Abstract: Multi-domain recommender systems benefit from cross-domain representation learning and positive knowledge transfer. Both can be achieved by introducing a specific modeling of input data (i.e. disjoint history) or trying dedicated training regimes. At the same time, treating domains as separate input sources becomes a limitation as it does not capture the interplay that naturally exists between domains. In this work, we efficiently learn multi-domain representation of sequential users’ interactions using graph neural networks. We use temporal intra- and inter-domain interactions as contextual information for our method called MAGRec (short for Multi-dom Ain Graph-based Recommender). To better capture all relations in a multi-domain setting, we learn two graph-based sequential representations simultaneously: domain-guided for recent user interest, and general for long-term interest. This approach helps to mitigate the negative knowledge transfer problem from multiple domains and improve overall representation. We perform experiments on publicly available datasets in different scenarios where MAGRec consistently outperforms state-of-the-art methods. Furthermore, we provide an ablation study and discuss further extensions of our method.