Abstract: Recent advances in endoscopic technology have generated an increasing interest in strengthening the collaboration between clinicians and computers scientist to develop intelligent systems that can provide additional information to clinicians in the different stages of an intervention. The objective of this chapter is to identify clinical drawbacks of colonoscopy in order to define potential areas of collaboration. Once areas are defined, we present the challenges that colonoscopy images present in order computational methods to provide with meaningful output, including those related to image formation and acquisition, as they are proven to have an impact in the performance of an intelligent system. Finally, we also propose how to define validation frameworks in order to assess the performance of a given method, making an special emphasis on how databases should be created and annotated and which metrics should be used to evaluate systems correctly.

Abstract: Deformation of expressive textures is the gateway to realistic computer synthesis of expressions. By their good mathematical properties and flexible formulation on irregular meshes, most texture mappings rely on solutions to the Laplacian in the cartesian space. In the context of facial expression morphing, this approximation can be seen from the opposite point of view by neglecting the metric. In this paper, we use the properties of the Laplacian in manifolds to present a novel approach to warping expressive facial images in order to generate a morphing between them.

Abstract: In this paper we present a study on the use of Action Units as mid-level features for automatically recognizing basic and subtle emotions. We propose a representation model based on mid-level facial muscular movement features. We encode these movements dynamically using the Facial Action Coding System, and propose to use these intermediate features based on Action Units (AUs) to classify emotions. AUs activations are detected fusing a set of spatiotemporal geometric and appearance features. The algorithm is validated in two applications: (i) the recognition of 7 basic emotions using the publicly available Cohn-Kanade database, and (ii) the inference of subtle emotional cues in the Newscast database. In this second scenario, we consider emotions that are perceived cumulatively in longer periods of time. In particular, we Automatically classify whether video shoots from public News TV channels refer to Good or Bad news. To deal with the different video lengths we propose a Histogram of Action Units and compute it using a sliding window strategy on the frame sequences. Our approach achieves accuracies close to human perception.

Abstract: The oral communication competence is defined on the top of the most relevant skills for one's professional and personal life. Because of the importance of communication in our activities of daily living, it is crucial to study methods to evaluate and provide the necessary feedback that can be used in order to improve these communication capabilities and, therefore, learn how to express ourselves better. In this work, we propose a system capable of evaluating quantitatively the quality of oral presentations in an automatic fashion. The system is based on a multi-modal RGB, depth, and audio data description and a fusion approach in order to recognize behavioral cues and train classifiers able to eventually predict communication quality levels. The performance of the proposed system is tested on a novel dataset containing Bachelor thesis' real defenses, presentations from an 8th semester Bachelor courses, and Master courses' presentations at Universitat de Barcelona. Using as groundtruth the marks assigned by actual instructors, our system achieves high performance categorizing and ranking presentations by their quality, and also making real-valued mark predictions.

Abstract: Whole-body 3D PET/CT tumoral volume segmentation provides relevant diagnostic and prognostic information in clinical oncology and nuclear medicine. Carrying out this procedure manually by a medical expert is time consuming and suffers from inter- and intra-observer variabilities. In this paper, a completely automatic approach to this task is presented. First, the problem is stated and described both in clinical and technological terms. Then, a novel supervised learning segmentation framework is introduced. The segmentation by learning approach is defined within a Cascade of Adaboost classifiers and a 3D contextual proposal of Multiscale Stacked Sequential Learning. Segmentation accuracy results on 200 Breast Cancer whole body PET/CT volumes show mean 49% sensitivity, 99.993% specificity and 39% Jaccard overlap Index, which represent good performance results both at the clinical and technological level.

Abstract: We have previously developed an original method to evaluate small bowel motor function based on computer vision analysis of endoluminal images obtained by capsule endoscopy. Our aim was to demonstrate intestinal motor abnormalities in patients with functional bowel disorders by endoluminal vision analysis. Patients with functional bowel disorders (n = 205) and healthy subjects (n = 136) ingested the endoscopic capsule (Pillcam-SB2, Given-Imaging) after overnight fast and 45 min after gastric exit of the capsule a liquid meal (300 ml, 1 kcal/ml) was administered. Endoluminal image analysis was performed by computer vision and machine learning techniques to define the normal range and to identify clusters of abnormal function. After training the algorithm, we used 196 patients and 48 healthy subjects, completely naive, as test set. In the test set, 51 patients (26%) were detected outside the normal range (P < 0.001 vs. 3 healthy subjects) and clustered into hypo- and hyperdynamic subgroups compared with healthy subjects. Patients with hypodynamic behavior (n = 38) exhibited less luminal closure sequences (41 ± 2% of the recording time vs. 61 ± 2%; P < 0.001) and more static sequences (38 ± 3 vs. 20 ± 2%; P < 0.001); in contrast, patients with hyperdynamic behavior (n = 13) had an increased proportion of luminal closure sequences (73 ± 4 vs. 61 ± 2%; P = 0.029) and more high-motion sequences (3 ± 1 vs. 0.5 ± 0.1%; P < 0.001). Applying an original methodology, we have developed a novel classification of functional gut disorders based on objective, physiological criteria of small bowel function.