Abstract: Writing is one of the most important forms of communication and for centuries, handwriting had been the most reliable way to preserve knowledge. However, despite the recent development of printing houses and electronic devices, handwriting is still broadly used for taking notes, doing annotations, or sketching ideas.
Transferring the ability of understanding handwritten text or recognizing handwritten shapes to computers has been the goal of many researches due to its huge importance for many different fields. However, designing good representations to deal with handwritten shapes, e.g. symbols or words, is a very challenging problem due to the large variability of these kinds of shapes. One of the consequences of working with handwritten shapes is that we need representations to be robust, i.e., able to adapt to large intra-class variability. We need representations to be discriminative, i.e., able to learn what are the differences between classes. And, we need representations to be efficient, i.e., able to be rapidly computed and compared. Unfortunately, current techniques of handwritten shape representation for matching and recognition do not fulfill some or all of these requirements.
Through this thesis we focus on the problem of learning to represent handwritten shapes aimed at retrieval and recognition tasks. Concretely, on the first part of the thesis, we focus on the general problem of representing any kind of handwritten shape. We first present a novel shape descriptor based on a deformable grid that deals with large deformations by adapting to the shape and where the cells of the grid can be used to extract different features. Then, we propose to use this descriptor to learn statistical models, based on the Active Appearance Model, that jointly learns the variability in structure and texture of a given class. Then, on the second part, we focus on a concrete application, the problem of representing handwritten words, for the tasks of word spotting, where the goal is to find all instances of a query word in a dataset of images, and recognition. First, we address the segmentation-free problem and propose an unsupervised, sliding-window-based approach that achieves state-of- the-art results in two public datasets. Second, we address the more challenging multi-writer problem, where the variability in words exponentially increases. We describe an approach in which both word images and text strings are embedded in a common vectorial subspace, and where those that represent the same word are close together. This is achieved by a combination of label embedding and attributes learning, and a common subspace regression. This leads to a low-dimensional, unified representation of word images and strings, resulting in a method that allows one to perform either image and text searches, as well as image transcription, in a unified framework. We evaluate our methods on different public datasets of both handwritten documents and natural images showing results comparable or better than the state-of-the-art on spotting and recognition tasks.

Abstract: Recent advances in endoscopic devices have increased their use for minimal invasive diagnostic and intervention procedures. Among all endoscopic modalities, bronchoscopy is one of the most frequent with around 261 millions of procedures per year. Although the use of bronchoscopy is spread among clinical facilities it presents some drawbacks, being the visual inspection for the assessment of anatomical measurements the most prevalent of them. In
particular, inaccuracies in the estimation of the degree of stenosis (the percentage of obstructed airway) decreases its diagnostic yield and might lead to erroneous treatments. An objective computation of tracheal stenosis in bronchoscopy videos would constitute a breakthrough for this non-invasive technique and a reduction in treatment cost.
This thesis settles the first steps towards on-line reliable extraction of anatomical information from videobronchoscopy for computation of objective measures. In particular, we focus on the computation of the degree of stenosis, which is obtained by comparing the area delimited by a healthy tracheal ring and the stenosed lumen. Reliable extraction of airway structures in interventional videobronchoscopy is a challenging task. This is mainly due to the large variety of acquisition conditions (positions and illumination), devices (different digitalizations) and in videos acquired at the operating room the unpredicted presence of surgical devices (such as probe ends). This thesis contributes to on-line stenosis assessment in several ways. We
propose a parametric strategy for the extraction of lumen and tracheal rings regions based on the characterization of their geometry and appearance that guide a deformable model. The geometric and appearance characterization is based on a physical model describing the way bronchoscopy images are obtained and includes local and global descriptions. In order to ensure a systematic applicability we present a statistical framework to select the optimal
parameters of our method. Experiments perform on the first public annotated database, show that the performance of our method is comparable to the one provided by clinicians and its computation time allows for a on-line implementation in the operating room.

Abstract: Recent advances in thermal infrared imaging (LWIR) has allowed its use in applications beyond of the military domain. Nowadays, this new family of sensors is included in different technical and scientific applications. They offer features that facilitate tasks, such as detection of pedestrians, hot spots, differences in temperature, among others, which can significantly improve the performance of a system where the persons are expected to play the principal role. For instance, video surveillance applications, monitoring, and pedestrian detection.
During this dissertation the next question is stated: Could a couple of sensors measuring different bands of the electromagnetic spectrum, as the visible and thermal infrared, be used to extract depth information? Although it is a complex question, we shows that a system of these characteristics is possible as well as their advantages, drawbacks, and potential opportunities.
The matching and fusion of data coming from different sensors, as the emissions registered at visible and infrared bands, represents a special challenge, because it has been showed that theses signals are weak correlated. Therefore, many traditional techniques of image processing and computer vision are not helpful, requiring adjustments for their correct performance in every modality.
In this research an experimental study that compares different cost functions and matching approaches is performed, in order to build a multimodal stereovision system. Furthermore, the common problems in infrared/visible stereo, specially in the outdoor scenes are identified. Our framework summarizes the architecture of a generic stereo algorithm, at different levels: computational, functional, and structural, which can be extended toward high-level fusion (semantic) and high-order (prior).The proposed framework is intended to explore novel multimodal stereo matching approaches, going from sparse to dense representations (both disparity and depth maps). Moreover, context information is added in form of priors and assumptions. Finally, this dissertation shows a promissory way toward the integration of multiple sensors for recovering three-dimensional information.

Abstract: Colorectal cancer is the third most common cancer worldwide and the second most common malignant tumor in Europe. Screening tests have shown to be very eective in increasing the survival rates since they allow an early detection of polyps. Among the dierent screening techniques, colonoscopy is considered the gold standard although clinical studies mention several problems that have an impact in the quality of the procedure. The navigation through the rectum and colon track can be challenging for the physicians which can increase polyp miss rates. The thorough visualization of the colon track must be ensured so that
the chances of missing lesions are minimized. The visual analysis of colonoscopy images can provide important information to the physicians and support their navigation during the procedure.
Blood vessels and their branching patterns can provide descriptive power to potentially develop biometric markers. Anatomical markers based on blood vessel patterns could be used to identify a particular scene in colonoscopy videos and to support endoscope navigation by generating a sequence of ordered scenes through the dierent colon sections. By verifying the presence of vascular content in the endoluminal scene it is also possible to certify a proper
inspection of the colon mucosa and to improve polyp localization. Considering the potential uses of blood vessel description, this contribution studies the characterization of the vascular content and the analysis of the descriptive power of its branching patterns.
Blood vessel characterization in colonoscopy images is shown to be a challenging task. The endoluminal scene is conformed by several elements whose similar characteristics hinder the development of particular models for each of them. To overcome such diculties we propose the use of the blood vessel branching characteristics as key features for pattern description. We present a model to characterize junctions in binary patterns. The implementation
of the junction model allows us to develop a junction localization method. We
created two data sets including manually labeled vessel information as well as manual ground truths of two types of keypoint landmarks: junctions and endpoints. The proposed method outperforms the available algorithms in the literature in experiments in both, our newly created colon vessel data set, and in DRIVE retinal fundus image data set. In the latter case, we created a manual ground truth of junction coordinates. Since we want to explore the descriptive potential of junctions and vessels, we propose a graph-based approach to
create anatomical markers. In the context of polyp localization, we present a new method to inhibit the in uence of blood vessels in the extraction valley-prole information. The results show that our methodology decreases vessel in
uence, increases polyp information and leads to an improvement in state-of-the-art polyp localization performance. We also propose a polyp-specic segmentation method that outperforms other general and specic approaches.

Abstract: Sketch recognition is a discipline which has gained an increasing interest in the last
20 years. This is due to the appearance of new devices such as PDA, Tablet PC’s
or digital pen & paper protocols. From the wide range of sketched documents we
focus on those that represent structured documents such as: architectural floor-plans,
engineering drawing, UML diagrams, etc. To recognize and understand these kinds
of documents, first we have to recognize the different compounding symbols and then
we have to identify the relations between these elements. From the way that a sketch
is captured, there are two categories: on-line and off-line. On-line input modes refer
to draw directly on a PDA or a Tablet PC’s while off-line input modes refer to scan
a previously drawn sketch.
This thesis is an overlapping of three different areas on Computer Science: Pattern
Recognition, Document Analysis and Human-Computer Interaction. The aim of this
thesis is to interpret sketched documents independently on whether they are captured
on-line or off-line. For this reason, the proposed approach should contain the following
features. First, as we are working with sketches the elements present in our input
contain distortions. Second, as we would work in on-line or off-line input modes, the
order in the input of the primitives is indifferent. Finally, the proposed method should
be applied in real scenarios, its response time must be slow.
To interpret a sketched document we propose a syntactic approach. A syntactic
approach is composed of two correlated components: a grammar and a parser. The
grammar allows describing the different elements on the document as well as their
relations. The parser, given a document checks whether it belongs to the language
generated by the grammar or not. Thus, the grammar should be able to cope with
the distortions appearing on the instances of the elements. Moreover, it would be
necessary to define a symbol independently of the order of their primitives. Concerning to the parser when analyzing 2D sentences, it does not assume an order in the
primitives. Then, at each new primitive in the input, the parser searches among the
previous analyzed symbols candidates to produce a valid reduction.
Taking into account these features, we have proposed a grammar based on Adjacency Grammars. This kind of grammars defines their productions as a multiset
of symbols rather than a list. This allows describing a symbol without an order in
their components. To cope with distortion we have proposed a distortion model.
This distortion model is an attributed estimated over the constraints of the grammar and passed through the productions. This measure gives an idea on how far is the
symbol from its ideal model. In addition to the distortion on the constraints other
distortions appear when working with sketches. These distortions are: overtracing,
overlapping, gaps or spurious strokes. Some grammatical productions have been defined to cope with these errors. Concerning the recognition, we have proposed an
incremental parser with an indexation mechanism. Incremental parsers analyze the
input symbol by symbol given a response to the user when a primitive is analyzed.
This makes incremental parser suitable to work in on-line as well as off-line input
modes. The parser has been adapted with an indexation mechanism based on a spatial division. This indexation mechanism allows setting the primitives in the space
and reducing the search to a neighbourhood.
A third contribution is a grammatical inference algorithm. This method given a
set of symbols captures the production describing it. In the field of formal languages,
different approaches has been proposed but in the graphical domain not so much work
is done in this field. The proposed method is able to capture the production from
a set of symbol although they are drawn in different order. A matching step based
on the Haussdorff distance and the Hungarian method has been proposed to match
the primitives of the different symbols. In addition the proposed approach is able to
capture the variability in the parameters of the constraints.
From the experimental results, we may conclude that we have proposed a robust
approach to describe and recognize sketches. Moreover, the addition of new symbols
to the alphabet is not restricted to an expert. Finally, the proposed approach has
been used in two real scenarios obtaining a good performance.