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| Author | David Roche; Debora Gil; Jesus Giraldo | ||||
| Title | Assessing agonist efficacy in an uncertain Em world | Type | Conference Article | ||
| Year | 2012 | Publication | 40th Keystone Symposia on mollecular and celular biology | Abbreviated Journal | |
| Volume | Issue | Pages | 79 | ||
| Keywords | |||||
| Abstract | The operational model of agonism has been widely used for the analysis of agonist action since its formulation in 1983. The model includes the Em parameter, which is defined as the maximum response of the system. The methods for Em estimation provide Em values not significantly higher than the maximum responses achieved by full agonists. However, it has been found that that some classes of compounds as, for instance, superagonists and positive allosteric modulators can increase the full agonist maximum response, implying upper limits for Em and thereby posing doubts on the validity of Em estimates. Because of the correlation between Em and operational efficacy, τ, wrong Em estimates will yield wrong τ estimates.
In this presentation, the operational model of agonism and various methods for the simulation of allosteric modulation will be analyzed. Alternatives for curve fitting will be presented and discussed. |
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| Address | Fairmont Banff Springs, Banff, Alberta, Canada | ||||
| Corporate Author | Keystone Symposia | Thesis | |||
| Publisher | Keystone Symposia | Place of Publication | Editor | A. Christopoulus and M. Bouvier | |
| Language | english | Summary Language | english | Original Title | |
| Series Editor | Keystone Symposia | Series Title | Abbreviated Series Title | ||
| Series Volume | Series Issue | Edition | |||
| ISSN | ISBN | Medium | |||
| Area | Expedition | Conference | KSMCB | ||
| Notes | IAM | Approved | no | ||
Call Number  |
IAM @ iam @ RGG2012 | Serial | 1855 | ||
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| Author | Carles Sanchez;F. Javier Sanchez; Antoni Rosell; Debora Gil | ||||
| Title | An illumination model of the trachea appearance in videobronchoscopy images | Type | Book Chapter | ||
| Year | 2012 | Publication | Image Analysis and Recognition | Abbreviated Journal | LNCS |
| Volume | 7325 | Issue | Pages | 313-320 | |
| Keywords | Bronchoscopy, tracheal ring, stenosis assesment, trachea appearance model, segmentation | ||||
| Abstract | Videobronchoscopy is a medical imaging technique that allows interactive navigation inside the respiratory pathways. This imaging modality provides realistic images and allows non-invasive minimal intervention procedures. Tracheal procedures are routinary interventions that require assessment of the percentage of obstructed pathway for injury (stenosis) detection. Visual assessment in videobronchoscopic sequences requires high expertise of trachea anatomy and is prone to human error.
This paper introduces an automatic method for the estimation of steneosed trachea percentage reduction in videobronchoscopic images. We look for tracheal rings , whose deformation determines the degree of obstruction. For ring extraction , we present a ring detector based on an illumination and appearance model. This model allows us to parametrise the ring detection. Finally, we can infer optimal estimation parameters for any video resolution. |
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| Address | Aveiro, Portugal | ||||
| Corporate Author | Thesis | ||||
| Publisher | Springer Berlin Heidelberg | Place of Publication | Editor | ||
| Language | Summary Language | Original Title | |||
| Series Editor | Series Title | Lecture Notes in Computer Science | Abbreviated Series Title | LNCS | |
| Series Volume | Series Issue | Edition | |||
| ISSN | 0302-9743 | ISBN | 978-3-642-31297-7 | Medium | |
| Area | 800 | Expedition | Conference | ICIAR | |
| Notes | MV;IAM | Approved | no | ||
| Call Number |
IAM @ iam @ SSR2012 | Serial | 1898 | ||
| Permanent link to this record | |||||
| Author | Sergio Vera; Debora Gil; Agnes Borras; F. Javier Sanchez; Frederic Perez; Marius G. Linguraru; Miguel Angel Gonzalez Ballester | ||||
| Title | Computation and Evaluation of Medial Surfaces for Shape Representation of Abdominal Organs | Type | Book Chapter | ||
| Year | 2012 | Publication | Workshop on Computational and Clinical Applications in Abdominal Imaging | Abbreviated Journal | |
| Volume | 7029 | Issue | Pages | 223–230 | |
| Keywords | medial manifolds, abdomen. | ||||
| Abstract | Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Existing methods show excellent results when applied to 2D
objects, but their quality drops across dimensions. This paper contributes to the computation of medial manifolds in two aspects. First, we provide a standard scheme for the computation of medial manifolds that avoid degenerated medial axis segments; second, we introduce an energy based method which performs independently of the dimension. We evaluate quantitatively the performance of our method with respect to existing approaches, by applying them to synthetic shapes of known medial geometry. Finally, we show results on shape representation of multiple abdominal organs, exploring the use of medial manifolds for the representation of multi-organ relations. |
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| Address | Toronto; Canada; | ||||
| Corporate Author | Thesis | ||||
| Publisher | Springer Link | Place of Publication | Berlin | Editor | H. Yoshida et al |
| Language | English | Summary Language | English | Original Title | |
| Series Editor | Series Title | Lecture Notes in Computer Science | Abbreviated Series Title | LNCS | |
| Series Volume | Series Issue | Edition | |||
| ISSN | 0302-9743 | ISBN | 978-3-642-28556-1 | Medium | |
| Area | Expedition | Conference | ABDI | ||
| Notes | IAM;MV | Approved | no | ||
| Call Number |
IAM @ iam @ VGB2012 | Serial | 1834 | ||
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| Author | Sergio Vera; Miguel Angel Gonzalez Ballester; Debora Gil | ||||
| Title | A medial map capturing the essential geometry of organs | Type | Conference Article | ||
| Year | 2012 | Publication | ISBI Workshop on Open Source Medical Image Analysis software | Abbreviated Journal | |
| Volume | Issue | Pages | 1691 - 1694 | ||
| Keywords | Medial Surface Representation, Volume Reconstruction,Geometry , Image reconstruction , Liver , Manifolds , Shape , Surface morphology , Surface reconstruction | ||||
| Abstract | Medial representations are powerful tools for describing and parameterizing the volumetric shape of anatomical structures. Accurate computation of one pixel wide medial surfaces is mandatory. Those surfaces must represent faithfully the geometry of the volume. Although morphological methods produce excellent results in 2D, their complexity and quality drops across dimensions, due to a more complex description of pixel neighborhoods. This paper introduces a continuous operator for accurate and efficient computation of medial structures of arbitrary dimension. Our experiments show its higher performance for medical imaging applications in terms of simplicity of medial structures and capability for reconstructing the anatomical volume | ||||
| Address | Barcelona,Spain | ||||
| Corporate Author | Thesis | ||||
| Publisher | IEEE | Place of Publication | Editor | ||
| Language | Summary Language | Original Title | |||
| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | 1945-7928 | ISBN | 978-1-4577-1857-1 | Medium | |
| Area | Expedition | Conference | ISBI | ||
| Notes | IAM | Approved | no | ||
| Call Number |
IAM @ iam @ VGG2012a | Serial | 1989 | ||
| Permanent link to this record | |||||
| Author | Sergio Vera; Miguel Angel Gonzalez Ballester; Debora Gil | ||||
| Title | Optimal Medial Surface Generation for Anatomical Volume Representations | Type | Book Chapter | ||
| Year | 2012 | Publication | Abdominal Imaging. Computational and Clinical Applications | Abbreviated Journal | LNCS |
| Volume | 7601 | Issue | Pages | 265-273 | |
| Keywords | Medial surface representation; volume reconstruction | ||||
| Abstract | Medial representations are a widely used technique in abdominal organ shape representation and parametrization. Those methods require good medial manifolds as a starting point. Any medial
surface used to parametrize a volume should be simple enough to allow an easy manipulation and complete enough to allow an accurate reconstruction of the volume. Obtaining good quality medial surfaces is still a problem with current iterative thinning methods. This forces the usage of generic, pre-calculated medial templates that are adapted to the final shape at the cost of a drop in volume reconstruction. This paper describes an operator for generation of medial structures that generates clean and complete manifolds well suited for their further use in medial representations of abdominal organ volumes. While being simpler than thinning surfaces, experiments show its high performance in volume reconstruction and preservation of medial surface main branching topology. |
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| Address | Nice, France | ||||
| Corporate Author | Thesis | ||||
| Publisher | Springer Berlin Heidelberg | Place of Publication | Editor | Yoshida, Hiroyuki and Hawkes, David and Vannier, MichaelW. | |
| Language | Summary Language | Original Title | |||
| Series Editor | Series Title | Lecture Notes in Computer Science | Abbreviated Series Title | ||
| Series Volume | Series Issue | Edition | |||
| ISSN | 0302-9743 | ISBN | 978-3-642-33611-9 | Medium | |
| Area | Expedition | Conference | STACOM | ||
| Notes | IAM | Approved | no | ||
| Call Number |
IAM @ iam @ VGG2012b | Serial | 1988 | ||
| Permanent link to this record | |||||
| Author | Sergio Vera; Debora Gil; Antonio Lopez; Miguel Angel Gonzalez Ballester | ||||
| Title | Multilocal Creaseness Measure | Type | Journal | ||
| Year | 2012 | Publication | The Insight Journal | Abbreviated Journal | IJ |
| Volume | Issue | Pages | |||
| Keywords | Ridges, Valley, Creaseness, Structure Tensor, Skeleton, | ||||
| Abstract | This document describes the implementation using the Insight Toolkit of an algorithm for detecting creases (ridges and valleys) in N-dimensional images, based on the Local Structure Tensor of the image. In addition to the filter used to calculate the creaseness image, a filter for the computation of the structure tensor is also included in this submission. | ||||
| Address | |||||
| Corporate Author | Alma IT Systems | Thesis | |||
| Publisher | Place of Publication | Editor | |||
| Language | english | Summary Language | english | Original Title | |
| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | ISBN | Medium | |||
| Area | Expedition | Conference | |||
| Notes | IAM;ADAS; | Approved | no | ||
| Call Number |
IAM @ iam @ VGL2012 | Serial | 1840 | ||
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| Author | Jordi Roca; Maria Vanrell; C. Alejandro Parraga | ||||
| Title | What is constant in colour constancy? | Type | Conference Article | ||
| Year | 2012 | Publication | 6th European Conference on Colour in Graphics, Imaging and Vision | Abbreviated Journal | |
| Volume | Issue | Pages | 337-343 | ||
| Keywords | |||||
| Abstract | Color constancy refers to the ability of the human visual system to stabilize
the color appearance of surfaces under an illuminant change. In this work we studied how the interrelations among nine colors are perceived under illuminant changes, particularly whether they remain stable across 10 different conditions (5 illuminants and 2 backgrounds). To do so we have used a paradigm that measures several colors under an immersive state of adaptation. From our measures we defined a perceptual structure descriptor that is up to 87% stable over all conditions, suggesting that color category features could be used to predict color constancy. This is in agreement with previous results on the stability of border categories [1,2] and with computational color constancy algorithms [3] for estimating the scene illuminant. |
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| Corporate Author | Thesis | ||||
| Publisher | Place of Publication | Editor | |||
| Language | Summary Language | Original Title | |||
| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | ISBN | 9781622767014 | Medium | ||
| Area | Expedition | Conference | CGIV | ||
| Notes | CIC | Approved | no | ||
| Call Number |
RVP2012 | Serial | 2189 | ||
| Permanent link to this record | |||||