Frederic Sampedro, Sergio Escalera, Anna Domenech, & Ignasi Carrio. (2014). A computational framework for cancer response assessment based on oncological PET-CT scans. CBM - Computers in Biology and Medicine, 55, 92–99.
Abstract: In this work we present a comprehensive computational framework to help in the clinical assessment of cancer response from a pair of time consecutive oncological PET-CT scans. In this scenario, the design and implementation of a supervised machine learning system to predict and quantify cancer progression or response conditions by introducing a novel feature set that models the underlying clinical context is described. Performance results in 100 clinical cases (corresponding to 200 whole body PET-CT scans) in comparing expert-based visual analysis and classifier decision making show up to 70% accuracy within a completely automatic pipeline and 90% accuracy when providing the system with expert-guided PET tumor segmentation masks.
Keywords: Computer aided diagnosis; Nuclear medicine; Machine learning; Image processing; Quantitative analysis
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Enric Marti, J.Roncaries, Debora Gil, Aura Hernandez-Sabate, Antoni Gurgui, & Ferran Poveda. (2015). PBL On Line: A proposal for the organization, part-time monitoring and assessment of PBL group activities. JOTSE - Journal of Technology and Science Education, 87–96.
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Jorge Bernal, F. Javier Sanchez, Gloria Fernandez Esparrach, Debora Gil, Cristina Rodriguez de Miguel, & Fernando Vilariño. (2015). WM-DOVA Maps for Accurate Polyp Highlighting in Colonoscopy: Validation vs. Saliency Maps from Physicians. CMIG - Computerized Medical Imaging and Graphics, 43, 99–111.
Abstract: We introduce in this paper a novel polyp localization method for colonoscopy videos. Our method is based on a model of appearance for polyps which defines polyp boundaries in terms of valley information. We propose the integration of valley information in a robust way fostering complete, concave and continuous boundaries typically associated to polyps. This integration is done by using a window of radial sectors which accumulate valley information to create WMDOVA1 energy maps related with the likelihood of polyp presence. We perform a double validation of our maps, which include the introduction of two new databases, including the first, up to our knowledge, fully annotated database with clinical metadata associated. First we assess that the highest value corresponds with the location of the polyp in the image. Second, we show that WM-DOVA energy maps can be comparable with saliency maps obtained from physicians' fixations obtained via an eye-tracker. Finally, we prove that our method outperforms state-of-the-art computational saliency results. Our method shows good performance, particularly for small polyps which are reported to be the main sources of polyp miss-rate, which indicates the potential applicability of our method in clinical practice.
Keywords: Polyp localization; Energy Maps; Colonoscopy; Saliency; Valley detection
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Carles Sanchez, Oriol Ramos Terrades, Patricia Marquez, Enric Marti, J.Roncaries, & Debora Gil. (2015). Automatic evaluation of practices in Moodle for Self Learning in Engineering. JOTSE - Journal of Technology and Science Education, 97–106.
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Carles Sanchez, Jorge Bernal, F. Javier Sanchez, Antoni Rosell, Marta Diez-Ferrer, & Debora Gil. (2015). Towards On-line Quantification of Tracheal Stenosis from Videobronchoscopy. IJCAR - International Journal of Computer Assisted Radiology and Surgery, 10(6), 935–945.
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R. Clariso, David Masip, & A. Rius. (2014). Student projects empowering mobile learning in higher education. RUSC - Revista de Universidad y Sociedad del Conocimiento, 192–207.
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Mariella Dimiccoli. (2016). Figure-ground segregation: A fully nonlocal approach. VR - Vision Research, 126, 308–317.
Abstract: We present a computational model that computes and integrates in a nonlocal fashion several configural cues for automatic figure-ground segregation. Our working hypothesis is that the figural status of each pixel is a nonlocal function of several geometric shape properties and it can be estimated without explicitly relying on object boundaries. The methodology is grounded on two elements: multi-directional linear voting and nonlinear diffusion. A first estimation of the figural status of each pixel is obtained as a result of a voting process, in which several differently oriented line-shaped neighborhoods vote to express their belief about the figural status of the pixel. A nonlinear diffusion process is then applied to enforce the coherence of figural status estimates among perceptually homogeneous regions. Computer simulations fit human perception and match the experimental evidence that several cues cooperate in defining figure-ground segregation. The results of this work suggest that figure-ground segregation involves feedback from cells with larger receptive fields in higher visual cortical areas.
Keywords: Figure-ground segregation; Nonlocal approach; Directional linear voting; Nonlinear diffusion
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Jorge Bernal, F. Javier Sanchez, Cristina Rodriguez de Miguel, & Gloria Fernandez Esparrach. (2015). Bulding up the future of colonoscopy: A synergy between clinicians and computer scientists. In Colonoscopy and Colorectal Cancer.
Abstract: Recent advances in endoscopic technology have generated an increasing interest in strengthening the collaboration between clinicians and computers scientist to develop intelligent systems that can provide additional information to clinicians in the different stages of an intervention. The objective of this chapter is to identify clinical drawbacks of colonoscopy in order to define potential areas of collaboration. Once areas are defined, we present the challenges that colonoscopy images present in order computational methods to provide with meaningful output, including those related to image formation and acquisition, as they are proven to have an impact in the performance of an intelligent system. Finally, we also propose how to define validation frameworks in order to assess the performance of a given method, making an special emphasis on how databases should be created and annotated and which metrics should be used to evaluate systems correctly.
Keywords: Intelligent systems; Image properties; Validation; Clinical drawbacks; Endoluminal scene description
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Marco Pedersoli, Andrea Vedaldi, Jordi Gonzalez, & Xavier Roca. (2015). A coarse-to-fine approach for fast deformable object detection. PR - Pattern Recognition, 48(5), 1844–1853.
Abstract: We present a method that can dramatically accelerate object detection with part based models. The method is based on the observation that the cost of detection is likely to be dominated by the cost of matching each part to the image, and not by the cost of computing the optimal configuration of the parts as commonly assumed. Therefore accelerating detection requires minimizing the number of
part-to-image comparisons. To this end we propose a multiple-resolutions hierarchical part based model and a corresponding coarse-to-fine inference procedure that recursively eliminates from the search space unpromising part
placements. The method yields a ten-fold speedup over the standard dynamic programming approach and is complementary to the cascade-of-parts approach of [9]. Compared to the latter, our method does not have parameters to be determined empirically, which simplifies its use during the training of the model. Most importantly, the two techniques can be combined to obtain a very significant speedup, of two orders of magnitude in some cases. We evaluate our method extensively on the PASCAL VOC and INRIA datasets, demonstrating a very high increase in the detection speed with little degradation of the accuracy.
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Jiaolong Xu. (2015). Domain Adaptation of Deformable Part-based Models (Antonio Lopez, Ed.). Ph.D. thesis, , .
Abstract: On-board pedestrian detection is crucial for Advanced Driver Assistance Systems
(ADAS). An accurate classi cation is fundamental for vision-based pedestrian detection.
The underlying assumption for learning classi ers is that the training set and the deployment environment (testing) follow the same probability distribution regarding the features used by the classi ers. However, in practice, there are di erent reasons that can break this constancy assumption. Accordingly, reusing existing classi ers by adapting them from the previous training environment (source domain) to the new testing one (target domain) is an approach with increasing acceptance in the computer vision community. In this thesis we focus on the domain adaptation of deformable part-based models (DPMs) for pedestrian detection. As a prof of concept, we use a computer graphic based synthetic dataset, i.e. a virtual world, as the source domain, and adapt the virtual-world trained DPM detector to various real-world dataset.
We start by exploiting the maximum detection accuracy of the virtual-world
trained DPM. Even though, when operating in various real-world datasets, the virtualworld trained detector still su er from accuracy degradation due to the domain gap of virtual and real worlds. We then focus on domain adaptation of DPM. At the rst step, we consider single source and single target domain adaptation and propose two batch learning methods, namely A-SSVM and SA-SSVM. Later, we further consider leveraging multiple target (sub-)domains for progressive domain adaptation and propose a hierarchical adaptive structured SVM (HA-SSVM) for optimization. Finally, we extend HA-SSVM for the challenging online domain adaptation problem, aiming at making the detector to automatically adapt to the target domain online, without any human intervention. All of the proposed methods in this thesis do not require
revisiting source domain data. The evaluations are done on the Caltech pedestrian detection benchmark. Results show that SA-SSVM slightly outperforms A-SSVM and avoids accuracy drops as high as 15 points when comparing with a non-adapted detector. The hierarchical model learned by HA-SSVM further boosts the domain adaptation performance. Finally, the online domain adaptation method has demonstrated that it can achieve comparable accuracy to the batch learned models while not requiring manually label target domain examples. Domain adaptation for pedestrian detection is of paramount importance and a relatively unexplored area. We humbly hope the work in this thesis could provide foundations for future work in this area.
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Michal Drozdzal, Santiago Segui, Petia Radeva, Carolina Malagelada, Fernando Azpiroz, & Jordi Vitria. (2015). Motility bar: a new tool for motility analysis of endoluminal videos. CBM - Computers in Biology and Medicine, 65, 320–330.
Abstract: Wireless Capsule Endoscopy (WCE) provides a new perspective of the small intestine, since it enables, for the first time, visualization of the entire organ. However, the long visual video analysis time, due to the large number of data in a single WCE study, was an important factor impeding the widespread use of the capsule as a tool for intestinal abnormalities detection. Therefore, the introduction of WCE triggered a new field for the application of computational methods, and in particular, of computer vision. In this paper, we follow the computational approach and come up with a new perspective on the small intestine motility problem. Our approach consists of three steps: first, we review a tool for the visualization of the motility information contained in WCE video; second, we propose algorithms for the characterization of two motility building-blocks: contraction detector and lumen size estimation; finally, we introduce an approach to detect segments of stable motility behavior. Our claims are supported by an evaluation performed with 10 WCE videos, suggesting that our methods ably capture the intestinal motility information.
Keywords: Small intestine; Motility; WCE; Computer vision; Image classification
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Tadashi Araki, Nobutaka Ikeda, Nilanjan Dey, Sayan Chakraborty, Luca Saba, Dinesh Kumar, et al. (2015). A comparative approach of four different image registration techniques for quantitative assessment of coronary artery calcium lesions using intravascular ultrasound. CMPB - Computer Methods and Programs in Biomedicine, 118(2), 158–172.
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Andres Traumann, Gholamreza Anbarjafari, & Sergio Escalera. (2015). Accurate 3D Measurement Using Optical Depth Information. EL - Electronic Letters, 51(18), 1420–1422.
Abstract: A novel three-dimensional measurement technique is proposed. The methodology consists in mapping from the screen coordinates reported by the optical camera to the real world, and integrating distance gradients from the beginning to the end point, while also minimising the error through fitting pixel locations to a smooth curve. The results demonstrate accuracy of less than half a centimetre using Microsoft Kinect II.
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Mohammad Rouhani, & Angel Sappa. (2013). The Richer Representation the Better Registration. TIP - IEEE Transactions on Image Processing, 22(12), 5036–5049.
Abstract: In this paper, the registration problem is formulated as a point to model distance minimization. Unlike most of the existing works, which are based on minimizing a point-wise correspondence term, this formulation avoids the correspondence search that is time-consuming. In the first stage, the target set is described through an implicit function by employing a linear least squares fitting. This function can be either an implicit polynomial or an implicit B-spline from a coarse to fine representation. In the second stage, we show how the obtained implicit representation is used as an interface to convert point-to-point registration into point-to-implicit problem. Furthermore, we show that this registration distance is smooth and can be minimized through the Levengberg-Marquardt algorithm. All the formulations presented for both stages are compact and easy to implement. In addition, we show that our registration method can be handled using any implicit representation though some are coarse and others provide finer representations; hence, a tradeoff between speed and accuracy can be set by employing the right implicit function. Experimental results and comparisons in 2D and 3D show the robustness and the speed of convergence of the proposed approach.
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Carolina Malagelada, Michal Drozdzal, Santiago Segui, Sara Mendez, Jordi Vitria, Petia Radeva, et al. (2015). Classification of functional bowel disorders by objective physiological criteria based on endoluminal image analysis. AJPGI - American Journal of Physiology-Gastrointestinal and Liver Physiology, 309(6), G413–G419.
Abstract: We have previously developed an original method to evaluate small bowel motor function based on computer vision analysis of endoluminal images obtained by capsule endoscopy. Our aim was to demonstrate intestinal motor abnormalities in patients with functional bowel disorders by endoluminal vision analysis. Patients with functional bowel disorders (n = 205) and healthy subjects (n = 136) ingested the endoscopic capsule (Pillcam-SB2, Given-Imaging) after overnight fast and 45 min after gastric exit of the capsule a liquid meal (300 ml, 1 kcal/ml) was administered. Endoluminal image analysis was performed by computer vision and machine learning techniques to define the normal range and to identify clusters of abnormal function. After training the algorithm, we used 196 patients and 48 healthy subjects, completely naive, as test set. In the test set, 51 patients (26%) were detected outside the normal range (P < 0.001 vs. 3 healthy subjects) and clustered into hypo- and hyperdynamic subgroups compared with healthy subjects. Patients with hypodynamic behavior (n = 38) exhibited less luminal closure sequences (41 ± 2% of the recording time vs. 61 ± 2%; P < 0.001) and more static sequences (38 ± 3 vs. 20 ± 2%; P < 0.001); in contrast, patients with hyperdynamic behavior (n = 13) had an increased proportion of luminal closure sequences (73 ± 4 vs. 61 ± 2%; P = 0.029) and more high-motion sequences (3 ± 1 vs. 0.5 ± 0.1%; P < 0.001). Applying an original methodology, we have developed a novel classification of functional gut disorders based on objective, physiological criteria of small bowel function.
Keywords: capsule endoscopy; computer vision analysis; functional bowel disorders; intestinal motility; machine learning
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