Abstract: In this work we present a comprehensive computational framework to help in the clinical assessment of cancer response from a pair of time consecutive oncological PET-CT scans. In this scenario, the design and implementation of a supervised machine learning system to predict and quantify cancer progression or response conditions by introducing a novel feature set that models the underlying clinical context is described. Performance results in 100 clinical cases (corresponding to 200 whole body PET-CT scans) in comparing expert-based visual analysis and classifier decision making show up to 70% accuracy within a completely automatic pipeline and 90% accuracy when providing the system with expert-guided PET tumor segmentation masks.

Abstract: In this paper, we address two complex issues: 1) Text frame classification and 2) Multi-oriented text detection in video text frame. We first divide a video frame into 16 blocks and propose a combination of wavelet and median-moments with k-means clustering at the block level to identify probable text blocks. For each probable text block, the method applies the same combination of feature with k-means clustering over a sliding window running through the blocks to identify potential text candidates. We introduce a new idea of symmetry on text candidates in each block based on the observation that pixel distribution in text exhibits a symmetric pattern. The method integrates all blocks containing text candidates in the frame and then all text candidates are mapped on to a Sobel edge map of the original frame to obtain text representatives. To tackle the multi-orientation problem, we present a new method called Angle Projection Boundary Growing (APBG) which is an iterative algorithm and works based on a nearest neighbor concept. APBG is then applied on the text representatives to fix the bounding box for multi-oriented text lines in the video frame. Directional information is used to eliminate false positives. Experimental results on a variety of datasets such as non-horizontal, horizontal, publicly available data (Hua’s data) and ICDAR-03 competition data (camera images) show that the proposed method outperforms existing methods proposed for video and the state of the art methods for scene text as well.

Abstract: Intrinsic image decomposition is a challenging problem that consists in separating an image into its physical characteristics: reflectance and shading. This problem can be solved in different ways, but most methods have combined information from several visual cues. In this work we describe an extension of an existing method proposed by Serra et al. which considers two color descriptors and combines them by means of a Markov Random Field. We analyze in depth the weak points of the method and we explore more possibilities to use in both descriptors. The proposed extension depends on the combination of the cues considered to overcome some of the limitations of the original method. Our approach is tested on the MIT dataset and Beigpour et al. dataset, which contain images of real objects acquired under controlled conditions and synthetic images respectively, with their corresponding ground truth.

Abstract: By increasing popularity of wearable cameras, life-logging data analysis is becoming more and more important and useful to derive significant events out of this substantial collection of images. In this study, we introduce a new tracking method applied to visual life-logging, called bag-of-tracklets, which is based on detecting, localizing and tracking of people. Given the low spatial and temporal resolution of the image data, our model generates and groups tracklets in a unsupervised framework and extracts image sequences of person appearance according to a similarity score of the bag-of-tracklets. The model output is a meaningful sequence of events expressing human appearance and tracking them in life-logging data. The achieved results prove the robustness of our model in terms of efficiency and accuracy despite the low spatial and temporal resolution of the data.

Abstract: Empirical and mechanistic models differ in their approaches to the analysis of pharmacological effect. Whereas the parameters of the former are not physical constants those of the latter embody the nature, often complex, of biology. Empirical models are exclusively used for curve fitting, merely to characterize the shape of the E/[A] curves. Mechanistic models, on the contrary, enable the examination of mechanistic hypotheses by parameter simulation. Regretfully, the many parameters that mechanistic models may include can represent a great difficulty for curve fitting, representing, thus, a challenge for computational method development. In the present study some empirical and mechanistic models are shown and the connections, which may appear in a number of cases between them, are analyzed from the curves they yield. It may be concluded that systematic and careful curve shape analysis can be extremely useful for the understanding of receptor function, ligand classification and drug discovery, thus providing a common language for the communication between pharmacologists and medicinal chemists.

Abstract: The automatic segmentation of multiple subcortical structures in brain Magnetic Resonance Images (MRI) still remains a challenging task. In this paper, we address this problem using sparse representation and discriminative dictionary learning, which have shown promising results in compression, image denoising and recently in MRI segmentation. Particularly, we use multiclass dictionaries learned from a set of brain atlases to simultaneously segment multiple subcortical structures.
We also impose dictionary atoms to be specialized in one given class using label consistent K-SVD, which can alleviate the bias produced by unbalanced libraries, present when dealing with small structures. The proposed method is compared with other state of the art approaches for the segmentation of the Basal Ganglia of 35 subjects of a public dataset.
The promising results of the segmentation method show the eciency of the multiclass discriminative dictionary learning algorithms in MRI segmentation problems.

Abstract: In this paper we present a novel polyp region segmentation method for colonoscopy videos. Our method uses valley information associated to polyp boundaries in order to provide an initial segmentation. This first segmentation is refined to eliminate boundary discontinuities caused by image artifacts or other elements of the scene. Experimental results over a publicly annotated database show that our method outperforms both general and specific segmentation methods by providing more accurate regions rich in polyp content. We also prove how image preprocessing is needed to improve final polyp region segmentation.

Abstract: In this paper we present a wall segmentation approach in floor plans that is able to work independently to the graphical notation, does not need any pre-annotated data for learning, and is able to segment multiple-shaped walls such as beams and curved-walls. This method results from the combination of the wall segmentation approaches [3, 5] presented recently by the authors. Firstly, potential straight wall segments are extracted in an unsupervised way similar to [3], but restricting even more the wall candidates considered in the original approach. Then, based on [5], these segments are used to learn the texture pattern of walls and spot the lost instances. The presented combination of both methods has been tested on 4 available datasets with different notations and compared qualitatively and quantitatively to the state-of-the-art applied on these collections. Additionally, some qualitative results on floor plans directly downloaded from the Internet are reported in the paper. The overall performance of the method demonstrates either its adaptability to different wall notations and shapes, and to document qualities and resolutions.