Laura Igual, Joan Carles Soliva, Roger Gimeno, Sergio Escalera, Oscar Vilarroya, & Petia Radeva. (2012). Automatic Internal Segmentation of Caudate Nucleus for Diagnosis of Attention Deficit Hyperactivity Disorder. In 9th International Conference on Image Analysis and Recognition (Vol. 7325, pp. 222–229). LNCS.
Abstract: Poster
Studies on volumetric brain Magnetic Resonance Imaging (MRI) showed neuroanatomical abnormalities in pediatric Attention-Deficit/Hyperactivity Disorder (ADHD). In particular, the diminished right caudate volume is one of the most replicated findings among ADHD samples in morphometric MRI studies. In this paper, we propose a fully-automatic method for internal caudate nucleus segmentation based on machine learning. Moreover, the ratio between right caudate body volume and the bilateral caudate body volume is applied in a ADHD diagnostic test. We separately validate the automatic internal segmentation of caudate in head and body structures and the diagnostic test using real data from ADHD and control subjects. As a result, we show accurate internal caudate segmentation and similar performance among the proposed automatic diagnostic test and the manual annotation.
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