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Marta Ligero, Alonso Garcia Ruiz, Cristina Viaplana, Guillermo Villacampa, Maria V Raciti, Jaid Landa, et al. (2021). A CT-based radiomics signature is associated with response to immune checkpoint inhibitors in advanced solid tumors. Radiology, 299(1), 109–119.
Abstract: Background Reliable predictive imaging markers of response to immune checkpoint inhibitors are needed. Purpose To develop and validate a pretreatment CT-based radiomics signature to predict response to immune checkpoint inhibitors in advanced solid tumors. Materials and Methods In this retrospective study, a radiomics signature was developed in patients with advanced solid tumors (including breast, cervix, gastrointestinal) treated with anti-programmed cell death-1 or programmed cell death ligand-1 monotherapy from August 2012 to May 2018 (cohort 1). This was tested in patients with bladder and lung cancer (cohorts 2 and 3). Radiomics variables were extracted from all metastases delineated at pretreatment CT and selected by using an elastic-net model. A regression model combined radiomics and clinical variables with response as the end point. Biologic validation of the radiomics score with RNA profiling of cytotoxic cells (cohort 4) was assessed with Mann-Whitney analysis. Results The radiomics signature was developed in 85 patients (cohort 1: mean age, 58 years ± 13 [standard deviation]; 43 men) and tested on 46 patients (cohort 2: mean age, 70 years ± 12; 37 men) and 47 patients (cohort 3: mean age, 64 years ± 11; 40 men). Biologic validation was performed in a further cohort of 20 patients (cohort 4: mean age, 60 years ± 13; 14 men). The radiomics signature was associated with clinical response to immune checkpoint inhibitors (area under the curve [AUC], 0.70; 95% CI: 0.64, 0.77; P < .001). In cohorts 2 and 3, the AUC was 0.67 (95% CI: 0.58, 0.76) and 0.67 (95% CI: 0.56, 0.77; P < .001), respectively. A radiomics-clinical signature (including baseline albumin level and lymphocyte count) improved on radiomics-only performance (AUC, 0.74 [95% CI: 0.63, 0.84; P < .001]; Akaike information criterion, 107.00 and 109.90, respectively). Conclusion A pretreatment CT-based radiomics signature is associated with response to immune checkpoint inhibitors, likely reflecting the tumor immunophenotype. © RSNA, 2021 Online supplemental material is available for this article. See also the editorial by Summers in this issue.
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Javier Marin, & Sergio Escalera. (2021). SSSGAN: Satellite Style and Structure Generative Adversarial Networks. Remote Sensing, 13(19), 3984.
Abstract: This work presents Satellite Style and Structure Generative Adversarial Network (SSGAN), a generative model of high resolution satellite imagery to support image segmentation. Based on spatially adaptive denormalization modules (SPADE) that modulate the activations with respect to segmentation map structure, in addition to global descriptor vectors that capture the semantic information in a vector with respect to Open Street Maps (OSM) classes, this model is able to produce
consistent aerial imagery. By decoupling the generation of aerial images into a structure map and a carefully defined style vector, we were able to improve the realism and geodiversity of the synthesis with respect to the state-of-the-art baseline. Therefore, the proposed model allows us to control the generation not only with respect to the desired structure, but also with respect to a geographic area. |
Jose Luis Gomez, Gabriel Villalonga, & Antonio Lopez. (2021). Co-Training for Deep Object Detection: Comparing Single-Modal and Multi-Modal Approaches. SENS - Sensors, 21(9), 3185.
Abstract: Top-performing computer vision models are powered by convolutional neural networks (CNNs). Training an accurate CNN highly depends on both the raw sensor data and their associated ground truth (GT). Collecting such GT is usually done through human labeling, which is time-consuming and does not scale as we wish. This data-labeling bottleneck may be intensified due to domain shifts among image sensors, which could force per-sensor data labeling. In this paper, we focus on the use of co-training, a semi-supervised learning (SSL) method, for obtaining self-labeled object bounding boxes (BBs), i.e., the GT to train deep object detectors. In particular, we assess the goodness of multi-modal co-training by relying on two different views of an image, namely, appearance (RGB) and estimated depth (D). Moreover, we compare appearance-based single-modal co-training with multi-modal. Our results suggest that in a standard SSL setting (no domain shift, a few human-labeled data) and under virtual-to-real domain shift (many virtual-world labeled data, no human-labeled data) multi-modal co-training outperforms single-modal. In the latter case, by performing GAN-based domain translation both co-training modalities are on par, at least when using an off-the-shelf depth estimation model not specifically trained on the translated images.
Keywords: co-training; multi-modality; vision-based object detection; ADAS; self-driving
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Yasuko Sugito, Trevor Canham, Javier Vazquez, & Marcelo Bertalmio. (2021). A Study of Objective Quality Metrics for HLG-Based HDR/WCG Image Coding. SMPTE - SMPTE Motion Imaging Journal, 53–65.
Abstract: In this work, we study the suitability of high dynamic range, wide color gamut (HDR/WCG) objective quality metrics to assess the perceived deterioration of compressed images encoded using the hybrid log-gamma (HLG) method, which is the standard for HDR television. Several image quality metrics have been developed to deal specifically with HDR content, although in previous work we showed that the best results (i.e., better matches to the opinion of human expert observers) are obtained by an HDR metric that consists simply in applying a given standard dynamic range metric, called visual information fidelity (VIF), directly to HLG-encoded images. However, all these HDR metrics ignore the chroma components for their calculations, that is, they consider only the luminance channel. For this reason, in the current work, we conduct subjective evaluation experiments in a professional setting using compressed HDR/WCG images encoded with HLG and analyze the ability of the best HDR metric to detect perceivable distortions in the chroma components, as well as the suitability of popular color metrics (including ΔITPR , which supports parameters for HLG) to correlate with the opinion scores. Our first contribution is to show that there is a need to consider the chroma components in HDR metrics, as there are color distortions that subjects perceive but that the best HDR metric fails to detect. Our second contribution is the surprising result that VIF, which utilizes only the luminance channel, correlates much better with the subjective evaluation scores than the metrics investigated that do consider the color components.
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Michael Teutsch, Angel Sappa, & Riad I. Hammoud. (2021). Computer Vision in the Infrared Spectrum: Challenges and Approaches (Vol. 10).
Abstract: Human visual perception is limited to the visual-optical spectrum. Machine vision is not. Cameras sensitive to the different infrared spectra can enhance the abilities of autonomous systems and visually perceive the environment in a holistic way. Relevant scene content can be made visible especially in situations, where sensors of other modalities face issues like a visual-optical camera that needs a source of illumination. As a consequence, not only human mistakes can be avoided by increasing the level of automation, but also machine-induced errors can be reduced that, for example, could make a self-driving car crash into a pedestrian under difficult illumination conditions. Furthermore, multi-spectral sensor systems with infrared imagery as one modality are a rich source of information and can provably increase the robustness of many autonomous systems. Applications that can benefit from utilizing infrared imagery range from robotics to automotive and from biometrics to surveillance. In this book, we provide a brief yet concise introduction to the current state-of-the-art of computer vision and machine learning in the infrared spectrum. Based on various popular computer vision tasks such as image enhancement, object detection, or object tracking, we first motivate each task starting from established literature in the visual-optical spectrum. Then, we discuss the differences between processing images and videos in the visual-optical spectrum and the various infrared spectra. An overview of the current literature is provided together with an outlook for each task. Furthermore, available and annotated public datasets and common evaluation methods and metrics are presented. In a separate chapter, popular applications that can greatly benefit from the use of infrared imagery as a data source are presented and discussed. Among them are automatic target recognition, video surveillance, or biometrics including face recognition. Finally, we conclude with recommendations for well-fitting sensor setups and data processing algorithms for certain computer vision tasks. We address this book to prospective researchers and engineers new to the field but also to anyone who wants to get introduced to the challenges and the approaches of computer vision using infrared images or videos. Readers will be able to start their work directly after reading the book supported by a highly comprehensive backlog of recent and relevant literature as well as related infrared datasets including existing evaluation frameworks. Together with consistently decreasing costs for infrared cameras, new fields of application appear and make computer vision in the infrared spectrum a great opportunity to face nowadays scientific and engineering challenges.
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Albin Soutif, Marc Masana, Joost Van de Weijer, & Bartlomiej Twardowski. (2021). On the importance of cross-task features for class-incremental learning. In Theory and Foundation of continual learning workshop of ICML.
Abstract: In class-incremental learning, an agent with limited resources needs to learn a sequence of classification tasks, forming an ever growing classification problem, with the constraint of not being able to access data from previous tasks. The main difference with task-incremental learning, where a task-ID is available at inference time, is that the learner also needs to perform crosstask discrimination, i.e. distinguish between classes that have not been seen together. Approaches to tackle this problem are numerous and mostly make use of an external memory (buffer) of non-negligible size. In this paper, we ablate the learning of crosstask features and study its influence on the performance of basic replay strategies used for class-IL. We also define a new forgetting measure for class-incremental learning, and see that forgetting is not the principal cause of low performance. Our experimental results show that future algorithms for class-incremental learning should not only prevent forgetting, but also aim to improve the quality of the cross-task features. This is especially important when the number of classes per task is small.
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Shiqi Yang, Yaxing Wang, Joost Van de Weijer, Luis Herranz, & Shangling Jui. (2021). Exploiting the Intrinsic Neighborhood Structure for Source-free Domain Adaptation. In Thirty-fifth Conference on Neural Information Processing Systems (NeurIPS 2021).
Abstract: Domain adaptation (DA) aims to alleviate the domain shift between source domain and target domain. Most DA methods require access to the source data, but often that is not possible (e.g. due to data privacy or intellectual property). In this paper, we address the challenging source-free domain adaptation (SFDA) problem, where the source pretrained model is adapted to the target domain in the absence of source data. Our method is based on the observation that target data, which might no longer align with the source domain classifier, still forms clear clusters. We capture this intrinsic structure by defining local affinity of the target data, and encourage label consistency among data with high local affinity. We observe that higher affinity should be assigned to reciprocal neighbors, and propose a self regularization loss to decrease the negative impact of noisy neighbors. Furthermore, to aggregate information with more context, we consider expanded neighborhoods with small affinity values. In the experimental results we verify that the inherent structure of the target features is an important source of information for domain adaptation. We demonstrate that this local structure can be efficiently captured by considering the local neighbors, the reciprocal neighbors, and the expanded neighborhood. Finally, we achieve state-of-the-art performance on several 2D image and 3D point cloud recognition datasets. Code is available in https://github.com/Albert0147/SFDA_neighbors.
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Xim Cerda-Company, Olivier Penacchio, & Xavier Otazu. (2021). Chromatic Induction in Migraine. VISION, 37.
Abstract: The human visual system is not a colorimeter. The perceived colour of a region does not only depend on its colour spectrum, but also on the colour spectra and geometric arrangement of neighbouring regions, a phenomenon called chromatic induction. Chromatic induction is thought to be driven by lateral interactions: the activity of a central neuron is modified by stimuli outside its classical receptive field through excitatory–inhibitory mechanisms. As there is growing evidence of an excitation/inhibition imbalance in migraine, we compared chromatic induction in migraine and control groups. As hypothesised, we found a difference in the strength of induction between the two groups, with stronger induction effects in migraine. On the other hand, given the increased prevalence of visual phenomena in migraine with aura, we also hypothesised that the difference between migraine and control would be more important in migraine with aura than in migraine without aura. Our experiments did not support this hypothesis. Taken together, our results suggest a link between excitation/inhibition imbalance and increased induction effects.
Keywords: migraine; vision; colour; colour perception; chromatic induction; psychophysics
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