Abstract: Pairwise classification is a well-known class binarization technique that converts a multiclass problem into a number of two-class problems, one problem for each pair of classes. However, in the pairwise technique, nuisance votes of many irrelevant classifiers may result in a wrong class prediction. To overcome this problem, a simple, but efficient method is proposed and evaluated in this paper. The proposed method is based on excluding some classes and focusing on the most probable classes in the neighborhood space, named Local Crossing Off (LCO). This procedure is performed by employing a modified version of standard K-nearest neighbor and large margin nearest neighbor algorithms. The LCO method takes advantage of nearest neighbor classification algorithm because of its local learning behavior as well as the global behavior of powerful binary classifiers to discriminate between two classes. Combining these two properties in the proposed LCO technique will avoid the weaknesses of each method and will increase the efficiency of the whole classification system. On several benchmark datasets of varying size and difficulty, we found that the LCO approach leads to significant improvements using different base learners. The experimental results show that the proposed technique not only achieves better classification accuracy in comparison to other standard approaches, but also is computationally more efficient for tackling classification problems which have a relatively large number of target classes.

Abstract: Multiple classifier systems, also known as classifier ensembles, have received great attention in recent years because of their improved classification accuracy in different applications. In this paper, we propose a new general approach to ensemble classification, named generic subclass ensemble, in which each base classifier is trained with data belonging to a subset of classes, and thus discriminates among a subset of target categories. The ensemble classifiers are then fused using a combination rule. The proposed approach differs from existing methods that manipulate the target attribute, since in our approach individual classification problems are not restricted to two-class problems. We perform a series of experiments to evaluate the efficiency of the generic subclass approach on a set of benchmark datasets. Experimental results with multilayer perceptrons show that the proposed approach presents a viable alternative to the most commonly used ensemble classification approaches.

Abstract: Whole-body 3D PET/CT tumoral volume segmentation provides relevant diagnostic and prognostic information in clinical oncology and nuclear medicine. Carrying out this procedure manually by a medical expert is time consuming and suffers from inter- and intra-observer variabilities. In this paper, a completely automatic approach to this task is presented. First, the problem is stated and described both in clinical and technological terms. Then, a novel supervised learning segmentation framework is introduced. The segmentation by learning approach is defined within a Cascade of Adaboost classifiers and a 3D contextual proposal of Multiscale Stacked Sequential Learning. Segmentation accuracy results on 200 Breast Cancer whole body PET/CT volumes show mean 49% sensitivity, 99.993% specificity and 39% Jaccard overlap Index, which represent good performance results both at the clinical and technological level.

Abstract: In this work we address the computational cancer spread quantification scenario in whole body FDG-PET/CT scans. At the static level, this setting can be modeled as a clustering problem on the set of 3D connected components of the whole body PET tumoral segmentation mask carried out by nuclear medicine physicians. At the dynamic level, and ad-hoc algorithm is proposed in order to quantify the cancer spread time evolution which, when combined with other existing indicators, gives rise to the metabolic tumor volume-aggressiveness-spread time evolution chart, a novel tool that we claim that would prove useful in nuclear medicine and oncological clinical or research scenarios. Good performance results of the proposed methodologies both at the clinical and technological level are shown using a dataset of 48 segmented whole body FDG-PET/CT scans.

Abstract: In this work we present the iterative multi-class multi-scale stacked sequential learning framework (IMMSSL), a novel learning scheme that is particularly suited for medical volume segmentation applications. This model exploits the inherent voxel contextual information of the structures of interest in order to improve its segmentation performance results. Without any feature set or learning algorithm prior assumption, the proposed scheme directly seeks to learn the contextual properties of a region from the predicted classifications of previous classifiers within an iterative scheme. Performance results regarding segmentation accuracy in three two-class and multi-class medical volume datasets show a significant improvement with respect to state of the art alternatives. Due to its easiness of implementation and its independence of feature space and learning algorithm, the presented machine learning framework could be taken into consideration as a first choice in complex volume segmentation scenarios.

Abstract: Human multi-limb segmentation in RGB images has attracted a lot of interest in the research community because of the huge amount of possible applications in fields like Human-Computer Interaction, Surveillance, eHealth, or Gaming. Nevertheless, human multi-limb segmentation is a very hard task because of the changes in appearance produced by different points of view, clothing, lighting conditions, occlusions, and number of articulations of the human body. Furthermore, this huge pose variability makes the availability of large annotated datasets difficult. In this paper, we introduce the HuPBA8k+ dataset. The dataset contains more than 8000 labeled frames at pixel precision, including more than 120000 manually labeled samples of 14 different limbs. For completeness, the dataset is also labeled at frame-level with action annotations drawn from an 11 action dictionary which includes both single person actions and person-person interactive actions. Furthermore, we also propose a two-stage approach for the segmentation of human limbs. In a first stage, human limbs are trained using cascades of classifiers to be split in a tree-structure way, which is included in an Error-Correcting Output Codes (ECOC) framework to define a body-like probability map. This map is used to obtain a binary mask of the subject by means of GMM color modelling and GraphCuts theory. In a second stage, we embed a similar tree-structure in an ECOC framework to build a more accurate set of limb-like probability maps within the segmented user mask, that are fed to a multi-label GraphCut procedure to obtain final multi-limb segmentation. The methodology is tested on the novel HuPBA8k+ dataset, showing performance improvements in comparison to state-of-the-art approaches. In addition, a baseline of standard action recognition methods for the 11 actions categories of the novel dataset is also provided.

Abstract: The visual analysis of humans from images is an important topic of interest due to its relevance to many computer vision applications like pedestrian detection, monitoring and surveillance, human-computer interaction, e-health or content-based image retrieval, among others.
In this dissertation we are interested in learning different visual representations of the human body that are helpful for the visual analysis of humans in images and video sequences. To that end, we analyze both RGB and depth image modalities and address the problem from three different research lines, at different levels of abstraction; from pixels to gestures: human segmentation, human pose estimation and gesture recognition.
First, we show how binary segmentation (object vs. background) of the human body in image sequences is helpful to remove all the background clutter present in the scene. The presented method, based on Graph cuts optimization, enforces spatio-temporal consistency of the produced segmentation masks among consecutive frames. Secondly, we present a framework for multi-label segmentation for obtaining much more detailed segmentation masks: instead of just obtaining a binary representation separating the human body from the background, finer segmentation masks can be obtained separating the different body parts.
At a higher level of abstraction, we aim for a simpler yet descriptive representation of the human body. Human pose estimation methods usually rely on skeletal models of the human body, formed by segments (or rectangles) that represent the body limbs, appropriately connected following the kinematic constraints of the human body. In practice, such skeletal models must fulfill some constraints in order to allow for efficient inference, while actually limiting the expressiveness of the model. In order to cope with this, we introduce a top-down approach for predicting the position of the body parts in the model, using a mid-level part representation based on Poselets.
Finally, we propose a framework for gesture recognition based on the bag of visual words framework. We leverage the benefits of RGB and depth image modalities by combining modality-specific visual vocabularies in a late fusion fashion. A new rotation-variant depth descriptor is presented, yielding better results than other state-of-the-art descriptors. Moreover, spatio-temporal pyramids are used to encode rough spatial and temporal structure. In addition, we present a probabilistic reformulation of Dynamic Time Warping for gesture segmentation in video sequences. A Gaussian-based probabilistic model of a gesture is learnt, implicitly encoding possible deformations in both spatial and time domains.