Abstract: Chromosome territoriality is not random along the cell cycle and it is mainly governed by intrinsic chromosome factors and gene expression patterns. Conversely, very few studies have explored the factors that determine chromosome territoriality and its influencing factors during meiosis. In this study, we analysed chromosome positioning in murine spermatogenic cells using three-dimensionally fluorescence in situ hybridization-based methodology, which allows the analysis of the entire karyotype. The main objective of the study was to decipher chromosome positioning in a radial axis (all analysed germ-cell nuclei) and longitudinal axis (only spermatozoa) and to identify the chromosomal factors that regulate such an arrangement. Results demonstrated that the radial positioning of chromosomes during spermatogenesis was cell-type specific and influenced by chromosomal factors associated to gene activity. Chromosomes with specific features that enhance transcription (high GC content, high gene density and high numbers of predicted expressed genes) were preferentially observed in the inner part of the nucleus in virtually all cell types. Moreover, the position of the sex chromosomes was influenced by their transcriptional status, from the periphery of the nucleus when its activity was repressed (pachytene) to a more internal position when it is partially activated (spermatid). At pachytene, chromosome positioning was also influenced by chromosome size due to the bouquet formation. Longitudinal chromosome positioning in the sperm nucleus was not random either, suggesting the importance of ordered longitudinal positioning for the release and activation of the paternal genome after fertilisation.

Abstract: In this paper we propose the first deep unsupervised approach in human body reconstruction to estimate body surface from a sparse set of landmarks, so called DeepMurf. We apply a denoising autoencoder to estimate missing landmarks. Then we apply an attention model to estimate body joints from landmarks. Finally, a cascading network is applied to regress parameters of a statistical generative model that reconstructs body. Our set of proposed loss functions allows us to train the network in an unsupervised way. Results on four public datasets show that our approach accurately reconstructs the human body from real world mocap data.

Abstract: Deep video action recognition models have been highly successful in recent years but require large quantities of manually-annotated data, which are expensive and laborious to obtain. In this work, we investigate the generation of synthetic training data for video action recognition, as synthetic data have been successfully used to supervise models for a variety of other computer vision tasks. We propose an interpretable parametric generative model of human action videos that relies on procedural generation, physics models and other components of modern game engines. With this model we generate a diverse, realistic, and physically plausible dataset of human action videos, called PHAV for “Procedural Human Action Videos”. PHAV contains a total of 39,982 videos, with more than 1000 examples for each of 35 action categories. Our video generation approach is not limited to existing motion capture sequences: 14 of these 35 categories are procedurally-defined synthetic actions. In addition, each video is represented with 6 different data modalities, including RGB, optical flow and pixel-level semantic labels. These modalities are generated almost simultaneously using the Multiple Render Targets feature of modern GPUs. In order to leverage PHAV, we introduce a deep multi-task (i.e. that considers action classes from multiple datasets) representation learning architecture that is able to simultaneously learn from synthetic and real video datasets, even when their action categories differ. Our experiments on the UCF-101 and HMDB-51 benchmarks suggest that combining our large set of synthetic videos with small real-world datasets can boost recognition performance. Our approach also significantly outperforms video representations produced by fine-tuning state-of-the-art unsupervised generative models of videos.

Abstract: This paper addresses the problem of inferring unseen cross-modal image-to-image translations between multiple modalities. We assume that only some of the pairwise translations have been seen (i.e. trained) and infer the remaining unseen translations (where training pairs are not available). We propose mix and match networks, an approach where multiple encoders and decoders are aligned in such a way that the desired translation can be obtained by simply cascading the source encoder and the target decoder, even when they have not interacted during the training stage (i.e. unseen). The main challenge lies in the alignment of the latent representations at the bottlenecks of encoder-decoder pairs. We propose an architecture with several tools to encourage alignment, including autoencoders and robust side information and latent consistency losses. We show the benefits of our approach in terms of effectiveness and scalability compared with other pairwise image-to-image translation approaches. We also propose zero-pair cross-modal image translation, a challenging setting where the objective is inferring semantic segmentation from depth (and vice-versa) without explicit segmentation-depth pairs, and only from two (disjoint) segmentation-RGB and depth-RGB training sets. We observe that a certain part of the shared information between unseen modalities might not be reachable, so we further propose a variant that leverages pseudo-pairs which allows us to exploit this shared information between the unseen modalities

Abstract: This work presents and evaluates a novel compact scene representation based on Stixels that infers geometric and semantic information. Our approach overcomes the previous rather restrictive geometric assumptions for Stixels by introducing a novel depth model to account for non-flat roads and slanted objects. Both semantic and depth cues are used jointly to infer the scene representation in a sound global energy minimization formulation. Furthermore, a novel approximation scheme is introduced in order to significantly reduce the computational complexity of the Stixel algorithm, and then achieve real-time computation capabilities. The idea is to first perform an over-segmentation of the image, discarding the unlikely Stixel cuts, and apply the algorithm only on the remaining Stixel cuts. This work presents a novel over-segmentation strategy based on a fully convolutional network, which outperforms an approach based on using local extrema of the disparity map. We evaluate the proposed methods in terms of semantic and geometric accuracy as well as run-time on four publicly available benchmark datasets. Our approach maintains accuracy on flat road scene datasets while improving substantially on a novel non-flat road dataset.