medical Imaging Algorithms |
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Conference Article |
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Year |
2011 |
Publication |
14th International Conference on Computer Analysis of Images and Patterns |
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6854 |
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520-528 |
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Validation, Statistical Inference, Medical Imaging Algorithms. |
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Evaluation of the performance and limitations of medical imaging algorithms is essential to estimate their impact in social, economic or clinical aspects. However, validation of medical imaging techniques is a challenging task due to the variety of imaging and clinical problems involved, as well as, the difficulties for systematically extracting a reliable solely ground truth. Although specific validation protocols are reported in any medical imaging paper, there are still two major concerns: definition of standardized methodologies transversal to all problems and generalization of conclusions to the whole clinical data set.
We claim that both issues would be fully solved if we had a statistical model relating ground truth and the output of computational imaging techniques. Such a statistical model could conclude to what extent the algorithm behaves like the ground truth from the analysis of a sampling of the validation data set. We present a statistical inference framework reporting the agreement and describing the relationship of two quantities. We show its transversality by applying it to validation of two different tasks: contour segmentation and landmark correspondence. |
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Sevilla |
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Springer-Verlag Berlin Heidelberg |
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Berlin |
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Pedro Real; Daniel Diaz-Pernil; Helena Molina-Abril; Ainhoa Berciano; Walter Kropatsch |
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LNCS |
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CAIP |
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IAM; ADAS |
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IAM @ iam @ HGR2011 |
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1676 |
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Author |
Ferran Poveda; Debora Gil;Enric Marti |
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Title |
Multi-resolution DT-MRI cardiac tractography |
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Conference Article |
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2012 |
Publication |
Statistical Atlases And Computational Models Of The Heart: Imaging and Modelling Challenges |
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7746 |
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270-277 |
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Even using objective measures from DT-MRI no consensus about myocardial architecture has been achieved so far. Streamlining provides good reconstructions at low level of detail, but falls short to give global abstract interpretations. In this paper, we present a multi-resolution methodology that is able to produce simplified representations of cardiac architecture. Our approach produces a reduced set of tracts that are representative of the main geometric features of myocardial anatomical structure. Experiments show that fiber geometry is preserved along reductions, which validates the simplified model for interpretation of cardiac architecture. |
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Nice, France |
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Springer Berlin Heidelberg |
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LNCS |
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0302-9743 |
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978-3-642-36960-5 |
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STACOM |
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IAM |
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IAM @ iam @ PGM2012 |
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1986 |
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Author |
Fernando Vilariño; Debora Gil; Petia Radeva |
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Title |
A Novel FLDA Formulation for Numerical Stability Analysis |
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Book Chapter |
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2004 |
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Recent Advances in Artificial Intelligence Research and Development |
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113 |
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77-84 |
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Supervised Learning; Linear Discriminant Analysis; Numerical Stability; Computer Vision |
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Fisher Linear Discriminant Analysis (FLDA) is one of the most popular techniques used in classification applying dimensional reduction. The numerical scheme involves the inversion of the within-class scatter matrix, which makes FLDA potentially ill-conditioned when it becomes singular. In this paper we present a novel explicit formulation of FLDA in terms of the eccentricity ratio and eigenvector orientations of the within-class scatter matrix. An analysis of this function will characterize those situations where FLDA response is not reliable because of numerical instability. This can solve common situations of poor classification performance in computer vision. |
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IOS Press |
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J. Vitrià, P. Radeva and I. Aguiló |
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978-1-58603-466-5 |
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MV;IAM;MILAB |
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IAM @ iam @ VGR2004 |
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1663 |
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Debora Gil; Katerine Diaz; Carles Sanchez; Aura Hernandez-Sabate |
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Title |
Early Screening of SARS-CoV-2 by Intelligent Analysis of X-Ray Images |
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Miscellaneous |
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2020 |
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Arxiv |
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Future SARS-CoV-2 virus outbreak COVID-XX might possibly occur during the next years. However the pathology in humans is so recent that many clinical aspects, like early detection of complications, side effects after recovery or early screening, are currently unknown. In spite of the number of cases of COVID-19, its rapid spread putting many sanitary systems in the edge of collapse has hindered proper collection and analysis of the data related to COVID-19 clinical aspects. We describe an interdisciplinary initiative that integrates clinical research, with image diagnostics and the use of new technologies such as artificial intelligence and radiomics with the aim of clarifying some of SARS-CoV-2 open questions. The whole initiative addresses 3 main points: 1) collection of standardize data including images, clinical data and analytics; 2) COVID-19 screening for its early diagnosis at primary care centers; 3) define radiomic signatures of COVID-19 evolution and associated pathologies for the early treatment of complications. In particular, in this paper we present a general overview of the project, the experimental design and first results of X-ray COVID-19 detection using a classic approach based on HoG and feature selection. Our experiments include a comparison to some recent methods for COVID-19 screening in X-Ray and an exploratory analysis of the feasibility of X-Ray COVID-19 screening. Results show that classic approaches can outperform deep-learning methods in this experimental setting, indicate the feasibility of early COVID-19 screening and that non-COVID infiltration is the group of patients most similar to COVID-19 in terms of radiological description of X-ray. Therefore, an efficient COVID-19 screening should be complemented with other clinical data to better discriminate these cases. |
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IAM; 600.139; 600.145; 601.337 |
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Admin @ si @ GDS2020 |
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3474 |
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Author |
Ernest Valveny; Enric Marti |
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Title |
Hand-drawn symbol recognition in graphic documents using deformable template matching and a Bayesian framework |
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2000 |
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Proc. 15th Int Pattern Recognition Conf |
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2 |
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239-242 |
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Hand-drawn symbols can take many different and distorted shapes from their ideal representation. Then, very flexible methods are needed to be able to handle unconstrained drawings. We propose here to extend our previous work in hand-drawn symbol recognition based on a Bayesian framework and deformable template matching. This approach gets flexibility enough to fit distorted shapes in the drawing while keeping fidelity to the ideal shape of the symbol. In this work, we define the similarity measure between an image and a symbol based on the distance from every pixel in the image to the lines in the symbol. Matching is carried out using an implementation of the EM algorithm. Thus, we can improve recognition rates and computation time with respect to our previous formulation based on a simulated annealing algorithm. |
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0-7695-0750-6 |
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DAG;IAM; |
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IAM @ iam @ VAM2000 |
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1656 |
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Author |
Albert Andaluz |
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Title |
Harmonic Phase Flow: User's guide |
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Manual |
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2012 |
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CVC |
Abbreviated Journal |
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HPF is a plugin for the computation of clinical scores under Osirix.
This manual provides a basic guide for experienced clinical staff. Chapter 1 provides the theoretical background in which this plugin is based.
Next, in chapter 2 we provide basic instructions for installing and uninstalling this plugin. chapter 3we shows a step-by-step scenario to compute clinical scores from tagged-MRI images with HPF. Finally, in chapter 4 we provide a quick guide for plugin developers |
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Bellaterra, Barcelona (Spain) |
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Computer Vision Center |
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CVC |
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Barcelona |
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english |
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english |
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IAM |
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IAM @ iam @ And2012 |
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1863 |
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Angels Barbera; Ruth Marginet Flinch; Montserrat Martin; Jose L Mate; Albert Oriol; Fina Martinez-Soler; Tomas Santalucia; Pedro L. Fernandez |
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Title |
The Immunohistochemical Expression of Programmed Death Ligand 1 |
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Journal Article |
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2020 |
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Applied Immunohistochemistry & Molecular Morphology |
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AIMM |
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Humanized antibodies targeting programmed death receptor 1 (PD-1) or its ligand (PD-L1) have been approved for the treatment of different cancers. Some of these antibodies show a correlation between the tissue expression of PD-L1 and response. Evaluation of PD-L1 expression presents multiple challenges, but some preanalytical issues such as tissue fixation have been scarcely evaluated. With the hypothesis that immunohistochemical staining of PD-L1 may be impacted by the time of specimen fixation, we evaluated differences in its expression in tonsil samples exposed to predefined fixation times. Random nontumoral tonsillectomy specimens were blindly evaluated in tissue microarray slides after staining with SP142 and SP263 antibodies. With fixation times ranging from 12 to 72 hours, between 2.8% and 6.1% of the samples were considered to be suboptimally stained, with no differences between the 2 antibodies within these fixation times. A significantly higher proportion of samples exposed to a fixation time of 96 hours presented suboptimal immunostaining (15.6%, P<0.0001). In addition, suboptimally stained spots were 20.8% using SP142 and 10.4% using SP263 after 96 hours of fixation (P=0.046). In conclusion, the quality of staining for PD-L1 in tonsil samples decreased with overfixation of the specimen at times >72 hours. Samples exposed to formaldehyde for longer periods presented suboptimal results for both clones, but the SP142 antibody presented a significantly lower tolerance to formalin overexposure than SP263. These results indicate the relevance of a controlled preanalytical processing of samples and particularly the length of fixation of tumor specimens. |
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IAM; 600.139; 600.145 |
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Admin @ si @ BMM2020 |
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3470 |
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