Abstract: Intravascular ultrasound (IVUS) represents a powerful imaging technique to explore coronary vessels and to study their morphology and histologic properties. In this paper, we characterize different tissues based on radial frequency, texture-based, and combined features. To deal with the classification of multiple tissues, we require the use of robust multi-class learning techniques. In this sense, error-correcting output codes (ECOC) show to robustly combine binary classifiers to solve multi-class problems. In this context, we propose a strategy to model multi-class classification tasks using sub-classes information in the ECOC framework. The new strategy splits the classes into different sub-sets according to the applied base classifier. Complex IVUS data sets containing overlapping data are learnt by splitting the original set of classes into sub-classes, and embedding the binary problems in a problem-dependent ECOC design. The method automatically characterizes different tissues, showing performance improvements over the state-of-the-art ECOC techniques for different base classifiers. Furthermore, the combination of RF and texture-based features also shows improvements over the state-of-the-art approaches.

Abstract: An efficient method to overcome adverse effects of occlusion upon object tracking is presented. The method is based on matching paths of objects in time and solves a complex occlusion-caused problem of merging separate segments of the same path.

Abstract: Three-dimensional intravascular ultrasound (IVUS) allows to visualize and obtain volumetric measurements of coronary lesions through an exploration of the cross sections and longitudinal views of arteries. However, the visualization and subsequent morpho-geometric measurements in IVUS longitudinal cuts are subject to distortion caused by periodic image/vessel motion around the IVUS catheter. Usually, to overcome the image motion artifact ECG-gating and image-gated approaches are proposed, leading to slowing the pullback acquisition or disregarding part of IVUS data. In this paper, we argue that the image motion is due to 3-D vessel geometry as well as cardiac dynamics, and propose a dynamic model based on the tracking of an elliptical vessel approximation to recover the rigid transformation and align IVUS images without loosing any IVUS data. We report an extensive validation with synthetic simulated data and in vivo IVUS sequences of 30 patients achieving an average reduction of the image artifact of 97% in synthetic data and 79% in real-data. Our study shows that IVUS alignment improves longitudinal analysis of the IVUS data and is a necessary step towards accurate reconstruction and volumetric measurements of 3-D IVUS.

Abstract: The Diagnosis of Left Ventricle (LV) pathologies is related to regional wall motion analysis. Health indicator scores such as the rotation and the torsion are useful for the diagnose of the Left Ventricle (LV) function. However, this requires proper identification of LV segments. On one hand, manual segmentation is robust, but it is slow and requires medical expertise. On the other hand, the tag pattern in Tagged Magnetic Resonance (TMR) sequences is a problem for the automatic segmentation of the LV boundaries. Consequently, we propose a method based in the classical formulation of parametric Snakes, combined with Active Shape models. Our semantic definition of the LV is tagged tissue that experiences motion in the systolic cycle. This defines two energy potentials for the Snake convergence. Additionally, the mean shape corrects excessive deviation from the anatomical shape. We have validated our approach in 15 healthy volunteers and two short axis cuts. In this way, we have compared the automatic segmentations to manual shapes outlined by medical experts. Also, we have explored the accuracy of clinical scores computed using automatic contours. The results show minor divergence in the approximation and the manual segmentations as well as robust computation of clinical scores in all cases. From this we conclude that the proposed method is a promising support tool for clinical analysis.

Abstract: The assessment of Myocardial Blush Grade after primary angioplasty is a precious diagnostic tool to understand if the patient needs further medication or the use of specifics drugs. Unfortunately, the assessment of MBG is difficult for non highly specialized staff. Experimental data show that there is poor correlation between MBG assessment of low and high specialized staff, thus reducing its applicability. This paper proposes a method able to achieve an objective measure of MBG, or a set of parameters that correlates with the MBG. The method tracks the blush area starting from just one single frame tagged by the physician. As a consequence, the blush area is kept isolated from contaminating phenomena such as diaphragm and arteries movements. We also present a method to extract four parameters that are expected to correlate with the MBG. Preliminary results show that the method is capable of extracting interesting information regarding the behavior of the myocardial perfusion.

Abstract: Color is a powerful visual cue for many computer vision applications such as image segmentation and object recognition. However, most of the existing color models depend on the imaging conditions affecting negatively the performance of the task at hand. Often, a reflection model (e.g., Lambertian or dichromatic reflectance) is used to derive color invariant models. However, those reflection models might be too restricted to model real-world scenes in which different reflectance mechanisms may hold simultaneously. Therefore, in this paper, we aim to derive color invariance by learning from color models to obtain diversified color invariant ensembles. First, a photometrical orthogonal and non-redundant color model set is taken on input composed of both color variants and invariants. Then, the proposed method combines and weights these color models to arrive at a diversified color ensemble yielding a proper balance between invariance (repeatability) and discriminative power (distinctiveness). To achieve this, the fusion method uses a multi-view approach to minimize the estimation error. In this way, the method is robust to data uncertainty and produces properly diversified color invariant ensembles. Experiments are conducted on three different image datasets to validate the method. From the theoretical and experimental results, it is concluded that the method is robust against severe variations in imaging conditions. The method is not restricted to a certain reflection model or parameter tuning. Further, the method outperforms state-of- the-art detection techniques in the field of object, skin and road recognition.

Abstract: The median graph has been shown to be a good choice to infer a representative of a set of graphs. It has been successfully applied to graph-based classification and clustering. Nevertheless, its computation is extremely complex. Several approaches have been presented up to now based on different strategies. In this paper we present a new approximate recursive algorithm for median graph computation based on graph embedding into vector spaces. Preliminary experiments on three databases show that this new approach is able to obtain better medians than the previous existing approaches.

Abstract: Document classification usually requires of structural features such as the physical layout to obtain good accuracy rates on complex documents. This paper introduces a descriptor of the layout and a distance measure based on the cyclic dynamic time warping which can be computed in O(n2). This descriptor is translation invariant and can be easily modified to be scale and rotation invariant. Experiments with this descriptor and its rotation invariant modification are performed on the Girona archives database and compared against another common layout distance, the minimum weight edge cover. The experiments show that these methods outperform the MWEC both in accuracy and speed, particularly on rotated documents.