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Author Jaume Garcia; Albert Andaluz; Debora Gil; Francesc Carreras
Title Decoupled External Forces in a Predictor-Corrector Segmentation Scheme for LV Contours in Tagged MR Images Type Conference Article
Year 2010 Publication 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society Abbreviated Journal
Volume Issue Pages 4805-4808
Keywords
Abstract Computation of functional regional scores requires proper identification of LV contours. On one hand, manual segmentation is robust, but it is time consuming and requires high expertise. On the other hand, the tag pattern in TMR sequences is a problem for automatic segmentation of LV boundaries. We propose a segmentation method based on a predictorcorrector (Active Contours – Shape Models) scheme. Special stress is put in the definition of the AC external forces. First, we introduce a semantic description of the LV that discriminates myocardial tissue by using texture and motion descriptors. Second, in order to ensure convergence regardless of the initial contour, the external energy is decoupled according to the orientation of the edges in the image potential. We have validated the model in terms of error in segmented contours and accuracy of regional clinical scores.
Address Buenos Aires (Argentina)
Corporate Author IEEE EMB Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1557-170X ISBN 978-1-4244-4123-5 Medium
Area Expedition (down) Conference EMBC
Notes IAM Approved no
Call Number IAM @ iam @ GAG2010 Serial 1514
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Author Jaume Garcia; Debora Gil; Aura Hernandez-Sabate
Title Endowing Canonical Geometries to Cardiac Structures Type Book Chapter
Year 2010 Publication Statistical Atlases And Computational Models Of The Heart Abbreviated Journal
Volume 6364 Issue Pages 124-133
Keywords
Abstract International conference on Cardiac electrophysiological simulation challenge
In this paper, we show that canonical (shape-based) geometries can be endowed to cardiac structures using tubular coordinates defined over their medial axis. We give an analytic formulation of these geometries by means of B-Splines. Since B-Splines present vector space structure PCA can be applied to their control points and statistical models relating boundaries and the interior of the anatomical structures can be derived. We demonstrate the applicability in two cardiac structures, the 3D Left Ventricular volume, and the 2D Left-Right ventricle set in 2D Short Axis view.
Address
Corporate Author Thesis
Publisher Springer Berlin / Heidelberg Place of Publication Editor Camara, O.; Pop, M.; Rhode, K.; Sermesant, M.; Smith, N.; Young, A.
Language Summary Language Original Title
Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition (down) Conference
Notes IAM Approved no
Call Number IAM @ iam @ GGH2010b Serial 1515
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Author M.Gomez; Josefina Mauri; Eduard Fernandez-Nofrerias; Oriol Rodriguez-Leon; Carme Julia; Debora Gil; Petia Radeva
Title Reconstrucción de un modelo espacio-temporal de la luz del vaso a partir de secuencias de ecografía intracoronaria Type Conference Article
Year 2002 Publication XXXVIII Congreso Nacional de la Sociedad Española de Cardiología. Abbreviated Journal
Volume Issue Pages
Keywords
Abstract
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition (down) Conference
Notes IAM;ADAS;MILAB Approved no
Call Number IAM @ iam @ GMF2002d Serial 1516
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Author Debora Gil
Title Geometric Differential Operators for Shape Modelling Type Book Whole
Year 2004 Publication PhD Thesis, Universitat Autonoma de Barcelona-CVC Abbreviated Journal
Volume Issue Pages
Keywords
Abstract Medical imaging feeds research in many computer vision and image processing fields: image filtering, segmentation, shape recovery, registration, retrieval and pattern matching. Because of their low contrast changes and large variety of artifacts and noise, medical imaging processing techniques relying on an analysis of the geometry of image level sets rather than on intensity values result in more robust treatment. From the starting point of treatment of intravascular images, this PhD thesis ad- dresses the design of differential image operators based on geometric principles for a robust shape modelling and restoration. Among all fields applying shape recovery, we approach filtering and segmentation of image objects. For a successful use in real images, the segmentation process should go through three stages: noise removing, shape modelling and shape recovery. This PhD addresses all three topics, but for the sake of algorithms as automated as possible, techniques for image processing will be designed to satisfy three main principles: a) convergence of the iterative schemes to non-trivial states avoiding image degeneration to a constant image and representing smooth models of the originals; b) smooth asymptotic behav- ior ensuring stabilization of the iterative process; c) fixed parameter values ensuring equal (domain free) performance of the algorithms whatever initial images/shapes. Our geometric approach to the generic equations that model the different processes approached enables defining techniques satisfying all the former requirements. First, we introduce a new curvature-based geometric flow for image filtering achieving a good compromise between noise removing and resemblance to original images. Sec- ond, we describe a new family of diffusion operators that restrict their scope to image level curves and serve to restore smooth closed models from unconnected sets of points. Finally, we design a regularization of snake (distance) maps that ensures its smooth convergence towards any closed shape. Experiments show that performance of the techniques proposed overpasses that of state-of-the-art algorithms.
Address
Corporate Author Thesis Ph.D. thesis
Publisher Ediciones Graficas Rey Place of Publication Barcelona (Spain) Editor Jordi Saludes i Closa;Petia Radeva
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN 84-933652-0-3 Medium prit
Area Expedition (down) Conference
Notes IAM; Approved no
Call Number IAM @ iam @ GIL2004 Serial 1517
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Author Debora Gil
Title Regularized Curvature Flow Type Report
Year 2002 Publication CVC Technical Report Abbreviated Journal
Volume Issue 63 Pages
Keywords
Abstract
Address
Corporate Author Thesis
Publisher Computer Vision Centre Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition (down) Conference
Notes IAM; Approved no
Call Number IAM @ iam @ Gil2002 Serial 1518
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Author Debora Gil; Jose Maria-Carazo; Roberto Marabini
Title On the nature of 2D crystal unbending Type Journal Article
Year 2006 Publication Journal of Structural Biology Abbreviated Journal
Volume 156 Issue 3 Pages 546-555
Keywords Electron microscopy
Abstract Crystal unbending, the process that aims to recover a perfect crystal from experimental data, is one of the more important steps in electron crystallography image processing. The unbending process involves three steps: estimation of the unit cell displacements from their ideal positions, extension of the deformation field to the whole image and transformation of the image in order to recover an ideal crystal. In this work, we present a systematic analysis of the second step oriented to address two issues. First, whether the unit cells remain undistorted and only the distance between them should be changed (rigid case) or should be modified with the same deformation suffered by the whole crystal (elastic case). Second, the performance of different extension algorithms (interpolation versus approximation) is explored. Our experiments show that there is no difference between elastic and rigid cases or among the extension algorithms. This implies that the deformation fields are constant over large areas. Furthermore, our results indicate that the main source of error is the transformation of the crystal image.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1047-8477 ISBN Medium
Area Expedition (down) Conference
Notes IAM; Approved no
Call Number IAM @ iam @ GCM2006 Serial 1519
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Author Debora Gil; Jaume Garcia; Ruth Aris; Guillaume Houzeaux; Manuel Vazquez
Title A Riemmanian approach to cardiac fiber architecture modelling Type Conference Article
Year 2009 Publication 1st International Conference on Mathematical & Computational Biomedical Engineering Abbreviated Journal
Volume Issue Pages 59-62
Keywords cardiac fiber architecture; diffusion tensor magnetic resonance imaging; differential (Rie- mannian) geometry.
Abstract There is general consensus that myocardial fiber architecture should be modelled in order to fully understand the electromechanical properties of the Left Ventricle (LV). Diffusion Tensor magnetic resonance Imaging (DTI) is the reference image modality for rapid measurement of fiber orientations by means of the tensor principal eigenvectors. In this work, we present a mathematical framework for across subject comparison of the local geometry of the LV anatomy including the fiber architecture from the statistical analysis of DTI studies. We use concepts of differential geometry for defining a parametric domain suitable for statistical analysis of a low number of samples. We use Riemannian metrics to define a consistent computation of DTI principal eigenvector modes of variation. Our framework has been applied to build an atlas of the LV fiber architecture from 7 DTI normal canine hearts.
Address
Corporate Author Thesis
Publisher Place of Publication Swansea (UK) Editor Nithiarasu, R.L.R.V.L.
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition (down) Conference CMBE
Notes IAM Approved no
Call Number IAM @ iam @ FGA2009 Serial 1520
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Author Debora Gil; Jaume Garcia; Manuel Vazquez; Ruth Aris; Guillaume Houzeaux
Title Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function Type Conference Article
Year 2008 Publication 8th World Congress on Computational Mechanichs (WCCM8)/5th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) Abbreviated Journal
Volume Issue Pages
Keywords Left Ventricle; Electromechanical Models; Image Processing; Magnetic Resonance.
Abstract Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality . In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp. We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment. The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted. The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model.
Address
Corporate Author Thesis
Publisher Place of Publication Venezia (Italia) Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN B-31470-08 ISBN Medium
Area Expedition (down) Conference
Notes IAM Approved no
Call Number IAM @ iam @ GGV2008c Serial 1521
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Author Debora Gil; Jaume Garcia; Aura Hernandez-Sabate; Enric Marti
Title Manifold parametrization of the left ventricle for a statistical modelling of its complete anatomy Type Conference Article
Year 2010 Publication 8th Medical Imaging Abbreviated Journal
Volume 7623 Issue 762304 Pages 304
Keywords
Abstract Distortion of Left Ventricle (LV) external anatomy is related to some dysfunctions, such as hypertrophy. The architecture of myocardial fibers determines LV electromechanical activation patterns as well as mechanics. Thus, their joined modelling would allow the design of specific interventions (such as peacemaker implantation and LV remodelling) and therapies (such as resynchronization). On one hand, accurate modelling of external anatomy requires either a dense sampling or a continuous infinite dimensional approach, which requires non-Euclidean statistics. On the other hand, computation of fiber models requires statistics on Riemannian spaces. Most approaches compute separate statistical models for external anatomy and fibers architecture. In this work we propose a general mathematical framework based on differential geometry concepts for computing a statistical model including, both, external and fiber anatomy. Our framework provides a continuous approach to external anatomy supporting standard statistics. We also provide a straightforward formula for the computation of the Riemannian fiber statistics. We have applied our methodology to the computation of complete anatomical atlas of canine hearts from diffusion tensor studies. The orientation of fibers over the average external geometry agrees with the segmental description of orientations reported in the literature.
Address
Corporate Author Thesis
Publisher SPIE Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition (down) Conference SPIE
Notes IAM Approved no
Call Number IAM @ iam @ GGH2010a Serial 1522
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Author Debora Gil; Aura Hernandez-Sabate; Antoni Carol; Oriol Rodriguez; Petia Radeva
Title A Deterministic-Statistic Adventitia Detection in IVUS Images Type Conference Article
Year 2005 Publication ESC Congress Abbreviated Journal
Volume Issue Pages
Keywords Electron microscopy; Unbending; 2D crystal; Interpolation; Approximation
Abstract Plaque analysis in IVUS planes needs accurate intima and adventitia models. Large variety in adventitia descriptors difficulties its detection and motivates using a classification strategy for selecting points on the structure. Whatever the set of descriptors used, the selection stage suffers from fake responses due to noise and uncompleted true curves. In order to smooth background noise while strengthening responses, we apply a restricted anisotropic filter that homogenizes grey levels along the image significant structures. Candidate points are extracted by means of a simple semi supervised adaptive classification of the filtered image response to edge and calcium detectors. The final model is obtained by interpolating the former line segments with an anisotropic contour closing technique based on functional extension principles.
Address Stockholm; Sweden; September 2005
Corporate Author Thesis
Publisher Place of Publication ,Sweden (EU) Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition (down) Conference ESC
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ RMF2005a Serial 1523
Permanent link to this record
 

 
Author Debora Gil; Aura Hernandez-Sabate; Antoni Carol; Oriol Rodriguez; Petia Radeva
Title A Deterministic-Statistic Adventitia Detection in IVUS Images Type Conference Article
Year 2005 Publication 3rd International workshop on International Workshop on Functional Imaging and Modeling of the Heart Abbreviated Journal
Volume Issue Pages 65-74
Keywords Electron microscopy; Unbending; 2D crystal; Interpolation; Approximation
Abstract Plaque analysis in IVUS planes needs accurate intima and adventitia models. Large variety in adventitia descriptors difficulties its detection and motivates using a classification strategy for selecting points on the structure. Whatever the set of descriptors used, the selection stage suffers from fake responses due to noise and uncompleted true curves. In order to smooth background noise while strengthening responses, we apply a restricted anisotropic filter that homogenizes grey levels along the image significant structures. Candidate points are extracted by means of a simple semi supervised adaptive classification of the filtered image response to edge and calcium detectors. The final model is obtained by interpolating the former line segments with an anisotropic contour closing technique based on functional extension principles.
Address Barcelona; June 2005
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition (down) Conference FIMH
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ RMF2005 Serial 1524
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Author Debora Gil; Aura Hernandez-Sabate; Oriol Rodriguez; Josepa Mauri; Petia Radeva
Title Statistical Strategy for Anisotropic Adventitia Modelling in IVUS Type Journal Article
Year 2006 Publication IEEE Transactions on Medical Imaging Abbreviated Journal
Volume 25 Issue 6 Pages 768-778
Keywords Corners; T-junctions; Wavelets
Abstract Vessel plaque assessment by analysis of intravascular ultrasound sequences is a useful tool for cardiac disease diagnosis and intervention. Manual detection of luminal (inner) and mediaadventitia (external) vessel borders is the main activity of physicians in the process of lumen narrowing (plaque) quantification. Difficult definition of vessel border descriptors, as well as, shades, artifacts, and blurred signal response due to ultrasound physical properties trouble automated adventitia segmentation. In order to efficiently approach such a complex problem, we propose blending advanced anisotropic filtering operators and statistical classification techniques into a vessel border modelling strategy. Our systematic statistical analysis shows that the reported adventitia detection achieves an accuracy in the range of interobserver variability regardless of plaque nature, vessel geometry, and incomplete vessel borders. Index Terms–-Anisotropic processing, intravascular ultrasound (IVUS), vessel border segmentation, vessel structure classification.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition (down) Conference
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ GHR2006 Serial 1525
Permanent link to this record
 

 
Author Debora Gil; Aura Hernandez-Sabate; Mireia Brunat;Steven Jansen; Jordi Martinez-Vilalta
Title Structure-preserving smoothing of biomedical images Type Journal Article
Year 2011 Publication Pattern Recognition Abbreviated Journal PR
Volume 44 Issue 9 Pages 1842-1851
Keywords Non-linear smoothing; Differential geometry; Anatomical structures; segmentation; Cardiac magnetic resonance; Computerized tomography
Abstract Smoothing of biomedical images should preserve gray-level transitions between adjacent tissues, while restoring contours consistent with anatomical structures. Anisotropic diffusion operators are based on image appearance discontinuities (either local or contextual) and might fail at weak inter-tissue transitions. Meanwhile, the output of block-wise and morphological operations is prone to present a block structure due to the shape and size of the considered pixel neighborhood. In this contribution, we use differential geometry concepts to define a diffusion operator that restricts to image consistent level-sets. In this manner, the final state is a non-uniform intensity image presenting homogeneous inter-tissue transitions along anatomical structures, while smoothing intra-structure texture. Experiments on different types of medical images (magnetic resonance, computerized tomography) illustrate its benefit on a further process (such as segmentation) of images.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-3203 ISBN Medium
Area Expedition (down) Conference
Notes IAM; ADAS Approved no
Call Number IAM @ iam @ GHB2011 Serial 1526
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Author Debora Gil; Aura Hernandez-Sabate; Mireia Burnat; Steven Jansen; Jordi Martinez-Vilalta
Title Structure-Preserving Smoothing of Biomedical Images Type Conference Article
Year 2009 Publication 13th International Conference on Computer Analysis of Images and Patterns Abbreviated Journal
Volume 5702 Issue Pages 427-434
Keywords non-linear smoothing; differential geometry; anatomical structures segmentation; cardiac magnetic resonance; computerized tomography.
Abstract Smoothing of biomedical images should preserve gray-level transitions between adjacent tissues, while restoring contours consistent with anatomical structures. Anisotropic diffusion operators are based on image appearance discontinuities (either local or contextual) and might fail at weak inter-tissue transitions. Meanwhile, the output of block-wise and morphological operations is prone to present a block structure due to the shape and size of the considered pixel neighborhood. In this contribution, we use differential geometry concepts to define a diffusion operator that restricts to image consistent level-sets. In this manner, the final state is a non-uniform intensity image presenting homogeneous inter-tissue transitions along anatomical structures, while smoothing intra-structure texture. Experiments on different types of medical images (magnetic resonance, computerized tomography) illustrate its benefit on a further process (such as segmentation) of images.
Address Münster, Germany
Corporate Author Thesis
Publisher Springer Berlin Heidelberg Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title LNCS
Series Volume Series Issue Edition
ISSN 0302-9743 ISBN 978-3-642-03766-5 Medium
Area Expedition (down) Conference CAIP
Notes IAM Approved no
Call Number IAM @ iam @ GHB2009 Serial 1527
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Author Debora Gil; Oriol Rodriguez; Josepa Mauri; Petia Radeva
Title Statistical descriptors of the Myocardial perfusion in angiographic images Type Conference Article
Year 2006 Publication Proc. Computers in Cardiology Abbreviated Journal
Volume Issue Pages 677-680
Keywords Anisotropic processing; intravascular ultrasound (IVUS); vessel border segmentation; vessel structure classification.
Abstract Restoration of coronary flow after primary percutaneous coronary intervention in acute myocardial infarction does not always correlate with adequate myocardial perfusion. Recently, coronary angiography has been used to assess microcirculation integrity (Myocardial BlushAnalysis, MBA). Although MBA correlates with patient prognosis there are few image processing methods addressing objective perfusion quantification. The goal of this work is to develop statistical descriptors of the myocardial dyeing pattern allowing objective assessment of myocardial perfusion. Experiments on healthy right coronary arteries show that our approach allows reliable measurements without any specific image acquisition protocol.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition (down) Conference
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ GRR2006 Serial 1528
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