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Author Debora Gil; Jaume Garcia; Aura Hernandez-Sabate; Enric Marti
Title Manifold parametrization of the left ventricle for a statistical modelling of its complete anatomy Type Conference Article
Year 2010 Publication 8th Medical Imaging Abbreviated Journal
Volume 7623 Issue 762304 Pages 304
Keywords
Abstract Distortion of Left Ventricle (LV) external anatomy is related to some dysfunctions, such as hypertrophy. The architecture of myocardial fibers determines LV electromechanical activation patterns as well as mechanics. Thus, their joined modelling would allow the design of specific interventions (such as peacemaker implantation and LV remodelling) and therapies (such as resynchronization). On one hand, accurate modelling of external anatomy requires either a dense sampling or a continuous infinite dimensional approach, which requires non-Euclidean statistics. On the other hand, computation of fiber models requires statistics on Riemannian spaces. Most approaches compute separate statistical models for external anatomy and fibers architecture. In this work we propose a general mathematical framework based on differential geometry concepts for computing a statistical model including, both, external and fiber anatomy. Our framework provides a continuous approach to external anatomy supporting standard statistics. We also provide a straightforward formula for the computation of the Riemannian fiber statistics. We have applied our methodology to the computation of complete anatomical atlas of canine hearts from diffusion tensor studies. The orientation of fibers over the average external geometry agrees with the segmental description of orientations reported in the literature.
Address
Corporate Author Thesis
Publisher SPIE Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference SPIE
Notes IAM Approved no
Call Number (up) IAM @ iam @ GGH2010a Serial 1522
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Author Jaume Garcia; Debora Gil; Luis Badiella; Aura Hernandez-Sabate; Francesc Carreras; Sandra Pujades; Enric Marti
Title A Normalized Framework for the Design of Feature Spaces Assessing the Left Ventricular Function Type Journal Article
Year 2010 Publication IEEE Transactions on Medical Imaging Abbreviated Journal TMI
Volume 29 Issue 3 Pages 733-745
Keywords
Abstract A through description of the left ventricle functionality requires combining complementary regional scores. A main limitation is the lack of multiparametric normality models oriented to the assessment of regional wall motion abnormalities (RWMA). This paper covers two main topics involved in RWMA assessment. We propose a general framework allowing the fusion and comparison across subjects of different regional scores. Our framework is used to explore which combination of regional scores (including 2-D motion and strains) is better suited for RWMA detection. Our statistical analysis indicates that for a proper (within interobserver variability) identification of RWMA, models should consider motion and extreme strains.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0278-0062 ISBN Medium
Area Expedition Conference
Notes IAM Approved no
Call Number (up) IAM @ iam @ GGH2010b Serial 1507
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Author Jaume Garcia; Debora Gil; Aura Hernandez-Sabate
Title Endowing Canonical Geometries to Cardiac Structures Type Book Chapter
Year 2010 Publication Statistical Atlases And Computational Models Of The Heart Abbreviated Journal
Volume 6364 Issue Pages 124-133
Keywords
Abstract International conference on Cardiac electrophysiological simulation challenge
In this paper, we show that canonical (shape-based) geometries can be endowed to cardiac structures using tubular coordinates defined over their medial axis. We give an analytic formulation of these geometries by means of B-Splines. Since B-Splines present vector space structure PCA can be applied to their control points and statistical models relating boundaries and the interior of the anatomical structures can be derived. We demonstrate the applicability in two cardiac structures, the 3D Left Ventricular volume, and the 2D Left-Right ventricle set in 2D Short Axis view.
Address
Corporate Author Thesis
Publisher Springer Berlin / Heidelberg Place of Publication Editor Camara, O.; Pop, M.; Rhode, K.; Sermesant, M.; Smith, N.; Young, A.
Language Summary Language Original Title
Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM Approved no
Call Number (up) IAM @ iam @ GGH2010b Serial 1515
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Author Sandra Pujades;Francesc Carreras;Manuel Ballester; Jaume Garcia; Debora Gil
Title A Normalized Parametric Domain for the Analysis of the Left Ventricular Function Type Conference Article
Year 2008 Publication Proceedings of the Third International Conference on Computer Vision Theory and Applications (VISAPP’08) Abbreviated Journal
Volume 1 Issue Pages 267-274
Keywords Helical Ventricular Myocardial Band; Myocardial Fiber; Tagged Magnetic Resonance; HARP; Optical Flow Variational Framework; Gabor Filters; B-Splines.
Abstract Impairment of left ventricular (LV) contractility due to cardiovascular diseases is reflected in LV motion patterns. The mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fiber. The helical ventricular myocardial band (HVMB) concept describes the myocardial muscle as a unique muscular band that twists in space in a non homogeneous fashion. The 3D anisotropy of the ventricular band fibers suggests a regional analysis of the heart motion. Computation of normality models of such motion can help in the detection and localization of any cardiac disorder. In this paper we introduce, for the first time, a normalized parametric domain that allows comparison of the left ventricle motion across patients. We address, both, extraction of the LV motion from Tagged Magnetic Resonance images, as well as, defining a mapping of the LV to a common normalized domain. Extraction of normality motion patterns from 17 healthy volunteers shows the clinical potential of our LV parametrization.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM; Approved no
Call Number (up) IAM @ iam @ GGP2008 Serial 1627
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Author Debora Gil; Jordi Gonzalez; Gemma Sanchez (eds)
Title Computer Vision: Advances in Research and Development Type Book Whole
Year 2007 Publication Proceedings of the 2nd CVC International Workshop Abbreviated Journal
Volume Issue Pages
Keywords
Abstract
Address
Corporate Author Thesis
Publisher UAB Place of Publication Bellaterra (Spain) Editor Debora Gil; Jordi Gonzalez; Gemma Sanchez
Language Summary Language Original Title
Series Editor Series Title 2 Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN 978-84-935251-4-9 Medium
Area Expedition Conference
Notes IAM; ISE; DAG Approved no
Call Number (up) IAM @ iam @ GGS2007 Serial 1493
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Author Debora Gil; Jaume Garcia; Mariano Vazquez; Ruth Aris; Guilleaume Houzeaux
Title Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function Type Conference Article
Year 2008 Publication 8th World Congress on Computational Mechanichs (WCCM8) Abbreviated Journal
Volume Issue Pages
Keywords Left Ventricle, Electromechanical Models, Image Processing, Magnetic Resonance.
Abstract Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models [1] consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality [2]. In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp [3].
We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment.
The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted.
The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have
Figure 1: Scheme for the Left Ventricle Patient-Sensitive Model.
computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model.
Address Venice; Italy
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN 9788496736559 Medium
Area Expedition Conference
Notes IAM; Approved no
Call Number (up) IAM @ iam @ GGV2008b Serial 993
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Author Debora Gil; Jaume Garcia; Manuel Vazquez; Ruth Aris; Guillaume Houzeaux
Title Patient-Sensitive Anatomic and Functional 3D Model of the Left Ventricle Function Type Conference Article
Year 2008 Publication 8th World Congress on Computational Mechanichs (WCCM8)/5th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2008) Abbreviated Journal
Volume Issue Pages
Keywords Left Ventricle; Electromechanical Models; Image Processing; Magnetic Resonance.
Abstract Early diagnosis and accurate treatment of Left Ventricle (LV) dysfunction significantly increases the patient survival. Impairment of LV contractility due to cardiovascular diseases is reflected in its motion patterns. Recent advances in medical imaging, such as Magnetic Resonance (MR), have encouraged research on 3D simulation and modelling of the LV dynamics. Most of the existing 3D models consider just the gross anatomy of the LV and restore a truncated ellipse which deforms along the cardiac cycle. The contraction mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fibers. It follows that such simplified models do not allow evaluation of the heart electro-mechanical function and coupling, which has recently risen as the key point for understanding the LV functionality . In order to thoroughly understand the LV mechanics it is necessary to consider the complete anatomy of the LV given by the orientation of the myocardial fibres in 3D space as described by Torrent Guasp. We propose developing a 3D patient-sensitive model of the LV integrating, for the first time, the ven- tricular band anatomy (fibers orientation), the LV gross anatomy and its functionality. Such model will represent the LV function as a natural consequence of its own ventricular band anatomy. This might be decisive in restoring a proper LV contraction in patients undergoing pace marker treatment. The LV function is defined as soon as the propagation of the contractile electromechanical pulse has been modelled. In our experiments we have used the wave equation for the propagation of the electric pulse. The electromechanical wave moves on the myocardial surface and should have a conductivity tensor oriented along the muscular fibers. Thus, whatever mathematical model for electric pulse propa- gation [4] we consider, the complete anatomy of the LV should be extracted. The LV gross anatomy is obtained by processing multi slice MR images recorded for each patient. Information about the myocardial fibers distribution can only be extracted by Diffusion Tensor Imag- ing (DTI), which can not provide in vivo information for each patient. As a first approach, we have computed an average model of fibers from several DTI studies of canine hearts. This rough anatomy is the input for our electro-mechanical propagation model simulating LV dynamics. The average fiber orientation is updated until the simulated LV motion agrees with the experimental evidence provided by the LV motion observed in tagged MR (TMR) sequences. Experimental LV motion is recovered by applying image processing, differential geometry and interpolation techniques to 2D TMR slices [5]. The pipeline in figure 1 outlines the interaction between simulations and experimental data leading to our patient-tailored model.
Address
Corporate Author Thesis
Publisher Place of Publication Venezia (Italia) Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN B-31470-08 ISBN Medium
Area Expedition Conference
Notes IAM Approved no
Call Number (up) IAM @ iam @ GGV2008c Serial 1521
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Author Debora Gil; Aura Hernandez-Sabate; Mireia Burnat; Steven Jansen; Jordi Martinez-Vilalta
Title Structure-Preserving Smoothing of Biomedical Images Type Conference Article
Year 2009 Publication 13th International Conference on Computer Analysis of Images and Patterns Abbreviated Journal
Volume 5702 Issue Pages 427-434
Keywords non-linear smoothing; differential geometry; anatomical structures segmentation; cardiac magnetic resonance; computerized tomography.
Abstract Smoothing of biomedical images should preserve gray-level transitions between adjacent tissues, while restoring contours consistent with anatomical structures. Anisotropic diffusion operators are based on image appearance discontinuities (either local or contextual) and might fail at weak inter-tissue transitions. Meanwhile, the output of block-wise and morphological operations is prone to present a block structure due to the shape and size of the considered pixel neighborhood. In this contribution, we use differential geometry concepts to define a diffusion operator that restricts to image consistent level-sets. In this manner, the final state is a non-uniform intensity image presenting homogeneous inter-tissue transitions along anatomical structures, while smoothing intra-structure texture. Experiments on different types of medical images (magnetic resonance, computerized tomography) illustrate its benefit on a further process (such as segmentation) of images.
Address Münster, Germany
Corporate Author Thesis
Publisher Springer Berlin Heidelberg Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title LNCS
Series Volume Series Issue Edition
ISSN 0302-9743 ISBN 978-3-642-03766-5 Medium
Area Expedition Conference CAIP
Notes IAM Approved no
Call Number (up) IAM @ iam @ GHB2009 Serial 1527
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Author Debora Gil; Aura Hernandez-Sabate; Mireia Brunat;Steven Jansen; Jordi Martinez-Vilalta
Title Structure-preserving smoothing of biomedical images Type Journal Article
Year 2011 Publication Pattern Recognition Abbreviated Journal PR
Volume 44 Issue 9 Pages 1842-1851
Keywords Non-linear smoothing; Differential geometry; Anatomical structures; segmentation; Cardiac magnetic resonance; Computerized tomography
Abstract Smoothing of biomedical images should preserve gray-level transitions between adjacent tissues, while restoring contours consistent with anatomical structures. Anisotropic diffusion operators are based on image appearance discontinuities (either local or contextual) and might fail at weak inter-tissue transitions. Meanwhile, the output of block-wise and morphological operations is prone to present a block structure due to the shape and size of the considered pixel neighborhood. In this contribution, we use differential geometry concepts to define a diffusion operator that restricts to image consistent level-sets. In this manner, the final state is a non-uniform intensity image presenting homogeneous inter-tissue transitions along anatomical structures, while smoothing intra-structure texture. Experiments on different types of medical images (magnetic resonance, computerized tomography) illustrate its benefit on a further process (such as segmentation) of images.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-3203 ISBN Medium
Area Expedition Conference
Notes IAM; ADAS Approved no
Call Number (up) IAM @ iam @ GHB2011 Serial 1526
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Author Debora Gil; Aura Hernandez-Sabate; Oriol Rodriguez; J. Mauri; Petia Radeva
Title Statistical Strategy for Anisotropic Adventitia Modelling in IVUS Type Journal Article
Year 2006 Publication IEEE Transactions on Medical Imaging Abbreviated Journal
Volume 25 Issue 6 Pages 768-778
Keywords Corners; T-junctions; Wavelets
Abstract Vessel plaque assessment by analysis of intravascular ultrasound sequences is a useful tool for cardiac disease diagnosis and intervention. Manual detection of luminal (inner) and mediaadventitia (external) vessel borders is the main activity of physicians in the process of lumen narrowing (plaque) quantification. Difficult definition of vessel border descriptors, as well as, shades, artifacts, and blurred signal response due to ultrasound physical properties trouble automated adventitia segmentation. In order to efficiently approach such a complex problem, we propose blending advanced anisotropic filtering operators and statistical classification techniques into a vessel border modelling strategy. Our systematic statistical analysis shows that the reported adventitia detection achieves an accuracy in the range of interobserver variability regardless of plaque nature, vessel geometry, and incomplete vessel borders. Index Terms–-Anisotropic processing, intravascular ultrasound (IVUS), vessel border segmentation, vessel structure classification.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number (up) IAM @ iam @ GHR2006 Serial 1525
Permanent link to this record
 

 
Author Debora Gil
Title Regularized Curvature Flow Type Report
Year 2002 Publication CVC Technical Report Abbreviated Journal
Volume Issue 63 Pages
Keywords
Abstract
Address
Corporate Author Thesis
Publisher Computer Vision Centre Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM; Approved no
Call Number (up) IAM @ iam @ Gil2002 Serial 1518
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Author Debora Gil
Title Geometric Differential Operators for Shape Modelling Type Book Whole
Year 2004 Publication PhD Thesis, Universitat Autonoma de Barcelona-CVC Abbreviated Journal
Volume Issue Pages
Keywords
Abstract Medical imaging feeds research in many computer vision and image processing fields: image filtering, segmentation, shape recovery, registration, retrieval and pattern matching. Because of their low contrast changes and large variety of artifacts and noise, medical imaging processing techniques relying on an analysis of the geometry of image level sets rather than on intensity values result in more robust treatment. From the starting point of treatment of intravascular images, this PhD thesis ad- dresses the design of differential image operators based on geometric principles for a robust shape modelling and restoration. Among all fields applying shape recovery, we approach filtering and segmentation of image objects. For a successful use in real images, the segmentation process should go through three stages: noise removing, shape modelling and shape recovery. This PhD addresses all three topics, but for the sake of algorithms as automated as possible, techniques for image processing will be designed to satisfy three main principles: a) convergence of the iterative schemes to non-trivial states avoiding image degeneration to a constant image and representing smooth models of the originals; b) smooth asymptotic behav- ior ensuring stabilization of the iterative process; c) fixed parameter values ensuring equal (domain free) performance of the algorithms whatever initial images/shapes. Our geometric approach to the generic equations that model the different processes approached enables defining techniques satisfying all the former requirements. First, we introduce a new curvature-based geometric flow for image filtering achieving a good compromise between noise removing and resemblance to original images. Sec- ond, we describe a new family of diffusion operators that restrict their scope to image level curves and serve to restore smooth closed models from unconnected sets of points. Finally, we design a regularization of snake (distance) maps that ensures its smooth convergence towards any closed shape. Experiments show that performance of the techniques proposed overpasses that of state-of-the-art algorithms.
Address
Corporate Author Thesis Ph.D. thesis
Publisher Ediciones Graficas Rey Place of Publication Barcelona (Spain) Editor Jordi Saludes i Closa;Petia Radeva
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN 84-933652-0-3 Medium prit
Area Expedition Conference
Notes IAM; Approved no
Call Number (up) IAM @ iam @ GIL2004 Serial 1517
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Author Debora Gil; Petia Radeva
Title Curvature based Distance Maps Type Report
Year 2003 Publication CVC Technical Report Abbreviated Journal
Volume Issue 70 Pages
Keywords
Abstract
Address
Corporate Author Thesis
Publisher Computer Vision Center Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number (up) IAM @ iam @ GIR2003a Serial 1534
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Author Debora Gil; Petia Radeva
Title Curvature Vector Flow to Assure Convergent Deformable Models for Shape Modelling Type Book Chapter
Year 2003 Publication Energy Minimization Methods In Computer Vision And Pattern Recognition Abbreviated Journal LNCS
Volume 2683 Issue Pages 357-372
Keywords Initial condition; Convex shape; Non convex analysis; Increase; Segmentation; Gradient; Standard; Standards; Concave shape; Flow models; Tracking; Edge detection; Curvature
Abstract Poor convergence to concave shapes is a main limitation of snakes as a standard segmentation and shape modelling technique. The gradient of the external energy of the snake represents a force that pushes the snake into concave regions, as its internal energy increases when new inexion points are created. In spite of the improvement of the external energy by the gradient vector ow technique, highly non convex shapes can not be obtained, yet. In the present paper, we develop a new external energy based on the geometry of the curve to be modelled. By tracking back the deformation of a curve that evolves by minimum curvature ow, we construct a distance map that encapsulates the natural way of adapting to non convex shapes. The gradient of this map, which we call curvature vector ow (CVF), is capable of attracting a snake towards any contour, whatever its geometry. Our experiments show that, any initial snake condition converges to the curve to be modelled in optimal time.
Address
Corporate Author Thesis
Publisher Springer, Berlin Place of Publication Lisbon, PORTUGAL Editor Springer, B.
Language Summary Language Original Title
Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS
Series Volume Series Issue Edition
ISSN 0302-9743 ISBN 3-540-40498-8 Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number (up) IAM @ iam @ GIR2003b Serial 1535
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Author Debora Gil; Petia Radeva
Title Inhibition of False Landmarks Type Book Chapter
Year 2004 Publication Recent Advances in Artificial Intelligence Research and Development Abbreviated Journal
Volume Issue Pages 233-244
Keywords
Abstract We argue that a corner detector should be based on the degree of continuity of the tangent vector to the image level sets, work on the image domain and need no assumptions on neither the image local structure nor the particular geometry of the corner/junction. An operator measuring the degree of differentiability of the projection matrix on the image gradient fulfills the above requirements. Its high sensitivity to changes in vector directions makes it suitable for landmark location in real images prone to need smoothing to reduce the impact of noise. Because using smoothing kernels leads to corner misplacement, we suggest an alternative fake response remover based on the receptive field inhibition of spurious details. The combination of both orientation discontinuity detection and noise inhibition produce our Inhibition Orientation Energy (IOE) landmark locator.
Address
Corporate Author Thesis
Publisher IOS Press Place of Publication Barcelona (Spain) Editor al, J.V. et
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number (up) IAM @ iam @ GiR2004a Serial 1533
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