Abstract: In this thesis, several methods for the automatic analysis of Intravascular Ultrasound
(IVUS) sequences are presented, aimed at assisting physicians in the diagnosis, the assessment of the intervention and the monitoring of the patients with coronary disease.
The basis for the developed frameworks are machine learning, pattern recognition and
image processing techniques.
First, a novel approach for the automatic detection of vascular bifurcations in
IVUS is presented. The task is addressed as a binary classication problem (identifying bifurcation and non-bifurcation angular sectors in the sequence images). The
multiscale stacked sequential learning algorithm is applied, to take into account the
spatial and temporal context in IVUS sequences, and the results are rened using
a-priori information about branching dimensions and geometry. The achieved performance is comparable to intra- and inter-observer variability.
Then, we propose a novel method for the automatic non-rigid alignment of IVUS
sequences of the same patient, acquired at dierent moments (before and after percutaneous coronary intervention, or at baseline and follow-up examinations). The
method is based on the description of the morphological content of the vessel, obtained by extracting temporal morphological proles from the IVUS acquisitions, by
means of methods for segmentation, characterization and detection in IVUS. A technique for non-rigid sequence alignment – the Dynamic Time Warping algorithm -
is applied to the proles and adapted to the specic clinical problem. Two dierent robust strategies are proposed to address the partial overlapping between frames
of corresponding sequences, and a regularization term is introduced to compensate
for possible errors in the prole extraction. The benets of the proposed strategy
are demonstrated by extensive validation on synthetic and in-vivo data. The results
show the interest of the proposed non-linear alignment and the clinical value of the
method.
Finally, a novel automatic approach for the extraction of the luminal border in
IVUS images is presented. The method applies the multiscale stacked sequential
learning algorithm and extends it to 2-D+T, in a rst classication phase (the identi-
cation of lumen and non-lumen regions of the images), while an active contour model
is used in a second phase, to identify the lumen contour. The method is extended
to the longitudinal dimension of the sequences and it is validated on a challenging
data-set.

Abstract: Los métodos basados en subespacios son una herramienta muy utilizada en aplicaciones de visión por computador. Aquí se presentan y validan algunos algoritmos que hemos propuesto en este campo de investigación. El primer algoritmo está relacionado con una extensión del método de vectores comunes discriminantes con kernel, que reinterpreta el espacio nulo de la matriz de dispersión intra-clase del conjunto de entrenamiento para obtener las características discriminantes. Dentro de los métodos basados en subespacios existen diferentes tipos de entrenamiento. Uno de los más populares, pero no por ello uno de los más eficientes, es el aprendizaje por lotes. En este tipo de aprendizaje, todas las muestras del conjunto de entrenamiento tienen que estar disponibles desde el inicio. De este modo, cuando nuevas muestras se ponen a disposición del algoritmo, el sistema tiene que ser reentrenado de nuevo desde cero. Una alternativa a este tipo de entrenamiento es el aprendizaje incremental. Aquí­ se proponen diferentes algoritmos incrementales del método de vectores comunes discriminantes.

Abstract: Pedestrian Protection Systems (PPSs) are on-board systems aimed at detecting and tracking people in the surroundings of a vehicle in order to avoid potentially dangerous situations. These systems, together with other Advanced Driver Assistance Systems (ADAS) such as lane departure warning or adaptive cruise control, are one of the most promising ways to improve traffic safety. By the use of computer vision, cameras working either in the visible or infra-red spectra have been demonstrated as a reliable sensor to perform this task. Nevertheless, the variability of human’s appearance, not only in terms of clothing and sizes but also as a result of their dynamic shape, makes pedestrians one of the most complex classes even for computer vision. Moreover, the unstructured changing and unpredictable environment in which such on-board systems must work makes detection a difficult task to be carried out with the demanded robustness. In this brief, the state of the art in PPSs is introduced through the review of the most relevant papers of the last decade. A common computational architecture is presented as a framework to organize each method according to its main contribution. More than 300 papers are referenced, most of them addressing pedestrian detection and others corresponding to the descriptors (features), pedestrian models, and learning machines used. In addition, an overview of topics such as real-time aspects, systems benchmarking and future challenges of this research area are presented.

Abstract: There is a resurgence in the use of structural approaches in the usual object recognition and retrieval problem. Graph theory, in particular, graph matching plays a relevant role in that. Specifically, the detection of an object (or a part of that) in an image in terms of structural features can be formulated as a subgraph matching. Subgraph matching is a challenging task. Specially due to the presence of outliers most of the graph matching algorithms do not perform well in subgraph matching scenario. Also exact subgraph isomorphism has proven to be an NP-complete problem. So naturally, in graph matching community, there are lot of efforts addressing the problem of subgraph matching within suboptimal bound. Most of them work with approximate algorithms that try to get an inexact solution in estimated way. In addition, usual recognition must cope with distortion. Inexact graph matching consists in finding the best isomorphism under a similarity measure. Theoretically this thesis proposes algorithms for solving subgraph matching in an approximate and inexact way.
We consider the symbol spotting problem on graphical documents or line drawings from application point of view. This is a well known problem in the graphics recognition community. It can be further applied for indexing and classification of documents based on their contents. The structural nature of this kind of documents easily motivates one for giving a graph based representation. So the symbol spotting problem on graphical documents can be considered as a subgraph matching problem. The main challenges in this application domain is the noise and distortions that might come during the usage, digitalization and raster to vector conversion of those documents. Apart from that computer vision nowadays is not any more confined within a limited number of images. So dealing a huge number of images with graph based method is a further challenge.
In this thesis, on one hand, we have worked on efficient and robust graph representation to cope with the noise and distortions coming from documents. On the other hand, we have worked on different graph based methods and framework to solve the subgraph matching problem in a better approximated way, which can also deal with considerable number of images. Firstly, we propose a symbol spotting method by hashing serialized subgraphs. Graph serialization allows to create factorized substructures such as graph paths, which can be organized in hash tables depending on the structural similarities of the serialized subgraphs. The involvement of hashing techniques helps to reduce the search space substantially and speeds up the spotting procedure. Secondly, we introduce contextual similarities based on the walk based propagation on tensor product graph. These contextual similarities involve higher order information and more reliable than pairwise similarities. We use these higher order similarities to formulate subgraph matching as a node and edge selection problem in the tensor product graph. Thirdly, we propose near convex grouping to form near convex region adjacency graph which eliminates the limitations of traditional region adjacency graph representation for graphic recognition. Fourthly, we propose a hierarchical graph representation by simplifying/correcting the structural errors to create a hierarchical graph of the base graph. Later these hierarchical graph structures are matched with some graph matching methods. Apart from that, in this thesis we have provided an overall experimental comparison of all the methods and some of the state-of-the-art methods. Furthermore, some dataset models have also been proposed.

Abstract: Searching for text objects in real scene images is an open problem and a very active computer vision research area. A large number of methods have been proposed tackling the text search as extension of the ones from the document analysis field or inspired by general purpose object detection methods. However the general problem of object search in real scene images remains an extremely challenging problem due to the huge variability in object appearance. This thesis builds on top of the most recent findings in the visual attention literature presenting a novel computational model of eye guidance aiming to better describe text object search in real scene images.
First are presented the relevant state-of-the-art results from the visual attention literature regarding eye movements and visual search. Relevant models of attention are discussed and integrated with recent observations on the role of top-down constraints and the emerging need for a layered model of attention in which saliency is not the only factor guiding attention. Visual attention is then explained by the interaction of several modulating factors, such as objects, value, plans and saliency. Then we introduce our probabilistic formulation of attention deployment in real scene. The model is based on the rationale that oculomotor control depends on two interacting but distinct processes: an attentional process that assigns value to the sources of information and motor process that flexibly links information with action.
In such framework, the choice of where to look next is task-dependent and oriented to classes of objects embedded within pictures of complex scenes. The dependence on task is taken into account by exploiting the value and the reward of gazing at certain image patches or proto-objects that provide a sparse representation of the scene objects.
In the experimental section the model is tested in laboratory condition, comparing model simulations with data from eye tracking experiments. The comparison is qualitative in terms of observable scan paths and quantitative in terms of statistical similarity of gaze shift amplitude. Experiments are performed using eye tracking data from both a publicly available dataset of face and text and from newly performed eye-tracking experiments on a dataset of street view pictures containing text. The last part of this thesis is dedicated to study the extent to which the proposed model can account for human eye movements in a low constrained setting. We used a mobile eye tracking device and an ad-hoc developed methodology to compare model simulated eye data with the human eye data from mobile eye tracking recordings. Such setting allow to test the model in an incomplete visual information condition, reproducing a close to real-life search task.

Abstract: There are countless collections of historical documents in archives and libraries that contain plenty of valuable information for historians and researchers. The extraction of this information has become a central task among the Document Analysis researches and practitioners.
There is an increasing interest to digital preserve and provide access to these kind of documents. But only the digitalization is not enough for the researchers. The extraction and/or indexation of information of this documents has had an increased interest among researchers. In many cases, and in particular in historical manuscripts, the full transcription of these documents is extremely dicult due the inherent deciencies: poor physical preservation, dierent writing styles, obsolete languages, etc. Word spotting has become a popular an ecient alternative to full transcription. It inherently involves a high level of degradation in the images. The search of words is holistically
formulated as a visual search of a given query shape in a larger image, instead of recognising the input text and searching the query word with an ascii string comparison. But the performance of classical word spotting approaches depend on the degradation level of the images being unacceptable in many cases . In this thesis we have proposed a novel paradigm called contextual word spotting method that uses the contextual/semantic information to achieve acceptable results whereas classical word spotting does not reach. The contextual word spotting framework proposed in this thesis is a segmentation-based word spotting approach, so an ecient word segmentation is needed. Historical handwritten
documents present some common diculties that can increase the diculties the extraction of the words. We have proposed a line segmentation approach that formulates the problem as nding the central part path in the area between two consecutive lines. This is solved as a graph traversal problem. A path nding algorithm is used to nd the optimal path in a graph, previously computed, between the text lines. Once the text lines are extracted, words are localized inside the text lines using a word segmentation technique from the state of the
art. Classical word spotting approaches can be improved using the contextual information of the documents. We have introduced a new framework, oriented to handwritten documents that present a highly structure, to extract information making use of context. The framework is an ecient tool for semi-automatic transcription that uses the contextual information to achieve better results than classical word spotting approaches. The contextual information is
automatically discovered by recognizing repetitive structures and categorizing all the words according to semantic classes. The most frequent words in each semantic cluster are extracted and the same text is used to transcribe all them. The experimental results achieved in this thesis outperform classical word spotting approaches demonstrating the suitability of the proposed ensemble architecture for spotting words in historical handwritten documents using contextual information.

Abstract: Recent advances in endoscopic devices have increased their use for minimal invasive diagnostic and intervention procedures. Among all endoscopic modalities, bronchoscopy is one of the most frequent with around 261 millions of procedures per year. Although the use of bronchoscopy is spread among clinical facilities it presents some drawbacks, being the visual inspection for the assessment of anatomical measurements the most prevalent of them. In
particular, inaccuracies in the estimation of the degree of stenosis (the percentage of obstructed airway) decreases its diagnostic yield and might lead to erroneous treatments. An objective computation of tracheal stenosis in bronchoscopy videos would constitute a breakthrough for this non-invasive technique and a reduction in treatment cost.
This thesis settles the first steps towards on-line reliable extraction of anatomical information from videobronchoscopy for computation of objective measures. In particular, we focus on the computation of the degree of stenosis, which is obtained by comparing the area delimited by a healthy tracheal ring and the stenosed lumen. Reliable extraction of airway structures in interventional videobronchoscopy is a challenging task. This is mainly due to the large variety of acquisition conditions (positions and illumination), devices (different digitalizations) and in videos acquired at the operating room the unpredicted presence of surgical devices (such as probe ends). This thesis contributes to on-line stenosis assessment in several ways. We
propose a parametric strategy for the extraction of lumen and tracheal rings regions based on the characterization of their geometry and appearance that guide a deformable model. The geometric and appearance characterization is based on a physical model describing the way bronchoscopy images are obtained and includes local and global descriptions. In order to ensure a systematic applicability we present a statistical framework to select the optimal
parameters of our method. Experiments perform on the first public annotated database, show that the performance of our method is comparable to the one provided by clinicians and its computation time allows for a on-line implementation in the operating room.