Abstract: In recent years, deep learning models have considerably advanced the performance of segmentation tasks on Brain Magnetic Resonance Imaging (MRI). However, these models show a considerable performance drop when they are evaluated on unseen data from a different distribution. Since annotation is often a hard and costly task requiring expert supervision, it is necessary to develop ways in which existing models can be adapted to the unseen domains without any additional labelled information. In this work, we explore one such technique which extends the CycleGAN [2] architecture to generate label-preserving data in the target domain. The synthetic target domain data is used to train the nn-UNet [3] framework for the task of multi-label segmentation. The experiments are conducted and evaluated on the dataset [1] provided in the ‘Cross-Modality Domain Adaptation for Medical Image Segmentation’ challenge [23] for segmentation of vestibular schwannoma (VS) tumour and cochlea on contrast enhanced (ceT1) and high resolution (hrT2) MRI scans. In the proposed approach, our model obtains dice scores (DSC) 0.73 and 0.49 for tumour and cochlea respectively on the validation set of the dataset. This indicates the applicability of the proposed technique to real-world problems where data may be obtained by different acquisition protocols as in [1] where hrT2 images are more reliable, safer, and lower-cost alternative to ceT1.

Abstract: Wireless endoscopy is a very recent and at the same time unique technique allowing to visualize and study the occurrence of con- tractions and to analyze the intestine motility. Feature extraction is es- sential for getting efficient patterns to detect contractions in wireless video endoscopy of small intestine. We propose a novel method based on anisotropic image filtering and efficient statistical classification of con- traction features. In particular, we apply the image gradient tensor for mining informative skeletons from the original image and a sequence of descriptors for capturing the characteristic pattern of contractions. Fea- tures extracted from the endoluminal images were evaluated in terms of their discriminatory ability in correct classifying images as either belong- ing to contractions or not. Classification was performed by means of a support vector machine classifier with a radial basis function kernel. Our classification rates gave sensitivity of the order of 90.84% and specificity of the order of 94.43% respectively. These preliminary results highlight the high efficiency of the selected descriptors and support the feasibility of the proposed method in assisting the automatic detection and analysis of contractions.

Abstract: Intravascular Ultrasound (IVUS) is an image-guiding technique for cardiovascular diagnostic, providing cross-sectional images of vessels. During the acquisition, the catheter is pulled back (pullback) at a constant speed in order to acquire spatially subsequent images of the artery. However, during this procedure, the heart twist produces a swinging fluctuation of the probe position along the vessel axis. In this paper we propose a real-time gating algorithm based on the analysis of motion blur variations during the IVUS sequence. Quantitative tests performed on an in-vitro ground truth data base shown that our method is superior to state of the art algorithms both in computational speed and accuracy.

Abstract: The Quantitative Coronary Angiography (QCA) is a methodology used to evaluate the arterial diseases and, in particular, the degree of stenosis. In this paper we propose AQCA, a fully automatic method for vessel segmentation based on graph cut theory. Vesselness, geodesic paths and a new multi-scale edgeness map are used to compute a globally optimal artery segmentation. We evaluate the method performance in a rigorous numerical way on two datasets. The method can detect an artery with precision 92.9 +/- 5% and sensitivity 94.2 +/- 6%. The average absolute distance error between detected and ground truth centerline is 1.13 +/- 0.11 pixels (about 0.27 +/- 0.025 mm) and the absolute relative error in the vessel caliber estimation is 2.93% with almost no bias. Moreover, the method can discriminate between arteries and catheter with an accuracy of 96.4%.

Abstract: We present a method for automatic struts detection and stent shape estimation in cross-sectional intravascular ultrasound images. A stent shape is first estimated through a comprehensive interpretation of the vessel morphology, performed using a supervised context-aware multi-class classification scheme. Then, the successive strut identification exploits both local appearance and the defined stent shape. The method is tested on 589 images obtained from 80 patients, achieving a F-measure of 74.1% and an averaged distance between manual and automatic struts of 0.10 mm.

Abstract: Skin lesion segmentation (SLS) in dermoscopic images is a crucial task for automated diagnosis of melanoma. In this paper, we present a robust deep learning SLS model, so-called SLSDeep, which is represented as an encoder-decoder network. The encoder network is constructed by dilated residual layers, in turn, a pyramid pooling network followed by three convolution layers is used for the decoder. Unlike the traditional methods employing a cross-entropy loss, we investigated a loss function by combining both Negative Log Likelihood (NLL) and End Point Error (EPE) to accurately segment the melanoma regions with sharp boundaries. The robustness of the proposed model was evaluated on two public databases: ISBI 2016 and 2017 for skin lesion analysis towards melanoma detection challenge. The proposed model outperforms the state-of-the-art methods in terms of segmentation accuracy. Moreover, it is capable to segment more than 100 images of size 384x384 per second on a recent GPU.