Abstract: We have previously developed an original method to evaluate small bowel motor function based on computer vision analysis of endoluminal images obtained by capsule endoscopy. Our aim was to demonstrate intestinal motor abnormalities in patients with functional bowel disorders by endoluminal vision analysis. Patients with functional bowel disorders (n = 205) and healthy subjects (n = 136) ingested the endoscopic capsule (Pillcam-SB2, Given-Imaging) after overnight fast and 45 min after gastric exit of the capsule a liquid meal (300 ml, 1 kcal/ml) was administered. Endoluminal image analysis was performed by computer vision and machine learning techniques to define the normal range and to identify clusters of abnormal function. After training the algorithm, we used 196 patients and 48 healthy subjects, completely naive, as test set. In the test set, 51 patients (26%) were detected outside the normal range (P < 0.001 vs. 3 healthy subjects) and clustered into hypo- and hyperdynamic subgroups compared with healthy subjects. Patients with hypodynamic behavior (n = 38) exhibited less luminal closure sequences (41 ± 2% of the recording time vs. 61 ± 2%; P < 0.001) and more static sequences (38 ± 3 vs. 20 ± 2%; P < 0.001); in contrast, patients with hyperdynamic behavior (n = 13) had an increased proportion of luminal closure sequences (73 ± 4 vs. 61 ± 2%; P = 0.029) and more high-motion sequences (3 ± 1 vs. 0.5 ± 0.1%; P < 0.001). Applying an original methodology, we have developed a novel classification of functional gut disorders based on objective, physiological criteria of small bowel function.

Abstract: In this work, we develop a generic framework that is able to handle the document retrieval problem in various scenarios such as searching for full page matches or retrieving the counterparts for specific document areas, focusing on their structural similarity or letting their visual resemblance to play a dominant role. Based on the spatial indexing technique, we propose to search for matches of local key-region pairs carrying both structural and visual information from the collection while a scheme allowing to adjust the relative contribution of structural and visual similarity is presented.
Based on the fact that the structure of documents is tightly linked with the distance among their elements, we firstly introduce an efficient detector named Distance Transform based Maximally Stable Extremal Regions (DTMSER). We illustrate that this detector is able to efficiently extract the structure of a document image as a dendrogram (hierarchical tree) of multi-scale key-regions that roughly correspond to letters, words and paragraphs. We demonstrate that, without benefiting from the structure information, the key-regions extracted by the DTMSER algorithm achieve better results comparing with state-of-the-art methods while much less amount of key-regions are employed.
We subsequently propose a pair-wise Bag of Words (BoW) framework to efficiently embed the explicit structure extracted by the DTMSER algorithm. We represent each document as a list of key-region pairs that correspond to the edges in the dendrogram where inclusion relationship is encoded. By employing those structural key-region pairs as the pooling elements for generating the histogram of features, the proposed method is able to encode the explicit inclusion relations into a BoW representation. The experimental results illustrate that the pair-wise BoW, powered by the embedded structural information, achieves remarkable improvement over the conventional BoW and spatial pyramidal BoW methods.
To handle various retrieval scenarios in one framework, we propose to directly query a series of key-region pairs, carrying both structure and visual information, from the collection. We introduce the spatial indexing techniques to the document retrieval community to speed up the structural relationship computation for key-region pairs. We firstly test the proposed framework in a full page retrieval scenario where structurally similar matches are expected. In this case, the pair-wise querying method achieves notable improvement over the BoW and spatial pyramidal BoW frameworks. Furthermore, we illustrate that the proposed method is also able to handle focused retrieval situations where the queries are defined as a specific interesting partial areas of the images. We examine our method on two types of focused queries: structure-focused and exact queries. The experimental results show that, the proposed generic framework obtains nearly perfect precision on both types of focused queries while it is the first framework able to tackle structure-focused queries, setting a new state of the art in the field.
Besides, we introduce a line verification method to check the spatial consistency among the matched key-region pairs. We propose a computationally efficient version of line verification through a two step implementation. We first compute tentative localizations of the query and subsequently employ them to divide the matched key-region pairs into several groups, then line verification is performed within each group while more precise bounding boxes are computed. We demonstrate that, comparing with the standard approach (based on RANSAC), the line verification proposed generally achieves much higher recall with slight loss on precision on specific queries.

Abstract: Optical Flow (OF) is the input of a wide range of decision support systems such as car driver assistance, UAV guiding or medical diagnose. In these real situations, the absence of ground truth forces to assess OF quality using quantities computed from either sequences or the computed optical flow itself. These quantities are generally known as Confidence Measures, CM. Even if we have a proper confidence measure we still need a way to evaluate its ability to discard pixels with an OF prone to have a large error. Current approaches only provide a descriptive evaluation of the CM performance but such approaches are not capable to fairly compare different confidence measures and optical flow algorithms. Thus, it is of prime importance to define a framework and a general road map for the evaluation of optical flow performance.
This thesis provides a framework able to decide which pairs “ optical flow – confidence measure” (OF-CM) are best suited for optical flow error bounding given a confidence level determined by a decision support system. To design this framework we cover the following points:
Descriptive scores. As a first step, we summarize and analyze the sources of inaccuracies in the output of optical flow algorithms. Second, we present several descriptive plots that visually assess CM capabilities for OF error bounding. In addition to the descriptive plots, given a plot representing OF-CM capabilities to bound the error, we provide a numeric score that categorizes the plot according to its decreasing profile, that is, a score assessing CM performance.
Statistical framework. We provide a comparison framework that assesses the best suited OF-CM pair for error bounding that uses a two stage cascade process. First of all we assess the predictive value of the confidence measures by means of a descriptive plot. Then, for a sample of descriptive plots computed over training frames, we obtain a generic curve that will be used for sequences with no ground truth. As a second step, we evaluate the obtained general curve and its capabilities to really reflect the predictive value of a confidence measure using the variability across train frames by means of ANOVA.
The presented framework has shown its potential in the application on clinical decision support systems. In particular, we have analyzed the impact of the different image artifacts such as noise and decay to the output of optical flow in a cardiac diagnose system and we have improved the navigation inside the bronchial tree on bronchoscopy.

Abstract: Pedestrian detection continues to be an extremely challenging problem in real scenarios, in which situations like illumination changes, noisy images, unexpected objects, uncontrolled scenarios and variant appearance of objects occur constantly. All these problems force the development of more robust detectors for relevant applications like vision-based autonomous vehicles, intelligent surveillance, and pedestrian tracking for behavior analysis. Most reliable vision-based pedestrian detectors base their decision on features extracted using a single sensor capturing complementary features, e.g., appearance, and texture. These features usually are extracted from the current frame, ignoring temporal information, or including it in a post process step e.g., tracking or temporal coherence. Taking into account these issues we formulate the following question: can we generate more robust pedestrian detectors by introducing new information sources in the feature extraction step?
In order to answer this question we develop different approaches for introducing new information sources to well-known pedestrian detectors. We start by the inclusion of temporal information following the Stacked Sequential Learning (SSL) paradigm which suggests that information extracted from the neighboring samples in a sequence can improve the accuracy of a base classifier.
We then focus on the inclusion of complementary information from different sensors like 3D point clouds (LIDAR – depth), far infrared images (FIR), or disparity maps (stereo pair cameras). For this end we develop a multi-modal framework in which information from different sensors is used for increasing detection accuracy (by increasing information redundancy). Finally we propose a multi-view pedestrian detector, this multi-view approach splits the detection problem in n sub-problems.
Each sub-problem will detect objects in a given specific view reducing in that way the variability problem faced when a single detectors is used for the whole problem. We show that these approaches obtain competitive results with other state-of-the-art methods but instead of design new features, we reuse existing ones boosting their performance.

Abstract: Image registration has been for many years the gold standard method to bring two images into correspondence. It has been used extensively in the eld of medical imaging in order to put images of dierent patients into a common overlapping spatial position. However, medical image registration is a slow, iterative optimization process, where many variables and prone to fall into the pit traps local minima.
A coordinate system parameterizing the interior of organs is a powerful tool for a systematic localization of injured tissue. If the same coordinate values are assigned to specic anatomical sites, parameterizations ensure integration of data across different medical image modalities. Harmonic mappings have been used to produce parametric meshes over the surface of anatomical shapes, given their ability to set values at specic locations through boundary conditions. However, most of the existing implementations in medical imaging restrict to either anatomical surfaces, or the depth coordinate with boundary conditions is given at discrete sites of limited geometric diversity.
The medial surface of the shape can be used to provide a continuous basis for the denition of a depth coordinate. However, given that dierent methods for generation of medial surfaces generate dierent manifolds, not all of them are equally suited to be the basis of radial coordinate for a parameterization. It would be desirable that the medial surface will be smooth, and robust to surface shape noise, with low number of spurious branches or surfaces.
In this thesis we present methods for computation of smooth medial manifolds and apply them to the generation of for anatomical volumetric parameterization that extends current harmonic parameterizations to the interior anatomy using information provided by the volume medial surface. This reference system sets a solid base for creating anatomical models of the anatomical shapes, and allows comparing several patients in a common framework of reference.

Abstract: In this paper we present a study on the use of Action Units as mid-level features for automatically recognizing basic and subtle emotions. We propose a representation model based on mid-level facial muscular movement features. We encode these movements dynamically using the Facial Action Coding System, and propose to use these intermediate features based on Action Units (AUs) to classify emotions. AUs activations are detected fusing a set of spatiotemporal geometric and appearance features. The algorithm is validated in two applications: (i) the recognition of 7 basic emotions using the publicly available Cohn-Kanade database, and (ii) the inference of subtle emotional cues in the Newscast database. In this second scenario, we consider emotions that are perceived cumulatively in longer periods of time. In particular, we Automatically classify whether video shoots from public News TV channels refer to Good or Bad news. To deal with the different video lengths we propose a Histogram of Action Units and compute it using a sliding window strategy on the frame sequences. Our approach achieves accuracies close to human perception.

Abstract: Human-robot interaction is a hot topic nowadays in the social robotics
community. One crucial aspect is represented by the affective communication
which comes encoded through the facial expressions. In this chapter, we propose a novel approach for facial expression recognition, which exploits an efficient and adaptive graph-based label propagation (semi-supervised mode) in a multi-observation framework. The facial features are extracted using an appearance-based 3D face tracker, viewand texture independent. Our method has been extensively tested on the CMU dataset, and has been conveniently compared with other methods for graph construction. With the proposed approach, we developed an application for an AIBO robot, in which it mirrors the recognized facial
expression.