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Author | Frederic Sampedro; Sergio Escalera; Anna Domenech; Ignasi Carrio | ||||
Title | A computational framework for cancer response assessment based on oncological PET-CT scans | Type | Journal Article | ||
Year | 2014 | Publication | Computers in Biology and Medicine | Abbreviated Journal | CBM |
Volume | 55 | Issue | Pages | 92–99 | |
Keywords | Computer aided diagnosis; Nuclear medicine; Machine learning; Image processing; Quantitative analysis | ||||
Abstract | In this work we present a comprehensive computational framework to help in the clinical assessment of cancer response from a pair of time consecutive oncological PET-CT scans. In this scenario, the design and implementation of a supervised machine learning system to predict and quantify cancer progression or response conditions by introducing a novel feature set that models the underlying clinical context is described. Performance results in 100 clinical cases (corresponding to 200 whole body PET-CT scans) in comparing expert-based visual analysis and classifier decision making show up to 70% accuracy within a completely automatic pipeline and 90% accuracy when providing the system with expert-guided PET tumor segmentation masks. | ||||
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Notes | HuPBA;MILAB | Approved | no | ||
Call Number | Admin @ si @ SED2014 | Serial | 2606 | ||
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