Frederic Sampedro, Anna Domenech, Sergio Escalera, & Ignasi Carrio. (2015). Deriving global quantitative tumor response parameters from 18F-FDG PET-CT scans in patients with non-Hodgkins lymphoma. NMC - Nuclear Medicine Communications, 36(4), 328–333.
Abstract: OBJECTIVES:
The aim of the study was to address the need for quantifying the global cancer time evolution magnitude from a pair of time-consecutive positron emission tomography-computed tomography (PET-CT) scans. In particular, we focus on the computation of indicators using image-processing techniques that seek to model non-Hodgkin's lymphoma (NHL) progression or response severity.
MATERIALS AND METHODS:
A total of 89 pairs of time-consecutive PET-CT scans from NHL patients were stored in a nuclear medicine station for subsequent analysis. These were classified by a consensus of nuclear medicine physicians into progressions, partial responses, mixed responses, complete responses, and relapses. The cases of each group were ordered by magnitude following visual analysis. Thereafter, a set of quantitative indicators designed to model the cancer evolution magnitude within each group were computed using semiautomatic and automatic image-processing techniques. Performance evaluation of the proposed indicators was measured by a correlation analysis with the expert-based visual analysis.
RESULTS:
The set of proposed indicators achieved Pearson's correlation results in each group with respect to the expert-based visual analysis: 80.2% in progressions, 77.1% in partial response, 68.3% in mixed response, 88.5% in complete response, and 100% in relapse. In the progression and mixed response groups, the proposed indicators outperformed the common indicators used in clinical practice [changes in metabolic tumor volume, mean, maximum, peak standardized uptake value (SUV mean, SUV max, SUV peak), and total lesion glycolysis] by more than 40%.
CONCLUSION:
Computing global indicators of NHL response using PET-CT imaging techniques offers a strong correlation with the associated expert-based visual analysis, motivating the future incorporation of such quantitative and highly observer-independent indicators in oncological decision making or treatment response evaluation scenarios.
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Frederic Sampedro, Sergio Escalera, Anna Domenech, & Ignasi Carrio. (2014). A computational framework for cancer response assessment based on oncological PET-CT scans. CBM - Computers in Biology and Medicine, 55, 92–99.
Abstract: In this work we present a comprehensive computational framework to help in the clinical assessment of cancer response from a pair of time consecutive oncological PET-CT scans. In this scenario, the design and implementation of a supervised machine learning system to predict and quantify cancer progression or response conditions by introducing a novel feature set that models the underlying clinical context is described. Performance results in 100 clinical cases (corresponding to 200 whole body PET-CT scans) in comparing expert-based visual analysis and classifier decision making show up to 70% accuracy within a completely automatic pipeline and 90% accuracy when providing the system with expert-guided PET tumor segmentation masks.
Keywords: Computer aided diagnosis; Nuclear medicine; Machine learning; Image processing; Quantitative analysis
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Maedeh Aghaei, & Petia Radeva. (2014). Bag-of-Tracklets for Person Tracking in Life-Logging Data. In 17th International Conference of the Catalan Association for Artificial Intelligence (Vol. 269, pp. 35–44).
Abstract: By increasing popularity of wearable cameras, life-logging data analysis is becoming more and more important and useful to derive significant events out of this substantial collection of images. In this study, we introduce a new tracking method applied to visual life-logging, called bag-of-tracklets, which is based on detecting, localizing and tracking of people. Given the low spatial and temporal resolution of the image data, our model generates and groups tracklets in a unsupervised framework and extracts image sequences of person appearance according to a similarity score of the bag-of-tracklets. The model output is a meaningful sequence of events expressing human appearance and tracking them in life-logging data. The achieved results prove the robustness of our model in terms of efficiency and accuracy despite the low spatial and temporal resolution of the data.
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Enric Marti, J.Roncaries, Debora Gil, Aura Hernandez-Sabate, Antoni Gurgui, & Ferran Poveda. (2015). PBL On Line: A proposal for the organization, part-time monitoring and assessment of PBL group activities. JOTSE - Journal of Technology and Science Education, 87–96.
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Jorge Bernal, F. Javier Sanchez, Gloria Fernandez Esparrach, Debora Gil, Cristina Rodriguez de Miguel, & Fernando Vilariño. (2015). WM-DOVA Maps for Accurate Polyp Highlighting in Colonoscopy: Validation vs. Saliency Maps from Physicians. CMIG - Computerized Medical Imaging and Graphics, 43, 99–111.
Abstract: We introduce in this paper a novel polyp localization method for colonoscopy videos. Our method is based on a model of appearance for polyps which defines polyp boundaries in terms of valley information. We propose the integration of valley information in a robust way fostering complete, concave and continuous boundaries typically associated to polyps. This integration is done by using a window of radial sectors which accumulate valley information to create WMDOVA1 energy maps related with the likelihood of polyp presence. We perform a double validation of our maps, which include the introduction of two new databases, including the first, up to our knowledge, fully annotated database with clinical metadata associated. First we assess that the highest value corresponds with the location of the polyp in the image. Second, we show that WM-DOVA energy maps can be comparable with saliency maps obtained from physicians' fixations obtained via an eye-tracker. Finally, we prove that our method outperforms state-of-the-art computational saliency results. Our method shows good performance, particularly for small polyps which are reported to be the main sources of polyp miss-rate, which indicates the potential applicability of our method in clinical practice.
Keywords: Polyp localization; Energy Maps; Colonoscopy; Saliency; Valley detection
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Carles Sanchez, Oriol Ramos Terrades, Patricia Marquez, Enric Marti, J.Roncaries, & Debora Gil. (2015). Automatic evaluation of practices in Moodle for Self Learning in Engineering. JOTSE - Journal of Technology and Science Education, 97–106.
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Carles Sanchez, Jorge Bernal, F. Javier Sanchez, Antoni Rosell, Marta Diez-Ferrer, & Debora Gil. (2015). Towards On-line Quantification of Tracheal Stenosis from Videobronchoscopy. IJCAR - International Journal of Computer Assisted Radiology and Surgery, 10(6), 935–945.
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Carles Sanchez, Debora Gil, R. Tazi, Jorge Bernal, Y. Ruiz, L. Planas, et al. (2015). Quasi-real time digital assessment of Central Airway Obstruction. In 3rd European congress for bronchology and interventional pulmonology ECBIP2015.
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Carles Sanchez, Jorge Bernal, F. Javier Sanchez, Marta Diez-Ferrer, Antoni Rosell, & Debora Gil. (2015). Towards On-line Quantification of Tracheal Stenosis from Videobronchoscopy. In 6th International Conference on Information Processing in Computer-Assisted Interventions IPCAI2015 (Vol. 10, pp. 935–945).
Abstract: PURPOSE:
Lack of objective measurement of tracheal obstruction degree has a negative impact on the chosen treatment prone to lead to unnecessary repeated explorations and other scanners. Accurate computation of tracheal stenosis in videobronchoscopy would constitute a breakthrough for this noninvasive technique and a reduction in operation cost for the public health service.
METHODS:
Stenosis calculation is based on the comparison of the region delimited by the lumen in an obstructed frame and the region delimited by the first visible ring in a healthy frame. We propose a parametric strategy for the extraction of lumen and tracheal ring regions based on models of their geometry and appearance that guide a deformable model. To ensure a systematic applicability, we present a statistical framework to choose optimal parametric values and a strategy to choose the frames that minimize the impact of scope optical distortion.
RESULTS:
Our method has been tested in 40 cases covering different stenosed tracheas. Experiments report a non- clinically relevant [Formula: see text] of discrepancy in the calculated stenotic area and a computational time allowing online implementation in the operating room.
CONCLUSIONS:
Our methodology allows reliable measurements of airway narrowing in the operating room. To fully assess its clinical impact, a prospective clinical trial should be done.
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Antoni Gurgui, Debora Gil, & Enric Marti. (2015). Laplacian Unitary Domain for Texture Morphing. In Proceedings of the 10th International Conference on Computer Vision Theory and Applications VISIGRAPP2015 (Vol. 1, pp. 693–699). SciTePress.
Abstract: Deformation of expressive textures is the gateway to realistic computer synthesis of expressions. By their good mathematical properties and flexible formulation on irregular meshes, most texture mappings rely on solutions to the Laplacian in the cartesian space. In the context of facial expression morphing, this approximation can be seen from the opposite point of view by neglecting the metric. In this paper, we use the properties of the Laplacian in manifolds to present a novel approach to warping expressive facial images in order to generate a morphing between them.
Keywords: Facial; metamorphosis;LaplacianMorphing
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Sergio Vera, Miguel Angel Gonzalez Ballester, & Debora Gil. (2015). A Novel Cochlear Reference Frame Based On The Laplace Equation. In 29th international Congress and Exhibition on Computer Assisted Radiology and Surgery (Vol. 10, pp. 1–312).
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Hanne Kause, Patricia Marquez, Andrea Fuster, Aura Hernandez-Sabate, Luc Florack, Debora Gil, et al. (2015). Quality Assessment of Optical Flow in Tagging MRI. In 5th Dutch Bio-Medical Engineering Conference BME2015.
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Olivier Lefebvre, Pau Riba, Charles Fournier, Alicia Fornes, Josep Llados, Rejean Plamondon, et al. (2015). Monitoring neuromotricity on-line: a cloud computing approach. In 17th Conference of the International Graphonomics Society IGS2015.
Abstract: The goal of our experiment is to develop a useful and accessible tool that can be used to evaluate a patient's health by analyzing handwritten strokes. We use a cloud computing approach to analyze stroke data sampled on a commercial tablet working on the Android platform and a distant server to perform complex calculations using the Delta and Sigma lognormal algorithms. A Google Drive account is used to store the data and to ease the development of the project. The communication between the tablet, the cloud and the server is encrypted to ensure biomedical information confidentiality. Highly parameterized biomedical tests are implemented on the tablet as well as a free drawing test to evaluate the validity of the data acquired by the first test compared to the second one. A blurred shape model descriptor pattern recognition algorithm is used to classify the data obtained by the free drawing test. The functions presented in this paper are still currently under development and other improvements are needed before launching the application in the public domain.
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Pau Riba, Josep Llados, Alicia Fornes, & Anjan Dutta. (2015). Large-scale Graph Indexing using Binary Embeddings of Node Contexts. In C.-L.Liu, B.Luo, W.G.Kropatsch, & J.Cheng (Eds.), 10th IAPR-TC15 Workshop on Graph-based Representations in Pattern Recognition (Vol. 9069, pp. 208–217). LNCS. Springer International Publishing.
Abstract: Graph-based representations are experiencing a growing usage in visual recognition and retrieval due to their representational power in front of classical appearance-based representations in terms of feature vectors. Retrieving a query graph from a large dataset of graphs has the drawback of the high computational complexity required to compare the query and the target graphs. The most important property for a large-scale retrieval is the search time complexity to be sub-linear in the number of database examples. In this paper we propose a fast indexation formalism for graph retrieval. A binary embedding is defined as hashing keys for graph nodes. Given a database of labeled graphs, graph nodes are complemented with vectors of attributes representing their local context. Hence, each attribute counts the length of a walk of order k originated in a vertex with label l. Each attribute vector is converted to a binary code applying a binary-valued hash function. Therefore, graph retrieval is formulated in terms of finding target graphs in the database whose nodes have a small Hamming distance from the query nodes, easily computed with bitwise logical operators. As an application example, we validate the performance of the proposed methods in a handwritten word spotting scenario in images of historical documents.
Keywords: Graph matching; Graph indexing; Application in document analysis; Word spotting; Binary embedding
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R. Clariso, David Masip, & A. Rius. (2014). Student projects empowering mobile learning in higher education. RUSC - Revista de Universidad y Sociedad del Conocimiento, 192–207.
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