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| Author | Jaume Garcia | ||||
| Title | Statistical Models of the Architecture and Function of the Left Ventricle | Type | Book Whole | ||
| Year | 2009 | Publication | PhD Thesis, Universitat Autonoma de Barcelona-CVC | Abbreviated Journal | |
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| Abstract | Cardiovascular Diseases, specially those affecting the Left Ventricle (LV), are the leading cause of death in developed countries with approximately a 30% of all global deaths. In order to address this public health concern, physicians focus on diagnosis and therapy planning. On one hand, early and accurate detection of Regional Wall Motion Abnormalities (RWMA) significantly contributes to a quick diagnosis and prevents the patient to reach more severe stages. On the other hand, a thouroughly knowledge of the normal gross anatomy of the LV, as well as, the distribution of its muscular fibers is crucial for designing specific interventions and therapies (such as pacemaker implanction). Statistical models obtained from the analysis of different imaging modalities allow the computation of the normal ranges of variation within a given population. Normality models are a valuable tool for the definition of objective criterions quantifying the degree of (anomalous) deviation of the LV function and anatomy for a given subject. The creation of statistical models involve addressing three main issues: extraction of data from images, definition of a common domain for comparison of data across patients and designing appropriate statistical analysis schemes. In this PhD thesis we present generic image processing tools for the creation of statistical models of the LV anatomy and function. On one hand, we use differential geometry concepts to define a computational framework (the Normalized Parametric Domain, NPD) suitable for the comparison and fusion of several clinical scores obtained over the LV. On the other hand, we present a variational approach (the Harmonic Phase Flow, HPF) for the estimation of myocardial motion that provides dense and continuous vector fields without overestimating motion at injured areas. These tools are used for the creation of statistical models. Regarding anatomy, we obtain an atlas jointly modelling, both, LV gross anatomy and fiber architecture. Regarding function, we compute normality patterns of scores characterizing the (global and local) LV function and explore, for the first time, the configuration of local scores better suited for RWMA detection. | ||||
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| Corporate Author | Thesis | Ph.D. thesis | |||
| Publisher | Ediciones Graficas Rey | Place of Publication | Editor | Debora Gil | |
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| Notes | IAM | Approved | no | ||
| Call Number | IAM @ iam @ Gar2009a | Serial | 1499 | ||
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| Author | Jaume Garcia; Debora Gil; Francesc Carreras; Sandra Pujades; R.Leta; Xavier Alomar; Guillem Pons-LLados | ||||
| Title | Patrons de Normalitat Regional per la Valoració de la Funció del Ventricle Esquerre | Type | Conference Article | ||
| Year | 2008 | Publication | XX Congrés de la Societat Catalana de Cardiologia | Abbreviated Journal | |
| Volume | Issue | Pages | 60 | ||
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| Abstract | Les malalties cardiovasculars afecten les propietats contràctils de la banda ventricular i provoquen una variació de la funció del Ventricle Esquerre (VE) . Només els indicadors locals (strains, la deformació del teixit) són capaços de detectar anomalies en territoris específics del VE . Patrons de normalitat regionals d’aquests paràmetres serien d’utilitat a l’hora de valorar-ne la funció .
Presentem un Domini Paramètric Normalitzat (DPN) que permet comparar dades de diferents pacients i definir Patrons de Normalitat Regional (PNR) |
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| Publisher | Place of Publication | Barcelona | Editor | ||
| Language | catalan | Summary Language | catalan | Original Title | |
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| Notes | IAM; | Approved | no | ||
| Call Number | IAM @ iam @ GGC2008b | Serial | 1503 | ||
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| Author | Jaume Garcia; Debora Gil; Francesc Carreras ; Sandra Pujades; R.Leta; Xavier Alomar; Guillem Pons-LLados | ||||
| Title | Un Model 3D del Ventricle Esquerre Integrant Anatomia i Funcionalitat | Type | Conference Article | ||
| Year | 2008 | Publication | XX Congrés de la Societat Catalana de Cardiologia, Actes del Congres | Abbreviated Journal | |
| Volume | Issue | Pages | 122 | ||
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| Abstract | Els canvis en la dinàmica del Ventricle Esquerre (VE) reflecteixen la majoria de malalties cardiovasculars . Els avenços en imatge mèdica han impulsat la recerca en models i simulacions de la dinàmica 3D del VE . La majoria dels models existents sols consideren l’anatomia externa del VE i no permeten una avaluació de l’acoblament electromecànic . Donat que la mecànica d’un muscle depèn de la orientació de les seves fibres, un model realista hauria d’incloure la disposició espacial de la banda ventricular helicoidal (BVH) .
Proposem desenvolupar un model del VE adaptat a cada pacient que integri, per primer cop, l’anatomia de la banda ventricular, l’anatomia externa del VE i la seva funcionalitat, per a una millor determinació del patró d’activació electromecànica |
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| Publisher | Place of Publication | Barcelona | Editor | ||
| Language | catalan | Summary Language | catalan | Original Title | |
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| Notes | IAM | Approved | no | ||
| Call Number | IAM @ iam @ GGC2008c | Serial | 1504 | ||
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| Author | Jaume Garcia; Debora Gil; Francesc Carreras; Sandra Pujades; R.Leta | ||||
| Title | Modelització 4-Dimensional de la Funció Siatólica del Ventricle Esquerre | Type | Conference Article | ||
| Year | 2007 | Publication | XIX Congrés de la Societat Catalana de Cardiologia de Barcelona | Abbreviated Journal | |
| Volume | Issue | Pages | 133-134 | ||
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| Abstract | L’evolució tecnològica en el tractament de les imatges mèdiques permet reconstruir, amb el software apropiat, imatges tridimensionals de les estructures cardiovasculars i dotar-les de moviment. Les imatges 4D resultants faciliten l’estudi de la fisiopatologia de la insuficiència cardíaca en base als transtorns de l’activació electromecànica ventricular, el que pot ser d’interès en el procés de selecció de pacients candidats a teràpies de resincronització. Presentem els resultats preliminars de la reconstrucció 4D del ventricle esquerre (VE) a partir de les seqüències de tagging miocàrdic del VE. | ||||
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| Publisher | Place of Publication | Barcelona (Spain) | Editor | ||
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| Notes | IAM | Approved | no | ||
| Call Number | IAM @ iam @ GGC2007 | Serial | 1505 | ||
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| Author | Jaume Garcia; Debora Gil; Luis Badiella; Aura Hernandez-Sabate; Francesc Carreras; Sandra Pujades; Enric Marti | ||||
| Title | A Normalized Framework for the Design of Feature Spaces Assessing the Left Ventricular Function | Type | Journal Article | ||
| Year | 2010 | Publication | IEEE Transactions on Medical Imaging | Abbreviated Journal | TMI |
| Volume | 29 | Issue | 3 | Pages | 733-745 |
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| Abstract | A through description of the left ventricle functionality requires combining complementary regional scores. A main limitation is the lack of multiparametric normality models oriented to the assessment of regional wall motion abnormalities (RWMA). This paper covers two main topics involved in RWMA assessment. We propose a general framework allowing the fusion and comparison across subjects of different regional scores. Our framework is used to explore which combination of regional scores (including 2-D motion and strains) is better suited for RWMA detection. Our statistical analysis indicates that for a proper (within interobserver variability) identification of RWMA, models should consider motion and extreme strains. | ||||
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| ISSN | 0278-0062 | ISBN | Medium | ||
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| Notes | IAM | Approved | no | ||
| Call Number | IAM @ iam @ GGH2010b | Serial | 1507 | ||
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| Author | Jaume Garcia; Debora Gil; A.Bajo; M.J.Ledesma-Carbayo; C.SantaMarta | ||||
| Title | Influence of the temporal resolution on the quantification of displacement fields in cardiac magnetic resonance tagged images | Type | Conference Article | ||
| Year | 2008 | Publication | Proc. Computers in Cardiology | Abbreviated Journal | |
| Volume | 35 | Issue | Pages | 785-788 | |
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| Abstract | It is difficult to acquire tagged cardiac MR images with a high temporal and spatial resolution using clinical MR scanners. However, if such images are used for quantifying scores based on motion, it is essential a resolution as high as possible. This paper explores the influence of the temporal resolution of a tagged series on the quantification of myocardial dynamic parameters. To such purpose we have designed a SPAMM (Spatial Modulation of Magnetization) sequence allowing acquisition of sequences at simple and double temporal resolution. Sequences are processed to compute myocardial motion by an automatic technique based on the tracking of the harmonic phase of tagged images (the Harmonic Phase Flow, HPF). The results have been compared to manual tracking of myocardial tags. The error in displacement fields for double resolution sequences reduces 17%. | ||||
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| Publisher | Place of Publication | Editor | Alan Murray | ||
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| Notes | IAM | Approved | no | ||
| Call Number | IAM @ iam @ GGB2008 | Serial | 1508 | ||
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| Author | Jaume Garcia; Debora Gil; Joel Barajas; Francesc Carreras; Sandra Pujades; Petia Radeva | ||||
| Title | Characterization of ventricular torsion in healthy subjects using Gabor filters and a variational framework | Type | Conference Article | ||
| Year | 2006 | Publication | Proc. Computers in Cardiology | Abbreviated Journal | |
| Volume | Issue | Pages | 877-880 | ||
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| Abstract | In this work, we present a fully automated method for tissue deformation estimation in tagged magnetic resonance images (TMRI). Gabor filter banks, tuned independently for each left ventricle level, provide optimally filtered complex images which phase remains constant along the cardiac cycle. This fact can be thought as the brightness constancy condition required by classical optical flow (OF) methods. Pairs of these filtered sequences, together with a variational formulation are used in a second step to obtain dense continuous deformation maps that we call Harmonic Phase Flow. This method has been used to determine reference values of ventricular torsion (VT) in a set of 8 healthy volunteers. The results encourage the use of VT as a useful parameter for ventricular function assessment in clinical routine. | ||||
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| Notes | IAM;MILAB | Approved | no | ||
| Call Number | IAM @ iam @ GGB2006a | Serial | 1509 | ||
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| Author | Jaume Garcia; Francesc Carreras; Sandra Pujades; Debora Gil | ||||
| Title | Regional motion patterns for the Left Ventricle function assessment | Type | Conference Article | ||
| Year | 2008 | Publication | Proc. 19th Int. Conf. Pattern Recognition ICPR 2008 | Abbreviated Journal | |
| Volume | Issue | Pages | 1-4 | ||
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| Abstract | Regional scores (e.g. strain, perfusion) of the Left Ventricle (LV) functionality are playing an increasing role in the diagnosis of cardiac diseases. A main limitation is the lack of normality models for complementary scores oriented to assessment of the LV integrity. This paper introduces an original framework based on a parametrization of the LV domain, which allows comparison across subjects of local physiological measures of different nature. We compute regional normality patterns in a feature space characterizing the LV function. We show the consistency of the model for the regional motion on healthy and hypokinetic pathological cases | ||||
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| Notes | IAM | Approved | no | ||
| Call Number | IAM @ iam @ GCP2008 | Serial | 1510 | ||
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| Author | Jaume Garcia; David Rotger; Francesc Carreras; R.Leta; Petia Radeva | ||||
| Title | Contrast echography segmentation and tracking by trained deformable models | Type | Conference Article | ||
| Year | 2003 | Publication | Proc. Computers in Cardiology | Abbreviated Journal | |
| Volume | 30 | Issue | Pages | 173-176 | |
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| Abstract | The objective of this work is to segment the human left ventricle myocardium (LVM) in contrast echocardiography imaging and thus track it along a cardiac cycle in order to extract quantitative data about heart function. Ultrasound images are hard to work with due to their speckle appearance. To overcome this we report the combination of active contour models (ACM) or snakes and active shape models (ASM). The ability of ACM in giving closed and smooth curves in addition to the power of the ASM in producing shapes similar to the ones learned, evoke to a robust algorithm. Meanwhile the snake is attracted towards image main features, ASM acts as a correction factor. The algorithm was tested independently on 180 frames and satisfying results were obtained: in 95% the maximum difference between automatic and experts segmentation was less than 12 pixels. | ||||
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| Publisher | Place of Publication | Centre de Visió per Computador – Dept. Informàtica, UAB Edifici O – Campus UAB, 08193 Bellater | Editor | ||
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| ISSN | 0276-6547 | ISBN | 0-7803-8170-X | Medium | |
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| Notes | IAM;MILAB | Approved | no | ||
| Call Number | IAM @ iam @ GRC2003 | Serial | 1512 | ||
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| Author | Jaume Garcia; Albert Andaluz; Debora Gil; Francesc Carreras | ||||
| Title | Decoupled External Forces in a Predictor-Corrector Segmentation Scheme for LV Contours in Tagged MR Images | Type | Conference Article | ||
| Year | 2010 | Publication | 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society | Abbreviated Journal | |
| Volume | Issue | Pages | 4805-4808 | ||
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| Abstract | Computation of functional regional scores requires proper identification of LV contours. On one hand, manual segmentation is robust, but it is time consuming and requires high expertise. On the other hand, the tag pattern in TMR sequences is a problem for automatic segmentation of LV boundaries. We propose a segmentation method based on a predictorcorrector (Active Contours – Shape Models) scheme. Special stress is put in the definition of the AC external forces. First, we introduce a semantic description of the LV that discriminates myocardial tissue by using texture and motion descriptors. Second, in order to ensure convergence regardless of the initial contour, the external energy is decoupled according to the orientation of the edges in the image potential. We have validated the model in terms of error in segmented contours and accuracy of regional clinical scores. | ||||
| Address | Buenos Aires (Argentina) | ||||
| Corporate Author | IEEE EMB | Thesis | |||
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| ISSN | 1557-170X | ISBN | 978-1-4244-4123-5 | Medium | |
| Area | Expedition | Conference | EMBC | ||
| Notes | IAM | Approved | no | ||
| Call Number | IAM @ iam @ GAG2010 | Serial | 1514 | ||
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| Author | Jaume Garcia; Debora Gil; Aura Hernandez-Sabate | ||||
| Title | Endowing Canonical Geometries to Cardiac Structures | Type | Book Chapter | ||
| Year | 2010 | Publication | Statistical Atlases And Computational Models Of The Heart | Abbreviated Journal | |
| Volume | 6364 | Issue | Pages | 124-133 | |
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| Abstract | International conference on Cardiac electrophysiological simulation challenge
In this paper, we show that canonical (shape-based) geometries can be endowed to cardiac structures using tubular coordinates defined over their medial axis. We give an analytic formulation of these geometries by means of B-Splines. Since B-Splines present vector space structure PCA can be applied to their control points and statistical models relating boundaries and the interior of the anatomical structures can be derived. We demonstrate the applicability in two cardiac structures, the 3D Left Ventricular volume, and the 2D Left-Right ventricle set in 2D Short Axis view. |
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| Publisher | Springer Berlin / Heidelberg | Place of Publication | Editor | Camara, O.; Pop, M.; Rhode, K.; Sermesant, M.; Smith, N.; Young, A. | |
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| Series Editor | Series Title | Lecture Notes in Computer Science | Abbreviated Series Title | LNCS | |
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| Notes | IAM | Approved | no | ||
| Call Number | IAM @ iam @ GGH2010b | Serial | 1515 | ||
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| Author | M.Gomez; Josefina Mauri; Eduard Fernandez-Nofrerias; Oriol Rodriguez-Leon; Carme Julia; Debora Gil; Petia Radeva | ||||
| Title | Reconstrucción de un modelo espacio-temporal de la luz del vaso a partir de secuencias de ecografía intracoronaria | Type | Conference Article | ||
| Year | 2002 | Publication | XXXVIII Congreso Nacional de la Sociedad Española de Cardiología. | Abbreviated Journal | |
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| Notes | IAM;ADAS;MILAB | Approved | no | ||
| Call Number | IAM @ iam @ GMF2002d | Serial | 1516 | ||
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| Author | Debora Gil | ||||
| Title | Geometric Differential Operators for Shape Modelling | Type | Book Whole | ||
| Year | 2004 | Publication | PhD Thesis, Universitat Autonoma de Barcelona-CVC | Abbreviated Journal | |
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| Abstract | Medical imaging feeds research in many computer vision and image processing fields: image filtering, segmentation, shape recovery, registration, retrieval and pattern matching. Because of their low contrast changes and large variety of artifacts and noise, medical imaging processing techniques relying on an analysis of the geometry of image level sets rather than on intensity values result in more robust treatment. From the starting point of treatment of intravascular images, this PhD thesis ad- dresses the design of differential image operators based on geometric principles for a robust shape modelling and restoration. Among all fields applying shape recovery, we approach filtering and segmentation of image objects. For a successful use in real images, the segmentation process should go through three stages: noise removing, shape modelling and shape recovery. This PhD addresses all three topics, but for the sake of algorithms as automated as possible, techniques for image processing will be designed to satisfy three main principles: a) convergence of the iterative schemes to non-trivial states avoiding image degeneration to a constant image and representing smooth models of the originals; b) smooth asymptotic behav- ior ensuring stabilization of the iterative process; c) fixed parameter values ensuring equal (domain free) performance of the algorithms whatever initial images/shapes. Our geometric approach to the generic equations that model the different processes approached enables defining techniques satisfying all the former requirements. First, we introduce a new curvature-based geometric flow for image filtering achieving a good compromise between noise removing and resemblance to original images. Sec- ond, we describe a new family of diffusion operators that restrict their scope to image level curves and serve to restore smooth closed models from unconnected sets of points. Finally, we design a regularization of snake (distance) maps that ensures its smooth convergence towards any closed shape. Experiments show that performance of the techniques proposed overpasses that of state-of-the-art algorithms. | ||||
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| Corporate Author | Thesis | Ph.D. thesis | |||
| Publisher | Ediciones Graficas Rey | Place of Publication | Barcelona (Spain) | Editor | Jordi Saludes i Closa;Petia Radeva |
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| ISSN | ISBN | 84-933652-0-3 | Medium | prit | |
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| Notes | IAM; | Approved | no | ||
| Call Number | IAM @ iam @ GIL2004 | Serial | 1517 | ||
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| Author | Debora Gil | ||||
| Title | Regularized Curvature Flow | Type | Report | ||
| Year | 2002 | Publication | CVC Technical Report | Abbreviated Journal | |
| Volume | Issue | 63 | Pages | ||
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| Publisher | Computer Vision Centre | Place of Publication | Editor | ||
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| Notes | IAM; | Approved | no | ||
| Call Number | IAM @ iam @ Gil2002 | Serial | 1518 | ||
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| Author | Debora Gil; Jaume Garcia; Aura Hernandez-Sabate; Enric Marti | ||||
| Title | Manifold parametrization of the left ventricle for a statistical modelling of its complete anatomy | Type | Conference Article | ||
| Year | 2010 | Publication | 8th Medical Imaging | Abbreviated Journal | |
| Volume | 7623 | Issue | 762304 | Pages | 304 |
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| Abstract | Distortion of Left Ventricle (LV) external anatomy is related to some dysfunctions, such as hypertrophy. The architecture of myocardial fibers determines LV electromechanical activation patterns as well as mechanics. Thus, their joined modelling would allow the design of specific interventions (such as peacemaker implantation and LV remodelling) and therapies (such as resynchronization). On one hand, accurate modelling of external anatomy requires either a dense sampling or a continuous infinite dimensional approach, which requires non-Euclidean statistics. On the other hand, computation of fiber models requires statistics on Riemannian spaces. Most approaches compute separate statistical models for external anatomy and fibers architecture. In this work we propose a general mathematical framework based on differential geometry concepts for computing a statistical model including, both, external and fiber anatomy. Our framework provides a continuous approach to external anatomy supporting standard statistics. We also provide a straightforward formula for the computation of the Riemannian fiber statistics. We have applied our methodology to the computation of complete anatomical atlas of canine hearts from diffusion tensor studies. The orientation of fibers over the average external geometry agrees with the segmental description of orientations reported in the literature. | ||||
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| Publisher | SPIE | Place of Publication | Editor | ||
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| Area | Expedition | Conference | SPIE | ||
| Notes | IAM | Approved | no | ||
| Call Number | IAM @ iam @ GGH2010a | Serial | 1522 | ||
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