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Author Debora Gil; Oriol Ramos Terrades; Raquel Perez edit   pdf
openurl 
  Title Topological Radiomics (TOPiomics): Early Detection of Genetic Abnormalities in Cancer Treatment Evolution Type Conference Article
  Year 2020 Publication Women in Geometry and Topology Abbreviated Journal  
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  Address Barcelona; September 2019  
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  Notes IAM; DAG; 600.139; 600.145; 600.121 Approved no  
  Call Number Admin @ si @ GRP2020 Serial 3473  
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Author Debora Gil; Katerine Diaz; Carles Sanchez; Aura Hernandez-Sabate edit   pdf
url  openurl
  Title Early Screening of SARS-CoV-2 by Intelligent Analysis of X-Ray Images Type Miscellaneous
  Year 2020 Publication Arxiv Abbreviated Journal  
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  Abstract Future SARS-CoV-2 virus outbreak COVID-XX might possibly occur during the next years. However the pathology in humans is so recent that many clinical aspects, like early detection of complications, side effects after recovery or early screening, are currently unknown. In spite of the number of cases of COVID-19, its rapid spread putting many sanitary systems in the edge of collapse has hindered proper collection and analysis of the data related to COVID-19 clinical aspects. We describe an interdisciplinary initiative that integrates clinical research, with image diagnostics and the use of new technologies such as artificial intelligence and radiomics with the aim of clarifying some of SARS-CoV-2 open questions. The whole initiative addresses 3 main points: 1) collection of standardize data including images, clinical data and analytics; 2) COVID-19 screening for its early diagnosis at primary care centers; 3) define radiomic signatures of COVID-19 evolution and associated pathologies for the early treatment of complications. In particular, in this paper we present a general overview of the project, the experimental design and first results of X-ray COVID-19 detection using a classic approach based on HoG and feature selection. Our experiments include a comparison to some recent methods for COVID-19 screening in X-Ray and an exploratory analysis of the feasibility of X-Ray COVID-19 screening. Results show that classic approaches can outperform deep-learning methods in this experimental setting, indicate the feasibility of early COVID-19 screening and that non-COVID infiltration is the group of patients most similar to COVID-19 in terms of radiological description of X-ray. Therefore, an efficient COVID-19 screening should be complemented with other clinical data to better discriminate these cases.  
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  Notes IAM; 600.139; 600.145; 601.337 Approved no  
  Call Number Admin @ si @ GDS2020 Serial 3474  
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Author Oriol Ramos Terrades; Albert Berenguel; Debora Gil edit   pdf
url  openurl
  Title A flexible outlier detector based on a topology given by graph communities Type Miscellaneous
  Year 2020 Publication Arxiv Abbreviated Journal  
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  Abstract Outlier, or anomaly, detection is essential for optimal performance of machine learning methods and statistical predictive models. It is not just a technical step in a data cleaning process but a key topic in many fields such as fraudulent document detection, in medical applications and assisted diagnosis systems or detecting security threats. In contrast to population-based methods, neighborhood based local approaches are simple flexible methods that have the potential to perform well in small sample size unbalanced problems. However, a main concern of local approaches is the impact that the computation of each sample neighborhood has on the method performance. Most approaches use a distance in the feature space to define a single neighborhood that requires careful selection of several parameters. This work presents a local approach based on a local measure of the heterogeneity of sample labels in the feature space considered as a topological manifold. Topology is computed using the communities of a weighted graph codifying mutual nearest neighbors in the feature space. This way, we provide with a set of multiple neighborhoods able to describe the structure of complex spaces without parameter fine tuning. The extensive experiments on real-world data sets show that our approach overall outperforms, both, local and global strategies in multi and single view settings.  
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  Notes IAM; DAG; 600.139; 600.145; 600.140; 600.121 Approved no  
  Call Number Admin @ si @ RBG2020 Serial 3475  
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Author Sonia Baeza; R.Domingo; M.Salcedo; G.Moragas; J.Deportos; I.Garcia Olive; Carles Sanchez; Debora Gil; Antoni Rosell edit  url
openurl 
  Title Artificial Intelligence to Optimize Pulmonary Embolism Diagnosis During Covid-19 Pandemic by Perfusion SPECT/CT, a Pilot Study Type Journal Article
  Year 2021 Publication American Journal of Respiratory and Critical Care Medicine Abbreviated Journal  
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  Notes IAM; 600.145 Approved no  
  Call Number Admin @ si @ BDS2021 Serial 3591  
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Author Mireia Sole; Joan Blanco; Debora Gil; Oliver Valero; B. Cardenas; G. Fonseka; E. Anton; Alvaro Pascual; Richard Frodsham; Zaida Sarrate edit  doi
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  Title Time to match; when do homologous chromosomes become closer? Type Journal Article
  Year 2022 Publication Chromosoma Abbreviated Journal CHRO  
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  Abstract In most eukaryotes, pairing of homologous chromosomes is an essential feature of meiosis that ensures homologous recombination and segregation. However, when the pairing process begins, it is still under investigation. Contrasting data exists in Mus musculus, since both leptotene DSB-dependent and preleptotene DSB-independent mechanisms have been described. To unravel this contention, we examined homologous pairing in pre-meiotic and meiotic Mus musculus cells using a threedimensional fuorescence in situ hybridization-based protocol, which enables the analysis of the entire karyotype using DNA painting probes. Our data establishes in an unambiguously manner that 73.83% of homologous chromosomes are already paired at premeiotic stages (spermatogonia-early preleptotene spermatocytes). The percentage of paired homologous chromosomes increases to 84.60% at mid-preleptotene-zygotene stage, reaching 100% at pachytene stage. Importantly, our results demonstrate a high percentage of homologous pairing observed before the onset of meiosis; this pairing does not occur randomly, as the percentage was higher than that observed in somatic cells (19.47%) and between nonhomologous chromosomes (41.1%). Finally, we have also observed that premeiotic homologous pairing is asynchronous and independent of the chromosome size, GC content, or presence of NOR regions.  
  Address August, 2022  
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  Notes IAM; 601.139; 600.145; 600.096 Approved no  
  Call Number Admin @ si @ SBG2022 Serial 3719  
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Author Guillermo Torres; Debora Gil; Antoni Rosell; S. Mena; Carles Sanchez edit  openurl
  Title Virtual Radiomics Biopsy for the Histological Diagnosis of Pulmonary Nodules – Intermediate Results of the RadioLung Project Type Journal Article
  Year 2023 Publication International Journal of Computer Assisted Radiology and Surgery Abbreviated Journal IJCARS  
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  Call Number Admin @ si @ TGM2023 Serial 3830  
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Author Juan Borrego-Carazo; Carles Sanchez; David Castells; Jordi Carrabina; Debora Gil edit  openurl
  Title A benchmark for the evaluation of computational methods for bronchoscopic navigation Type Journal Article
  Year 2022 Publication International Journal of Computer Assisted Radiology and Surgery Abbreviated Journal IJCARS  
  Volume 17 Issue 1 Pages (down)  
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  Call Number Admin @ si @ BSC2022 Serial 3832  
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Author Antoni Rosell; Sonia Baeza; S. Garcia-Reina; JL. Mate; Ignasi Guasch; I. Nogueira; I. Garcia-Olive; Guillermo Torres; Carles Sanchez; Debora Gil edit  openurl
  Title Radiomics to increase the effectiveness of lung cancer screening programs. Radiolung preliminary results. Type Journal Article
  Year 2022 Publication European Respiratory Journal Abbreviated Journal ERJ  
  Volume 60 Issue 66 Pages (down)  
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  Call Number Admin @ si @ RBG2022c Serial 3835  
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Author Guillermo Torres; Jan Rodríguez Dueñas; Sonia Baeza; Antoni Rosell; Carles Sanchez; Debora Gil edit   pdf
url  openurl
  Title Prediction of Malignancy in Lung Cancer using several strategies for the fusion of Multi-Channel Pyradiomics Images Type Conference Article
  Year 2023 Publication 7th Workshop on Digital Image Processing for Medical and Automotive Industry in the framework of SYNASC 2023 Abbreviated Journal  
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  Abstract This study shows the generation process and the subsequent study of the representation space obtained by extracting GLCM texture features from computer-aided tomography (CT) scans of pulmonary nodules (PN). For this, data from 92 patients from the Germans Trias i Pujol University Hospital were used. The workflow focuses on feature extraction using Pyradiomics and the VGG16 Convolutional Neural Network (CNN). The aim of the study is to assess whether the data obtained have a positive impact on the diagnosis of lung cancer (LC). To design a machine learning (ML) model training method that allows generalization, we train SVM and neural network (NN) models, evaluating diagnosis performance using metrics defined at slice and nodule level.  
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  Notes IAM Approved no  
  Call Number Admin @ si @ TRB2023 Serial 3926  
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Author Guillermo Torres; Debora Gil; Antoni Rosell; S. Mena; Carles Sanchez edit  openurl
  Title Virtual Radiomics Biopsy for the Histological Diagnosis of Pulmonary Nodules Type Conference Article
  Year 2023 Publication 37th International Congress and Exhibition is organized by Computer Assisted Radiology and Surgery Abbreviated Journal  
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  Address Munich; Germany; June 2023  
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  Area Expedition Conference CARS  
  Notes IAM Approved no  
  Call Number Admin @ si @ TGR2023a Serial 3950  
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