Abstract: Image based human detection is of paramount interest for different applications. The most promising human detectors rely on discriminatively learnt classifiers, i.e., trained with labelled samples. However, labelling is a manual intensive task, especially in cases like human detection where it is necessary to provide at least bounding boxes framing the humans for training. To overcome such problem, in Marin et al. we have proposed the use of a virtual world where the labels of the different objects are obtained automatically. This means that the human models (classifiers) are learnt using the appearance of realistic computer graphics. Later, these models are used for human detection in images of the real world. The results of this technique are surprisingly good. However, these are not always as good as the classical approach of training and testing with data coming from the same camera and the same type of scenario. Accordingly, in Vazquez et al. we cast the problem as one of supervised domain adaptation. In doing so, we assume that a small amount of manually labelled samples from real-world images is required. To collect these labelled samples we use an active learning technique. Thus, ultimately our human model is learnt by the combination of virtual- and real-world labelled samples which, to the best of our knowledge, was not done before. Here, we term such combined space cool world. In this extended abstract we summarize our proposal, and include quantitative results from Vazquez et al. showing its validity.

Abstract: The operational model of agonism has been widely used for the analysis of agonist action since its formulation in 1983. The model includes the Em parameter, which is defined as the maximum response of the system. The methods for Em estimation provide Em values not significantly higher than the maximum responses achieved by full agonists. However, it has been found that that some classes of compounds as, for instance, superagonists and positive allosteric modulators can increase the full agonist maximum response, implying upper limits for Em and thereby posing doubts on the validity of Em estimates. Because of the correlation between Em and operational efficacy, τ, wrong Em estimates will yield wrong τ estimates.
In this presentation, the operational model of agonism and various methods for the simulation of allosteric modulation will be analyzed. Alternatives for curve fitting will be presented and discussed.

Abstract: We present different techniques to adapt a pedestrian classifier trained with synthetic images and the corresponding automatically generated annotations to operate with far infrared (FIR) images. The information contained in this kind of images allow us to develop a robust pedestrian detector invariant to extreme illumination changes.

Abstract: Training vision-based pedestrian detectors using synthetic datasets (virtual world) is a useful technique to collect automatically the training examples with their pixel-wise ground truth. However, as it is often the case, these detectors must operate in real-world images, experiencing a significant drop of their performance. In fact, this effect also occurs among different real-world datasets, i.e. detectors' accuracy drops when the training data (source domain) and the application scenario (target domain) have inherent differences. Therefore, in order to avoid this problem, it is required to adapt the detector trained with synthetic data to operate in the real-world scenario. In this paper, we propose a domain adaptation approach based on boosting LDA exemplar classifiers from both virtual and real worlds. We evaluate our proposal on multiple real-world pedestrian detection datasets. The results show that our method can efficiently adapt the exemplar classifiers from virtual to real world, avoiding drops in average precision over the 15%.