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Author Aura Hernandez-Sabate edit   pdf
openurl 
  Title Automatic adventitia segmentation in IntraVascular UltraSound images Type Report
  Year 2005 Publication CVC Technical Report Abbreviated Journal  
  Volume Issue 85 Pages  
  Keywords  
  Abstract A usual tool in cardiac disease diagnosis is vessel plaque assessment by analysis of IVUS sequences. Manual detection of lumen-intima, intima-media and media-adventitia vessel borders is the main activity of physicians in the process of plaque quantification. Large variety in vessel border descriptors, as well as, shades, artifacts and blurred response due to ultrasound physical properties troubles automated media-adventitia segmentation. This experimental work presents a solution to such a complex problem. The process blends advanced anisotropic filtering operators and statistic classification techniques, achieving an efficient vessel border modelling strategy. First of all, we introduce the theoretic base of the method. After that, we show the steps of the algorithm, validating the method with statistics that show that the media-adventitia border detection achieves an accuracy in the range of inter-observer variability regardless of plaque nature, vessel geometry and incomplete vessel borders. Finally, we present a little Matlab application to the automatic media-adventitia border.  
  Address  
  Corporate Author Thesis Master's thesis  
  Publisher Place of Publication 08193 Bellaterra, Barcelona (Spain) Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ Her2005 Serial 1544  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate; Debora Gil;Eduard Fernandez-Nofrerias;Petia Radeva; Enric Marti edit   pdf
doi  openurl
  Title Approaching Artery Rigid Dynamics in IVUS Type Journal Article
  Year 2009 Publication IEEE Transactions on Medical Imaging Abbreviated Journal TMI  
  Volume 28 Issue 11 Pages 1670-1680  
  Keywords Fourier analysis; intravascular ultrasound (IVUS) dynamics; longitudinal motion; quality measures; tissue deformation.  
  Abstract Tissue biomechanical properties (like strain and stress) are playing an increasing role in diagnosis and long-term treatment of intravascular coronary diseases. Their assessment strongly relies on estimation of vessel wall deformation. Since intravascular ultrasound (IVUS) sequences allow visualizing vessel morphology and reflect its dynamics, this technique represents a useful tool for evaluation of tissue mechanical properties. Image misalignment introduced by vessel-catheter motion is a major artifact for a proper tracking of tissue deformation. In this work, we focus on compensating and assessing IVUS rigid in-plane motion due to heart beating. Motion parameters are computed by considering both the vessel geometry and its appearance in the image. Continuum mechanics laws serve to introduce a novel score measuring motion reduction in in vivo sequences. Synthetic experiments validate the proposed score as measure of motion parameters accuracy; whereas results in in vivo pullbacks show the reliability of the presented methodologies in clinical cases.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN 0278-0062 ISBN Medium  
  Area Expedition Conference  
  Notes IAM; MILAB Approved no  
  Call Number IAM @ iam @ HGF2009 Serial 1545  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate; Debora Gil; Jaume Garcia; Enric Marti edit   pdf
doi  openurl
  Title Image-based Cardiac Phase Retrieval in Intravascular Ultrasound Sequences Type Journal Article
  Year 2011 Publication IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control Abbreviated Journal T-UFFC  
  Volume 58 Issue 1 Pages 60-72  
  Keywords 3-D exploring; ECG; band-pass filter; cardiac motion; cardiac phase retrieval; coronary arteries; electrocardiogram signal; image intensity local mean evolution; image-based cardiac phase retrieval; in vivo pullbacks acquisition; intravascular ultrasound sequences; longitudinal motion; signal extrema; time 36 ms; band-pass filters; biomedical ultrasonics; cardiovascular system; electrocardiography; image motion analysis; image retrieval; image sequences; medical image processing; ultrasonic imaging  
  Abstract Longitudinal motion during in vivo pullbacks acquisition of intravascular ultrasound (IVUS) sequences is a major artifact for 3-D exploring of coronary arteries. Most current techniques are based on the electrocardiogram (ECG) signal to obtain a gated pullback without longitudinal motion by using specific hardware or the ECG signal itself. We present an image-based approach for cardiac phase retrieval from coronary IVUS sequences without an ECG signal. A signal reflecting cardiac motion is computed by exploring the image intensity local mean evolution. The signal is filtered by a band-pass filter centered at the main cardiac frequency. Phase is retrieved by computing signal extrema. The average frame processing time using our setup is 36 ms. Comparison to manually sampled sequences encourages a deeper study comparing them to ECG signals.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN 0885-3010 ISBN Medium  
  Area Expedition Conference  
  Notes IAM;ADAS Approved no  
  Call Number IAM @ iam @ HGG2011 Serial 1546  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate; Debora Gil; Petia Radeva edit   pdf
openurl 
  Title A Deterministic-Statistical Strategy for Adventitia Segmentation in IVUS images Type Report
  Year 2005 Publication CVC Technical Report Abbreviated Journal  
  Volume Issue 89 Pages  
  Keywords  
  Abstract A useful tool for some specific studies in cardiac disease diagnosis is vessel plaque assessment by analysis of IVUS sequences. Manual detection of luminal (inner) and media-adventitia (external) vessel borders is the main activity of physicians in the process of lumen narrowing (plaque) quantification. Difficult definition of vessel border descriptors, as well as, shades, artifacts and blurred signal response due to ultrasound physical properties troubles automated adventitia segmentation. In order to efficiently approach such a complex problem, we propose blending advanced anisotropic filtering operators and statistical classification techniques into a vessel border modelling strategy. Our systematic statistical analysis shows that the reported adventitia detection achieves an accuracy in the range of inter-observer variability regardless of plaque nature, vessel geometry and incomplete vessel borders.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; MILAB Approved no  
  Call Number IAM @ iam @ HGR2005a Serial 1548  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate; Debora Gil; Petia Radeva edit   pdf
openurl 
  Title On the usefulness of supervised learning for vessel border detection in IntraVascular Imaging Type Conference Article
  Year 2005 Publication Proceeding of the 2005 conference on Artificial Intelligence Research and Development Abbreviated Journal  
  Volume Issue Pages 67-74  
  Keywords classification; vessel border modelling; IVUS  
  Abstract IntraVascular UltraSound (IVUS) imaging is a useful tool in diagnosis of cardiac diseases since sequences completely show the morphology of coronary vessels. Vessel borders detection, especially the external adventitia layer, plays a central role in morphological measures and, thus, their segmentation feeds development of medical imaging techniques. Deterministic approaches fail to yield optimal results due to the large amount of IVUS artifacts and vessel borders descriptors. We propose using classification techniques to learn the set of descriptors and parameters that best detect vessel borders. Statistical hypothesis test on the error between automated detections and manually traced borders by 4 experts show that our detections keep within inter-observer variability.  
  Address  
  Corporate Author Thesis  
  Publisher IOS Press Place of Publication Amsterdam, The Netherlands Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ HGR2005c Serial 1549  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate; Debora Gil; Albert Teis edit   pdf
doi  openurl
  Title How Do Conservation Laws Define a Motion Suppression Score in In-Vivo Ivus Sequences? Type Conference Article
  Year 2007 Publication Proc. IEEE Ultrasonics Symp Abbreviated Journal  
  Volume Issue Pages 2231-2234  
  Keywords validation standards; IVUS motion compensation; conservation laws.  
  Abstract Evaluation of arterial tissue biomechanics for diagnosis and treatment of cardiovascular diseases is an active research field in the biomedical imaging processing area. IntraVascular UltraSound (IVUS) is a unique tool for such assessment since it reflects tissue morphology and deformation. A proper quantification and visualization of both properties is hindered by vessel structures misalignments introduced by cardiac dynamics. This has encouraged development of IVUS motion compensation techniques. However, there is a lack of an objective evaluation of motion reduction ensuring a reliable clinical application This work reports a novel score, the Conservation of Density Rate (CDR), for validation of motion compensation in in-vivo pullbacks. Synthetic experiments validate the proposed score as measure of motion parameters accuracy; while results in in vivo pullbacks show its reliability in clinical cases.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM Approved no  
  Call Number IAM @ iam @ HTG2007 Serial 1550  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate; Monica Mitiko; Sergio Shiguemi; Debora Gil edit   pdf
url  isbn
openurl 
  Title A validation protocol for assessing cardiac phase retrieval in IntraVascular UltraSound Type Conference Article
  Year 2010 Publication Computing in Cardiology Abbreviated Journal  
  Volume 37 Issue Pages 899-902  
  Keywords  
  Abstract A good reliable approach to cardiac triggering is of utmost importance in obtaining accurate quantitative results of atherosclerotic plaque burden from the analysis of IntraVascular UltraSound. Although, in the last years, there has been an increase in research of methods for retrospective gating, there is no general consensus in a validation protocol. Many methods are based on quality assessment of longitudinal cuts appearance and those reporting quantitative numbers do not follow a standard protocol. Such heterogeneity in validation protocols makes faithful comparison across methods a difficult task. We propose a validation protocol based on the variability of the retrieved cardiac phase and explore the capability of several quality measures for quantifying such variability. An ideal detector, suitable for its application in clinical practice, should produce stable phases. That is, it should always sample the same cardiac cycle fraction. In this context, one should measure the variability (variance) of a candidate sampling with respect a ground truth (reference) sampling, since the variance would indicate how spread we are aiming a target. In order to quantify the deviation between the sampling and the ground truth, we have considered two quality scores reported in the literature: signed distance to the closest reference sample and distance to the right of each reference sample. We have also considered the residuals of the regression line of reference against candidate sampling. The performance of the measures has been explored on a set of synthetic samplings covering different cardiac cycle fractions and variabilities. From our simulations, we conclude that the metrics related to distances are sensitive to the shift considered while the residuals are robust against fraction and variabilities as far as one can establish a pair-wise correspondence between candidate and reference. We will further investigate the impact of false positive and negative detections in experimental data.  
  Address  
  Corporate Author Thesis  
  Publisher IEEE Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN 0276-6547 ISBN 978-1-4244-7318-2 Medium  
  Area Expedition Conference CINC  
  Notes IAM; Approved no  
  Call Number IAM @ iam @ HSM2010 Serial 1551  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate; Petia Radeva; Antonio Tovar; Debora Gil edit   pdf
url  openurl
  Title Vessel structures alignment by spectral analysis of ivus sequences Type Conference Article
  Year 2006 Publication Proc. of CVII, MICCAI Workshop Abbreviated Journal  
  Volume Issue Pages 39-36  
  Keywords  
  Abstract Three-dimensional intravascular ultrasound (IVUS) allows to visualize and obtain volumetric measurements of coronary lesions through an exploration of the cross sections and longitudinal views of arteries. However, the visualization and subsequent morpho-geometric measurements in IVUS longitudinal cuts are subject to distortion caused by periodic image/vessel motion around the IVUS catheter. Usually, to overcome the image motion artifact ECG-gating and image-gated approaches are proposed, leading to slowing the pullback acquisition or disregarding part of IVUS data. In this paper, we argue that the image motion is due to 3-D vessel geometry as well as cardiac dynamics, and propose a dynamic model based on the tracking of an elliptical vessel approximation to recover the rigid transformation and align IVUS images without loosing any IVUS data. We report an extensive validation with synthetic simulated data and in vivo IVUS sequences of 30 patients achieving an average reduction of the image artifact of 97% in synthetic data and 79% in real-data. Our study shows that IVUS alignment improves longitudinal analysis of the IVUS data and is a necessary step towards accurate reconstruction and volumetric measurements of 3-D IVUS.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Copenhaguen (Denmark), Editor  
  Language Summary Language Original Title  
  Series Editor Series Title 1st International Wokshop on Computer Vision for Intravascular and Intracardiac Imaging (CVII’06) Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; MILAB Approved no  
  Call Number IAM @ iam @ HRT2006 Serial 1552  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate; David Rotger; Debora Gil edit   pdf
doi  openurl
  Title Image-based ECG sampling of IVUS sequences Type Conference Article
  Year 2008 Publication Proc. IEEE Ultrasonics Symp. IUS 2008 Abbreviated Journal  
  Volume Issue Pages 1330-1333  
  Keywords Longitudinal Motion; Image-based ECG-gating; Fourier analysis  
  Abstract Longitudinal motion artifacts in IntraVascular UltraSound (IVUS) sequences hinders a properly 3D reconstruction and vessel measurements. Most of current techniques base on the ECG signal to obtain a gated pullback without the longitudinal artifact by using a specific hardware or the ECG signal itself. The potential of IVUS images processing for phase retrieval still remains little explored. In this paper, we present a fast forward image-based algorithm to approach ECG sampling. Inspired on the fact that maximum and minimum lumen areas are related to end-systole and end-diastole, our cardiac phase retrieval is based on the analysis of tissue density of mass along the sequence. The comparison between automatic and manual phase retrieval (0.07 ± 0.07 mm. of error) encourages a deep validation contrasting with ECG signals.  
  Address Beijing (China)  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ HRG2008 Serial 1553  
Permanent link to this record
 

 
Author Aura Hernandez-Sabate; Debora Gil; Josefina Mauri; Petia Radeva edit   pdf
openurl 
  Title Reducing cardiac motion in IVUS sequences Type Conference Article
  Year 2006 Publication Proceeding of Computers in Cardiology Abbreviated Journal  
  Volume 33 Issue Pages 685-688  
  Keywords  
  Abstract Cardiac vessel displacement is a main artifact in IVUS sequences. It hinders visualization of the main structures in an appropriate orientation and alignment and affects extracting vessel measurements. In this paper, we present a novel approach for image sequence alignment based on spectral analysis, which removes rigid dynamics, preserving at the same time the vessel geometry. First, we suppress the translation by taking, for each frame, the center of mass of the image as origin of coordinates. In polar coordinates with such point as origin, the rotation appears as a horizontal displacement. The translation induces a phase shift in the Fourier coefficients of two consecutive polar images. We estimate the phase by adjusting a regression plane to the phases of the principal frequencies. Experiments show that the presented strategy suppress cardiac motion regardless of the acquisition device. 1.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN ISBN Medium  
  Area Expedition Conference  
  Notes IAM; MILAB Approved no  
  Call Number IAM @ iam @ HGM2006a Serial 1554  
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