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Author (up) Debora Gil; Oriol Ramos Terrades; Raquel Perez
Title Topological Radiomics (TOPiomics): Early Detection of Genetic Abnormalities in Cancer Treatment Evolution Type Book Chapter
Year 2021 Publication Extended Abstracts GEOMVAP 2019, Trends in Mathematics 15 Abbreviated Journal
Volume 15 Issue Pages 89–93
Keywords
Abstract Abnormalities in radiomic measures correlate to genomic alterations prone to alter the outcome of personalized anti-cancer treatments. TOPiomics is a new method for the early detection of variations in tumor imaging phenotype from a topological structure in multi-view radiomic spaces.
Address
Corporate Author Thesis
Publisher Springer Nature Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM; DAG; 600.120; 600.145; 600.139 Approved no
Call Number Admin @ si @ GRP2021 Serial 3594
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Author (up) Debora Gil; Oriol Rodriguez-Leon; Petia Radeva; Josepa Mauri
Title Myocardial Perfusion Characterization From Contrast Angiography Spectral Distribution Type Journal Article
Year 2008 Publication IEEE Transactions on Medical Imaging Abbreviated Journal
Volume 27 Issue 5 Pages 641-649
Keywords Contrast angiography; myocardial perfusion; spectral analysis.
Abstract Despite recovering a normal coronary flow after acute myocardial infarction, percutaneous coronary intervention does not guarantee a proper perfusion (irrigation) of the infarcted area. This damage in microcirculation integrity may detrimentally affect the patient survival. Visual assessment of the myocardium opacification in contrast angiography serves to define a subjective score of the microcirculation integrity myocardial blush analysis (MBA). Although MBA correlates with patient prognosis its visual assessment is a very difficult task that requires of a highly expertise training in order to achieve a good intraobserver and interobserver agreement. In this paper, we provide objective descriptors of the myocardium staining pattern by analyzing the spectrum of the image local statistics. The descriptors proposed discriminate among the different phenomena observed in the angiographic sequence and allow defining an objective score of the myocardial perfusion.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ GRR2008 Serial 1541
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Author (up) Debora Gil; Oriol Rodriguez; Josepa Mauri; Petia Radeva
Title Statistical descriptors of the Myocardial perfusion in angiographic images Type Conference Article
Year 2006 Publication Proc. Computers in Cardiology Abbreviated Journal
Volume Issue Pages 677-680
Keywords Anisotropic processing; intravascular ultrasound (IVUS); vessel border segmentation; vessel structure classification.
Abstract Restoration of coronary flow after primary percutaneous coronary intervention in acute myocardial infarction does not always correlate with adequate myocardial perfusion. Recently, coronary angiography has been used to assess microcirculation integrity (Myocardial BlushAnalysis, MBA). Although MBA correlates with patient prognosis there are few image processing methods addressing objective perfusion quantification. The goal of this work is to develop statistical descriptors of the myocardial dyeing pattern allowing objective assessment of myocardial perfusion. Experiments on healthy right coronary arteries show that our approach allows reliable measurements without any specific image acquisition protocol.
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Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ GRR2006 Serial 1528
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Author (up) Debora Gil; Petia Radeva
Title A Regularized Curvature Flow Designed for a Selective Shape Restoration Type Journal Article
Year 2004 Publication IEEE Transactions on Image Processing Abbreviated Journal
Volume 13 Issue Pages 1444–1458
Keywords Geometric flows, nonlinear filtering, shape recovery.
Abstract Among all filtering techniques, those based exclu- sively on image level sets (geometric flows) have proven to be the less sensitive to the nature of noise and the most contrast preserving. A common feature to existent curvature flows is that they penalize high curvature, regardless of the curve regularity. This constitutes a major drawback since curvature extreme values are standard descriptors of the contour geometry. We argue that an operator designed with shape recovery purposes should include a term penalizing irregularity in the curvature rather than its magnitude. To this purpose, we present a novel geometric flow that includes a function that measures the degree of local irregularity present in the curve. A main advantage is that it achieves non-trivial steady states representing a smooth model of level curves in a noisy image. Performance of our approach is compared to classical filtering techniques in terms of quality in the restored image/shape and asymptotic behavior. We empirically prove that our approach is the technique that achieves the best compromise between image quality and evolution stabilization.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number BCNPCL @ bcnpcl @ GiR2004b Serial 491
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Author (up) Debora Gil; Petia Radeva
Title Inhibition of false landmarks Type Journal Article
Year 2006 Publication Pattern Recognition Letters Abbreviated Journal PRL
Volume 27 Issue 9 Pages 1022-1030
Keywords
Abstract Corners and junctions are landmarks characterized by the lack of differentiability in the unit tangent to the image level curve. Detectors based on differential operators are not, by their own definition, the best posed as they require a higher degree of differentiability to yield a reliable response. We argue that a corner detector should be based on the degree of continuity of the tangent vector to the image level sets, work on the image domain and need no assumptions on neither the image local structure nor the particular geometry of the corner/junction. An operator measuring the degree of differentiability of the projection matrix on the image gradient fulfills the above requirements. Because using smoothing kernels leads to corner misplacement, we suggest an alternative fake response remover based on the receptive field inhibition of spurious details. The combination of both orientation discontinuity detection and noise inhibition produce our inhibition orientation energy (IOE) landmark locator.
Address
Corporate Author Thesis
Publisher Elsevier Science Inc. Place of Publication New York, NY, USA Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0167-8655 ISBN Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ GiR2006 Serial 1529
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Author (up) Debora Gil; Petia Radeva
Title Extending anisotropic operators to recover smooth shapes Type Journal Article
Year 2005 Publication Computer Vision and Image Understanding Abbreviated Journal
Volume 99 Issue 1 Pages 110-125
Keywords Contour completion; Functional extension; Differential operators; Riemmanian manifolds; Snake segmentation
Abstract Anisotropic differential operators are widely used in image enhancement processes. Recently, their property of smoothly extending functions to the whole image domain has begun to be exploited. Strong ellipticity of differential operators is a requirement that ensures existence of a unique solution. This condition is too restrictive for operators designed to extend image level sets: their own functionality implies that they should restrict to some vector field. The diffusion tensor that defines the diffusion operator links anisotropic processes with Riemmanian manifolds. In this context, degeneracy implies restricting diffusion to the varieties generated by the vector fields of positive eigenvalues, provided that an integrability condition is satisfied. We will use that any smooth vector field fulfills this integrability requirement to design line connection algorithms for contour completion. As application we present a segmenting strategy that assures convergent snakes whatever the geometry of the object to be modelled is.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1077-3142 ISBN Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ GIR2005 Serial 1530
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Author (up) Debora Gil; Petia Radeva
Title Shape Restoration via a Regularized Curvature Flow Type Journal Article
Year 2004 Publication Journal of Mathematical Imaging and Vision Abbreviated Journal
Volume 21 Issue 3 Pages 205-223
Keywords
Abstract Any image filtering operator designed for automatic shape restoration should satisfy robustness (whatever the nature and degree of noise is) as well as non-trivial smooth asymptotic behavior. Moreover, a stopping criterion should be determined by characteristics of the evolved image rather than dependent on the number of iterations. Among the several PDE based techniques, curvature flows appear to be highly reliable for strongly noisy images compared to image diffusion processes.
In the present paper, we introduce a regularized curvature flow (RCF) that admits non-trivial steady states. It is based on a measure of the local curve smoothness that takes into account regularity of the curve curvature and serves as stopping term in the mean curvature flow. We prove that this measure decreases over the orbits of RCF, which endows the method with a natural stop criterion in terms of the magnitude of this measure. Further, in its discrete version it produces steady states consisting of piece-wise regular curves. Numerical experiments made on synthetic shapes corrupted with different kinds of noise show the abilities and limitations of each of the current geometric flows and the benefits of RCF. Finally, we present results on real images that illustrate the usefulness of the present approach in practical applications.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ GiR2004c Serial 1532
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Author (up) Debora Gil; Petia Radeva
Title Inhibition of False Landmarks Type Book Chapter
Year 2004 Publication Recent Advances in Artificial Intelligence Research and Development Abbreviated Journal
Volume Issue Pages 233-244
Keywords
Abstract We argue that a corner detector should be based on the degree of continuity of the tangent vector to the image level sets, work on the image domain and need no assumptions on neither the image local structure nor the particular geometry of the corner/junction. An operator measuring the degree of differentiability of the projection matrix on the image gradient fulfills the above requirements. Its high sensitivity to changes in vector directions makes it suitable for landmark location in real images prone to need smoothing to reduce the impact of noise. Because using smoothing kernels leads to corner misplacement, we suggest an alternative fake response remover based on the receptive field inhibition of spurious details. The combination of both orientation discontinuity detection and noise inhibition produce our Inhibition Orientation Energy (IOE) landmark locator.
Address
Corporate Author Thesis
Publisher IOS Press Place of Publication Barcelona (Spain) Editor al, J.V. et
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ GiR2004a Serial 1533
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Author (up) Debora Gil; Petia Radeva
Title Curvature based Distance Maps Type Report
Year 2003 Publication CVC Technical Report Abbreviated Journal
Volume Issue 70 Pages
Keywords
Abstract
Address
Corporate Author Thesis
Publisher Computer Vision Center Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ GIR2003a Serial 1534
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Author (up) Debora Gil; Petia Radeva
Title Curvature Vector Flow to Assure Convergent Deformable Models for Shape Modelling Type Book Chapter
Year 2003 Publication Energy Minimization Methods In Computer Vision And Pattern Recognition Abbreviated Journal LNCS
Volume 2683 Issue Pages 357-372
Keywords Initial condition; Convex shape; Non convex analysis; Increase; Segmentation; Gradient; Standard; Standards; Concave shape; Flow models; Tracking; Edge detection; Curvature
Abstract Poor convergence to concave shapes is a main limitation of snakes as a standard segmentation and shape modelling technique. The gradient of the external energy of the snake represents a force that pushes the snake into concave regions, as its internal energy increases when new inexion points are created. In spite of the improvement of the external energy by the gradient vector ow technique, highly non convex shapes can not be obtained, yet. In the present paper, we develop a new external energy based on the geometry of the curve to be modelled. By tracking back the deformation of a curve that evolves by minimum curvature ow, we construct a distance map that encapsulates the natural way of adapting to non convex shapes. The gradient of this map, which we call curvature vector ow (CVF), is capable of attracting a snake towards any contour, whatever its geometry. Our experiments show that, any initial snake condition converges to the curve to be modelled in optimal time.
Address
Corporate Author Thesis
Publisher Springer, Berlin Place of Publication Lisbon, PORTUGAL Editor Springer, B.
Language Summary Language Original Title
Series Editor Series Title Lecture Notes in Computer Science Abbreviated Series Title LNCS
Series Volume Series Issue Edition
ISSN 0302-9743 ISBN 3-540-40498-8 Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ GIR2003b Serial 1535
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Author (up) Debora Gil; Petia Radeva; Fernando Vilariño
Title Anisotropic Contour Completion Type Conference Article
Year 2003 Publication Proceedings of the IEEE International Conference on Image Processing Abbreviated Journal
Volume Issue Pages
Keywords
Abstract In this paper we introduce a novel application of the diffusion tensor for anisotropic image processing. The Anisotropic Contour Completion (ACC) we suggest consists in extending the characteristic function of the open curve by means of a degenerated diffusion tensor that prevents any diffusion in the normal direction. We show that ACC is equivalent to a dilation with a continuous elliptic structural element that takes into account the local orientation of the contours to be closed. Experiments on contours extracted from real images show that ACC produces shapes able to adapt to any curve in an active contour framework. 1.
Address
Corporate Author Thesis
Publisher Place of Publication Barcelona, Spain Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN 0-7803-7751-6 Medium
Area Expedition Conference
Notes IAM;MV;MILAB;SIAI Approved no
Call Number IAM @ iam @ GRV2003 Serial 1539
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Author (up) Debora Gil; Petia Radeva; Jordi Saludes; Josefina Mauri
Title Automatic Segmentation of Artery Wall in Coronary IVUS Images: A Probabilistic Approach Type Conference Article
Year 2000 Publication International Conference on Pattern Recognition Abbreviated Journal
Volume 4 Issue Pages 352-355
Keywords
Abstract Intravascular ultrasound images represent a unique tool to analyze the morphology of arteries and vessels (plaques, restenosis, etc). The poor quality of these images makes unsupervised segmentation based on traditional segmentation algorithms (such as edge or ridge/valley detection) fail to achieve the expected results. In this paper we present a probabilistic flexible template to separate different regions in the image. In particular, we use elliptic templates to model and detect the shape of the vessel inner wall in IVUS images. We present the results of successful segmentation obtained from patients undergoing stent treatment. A physician team has validated these results.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ GRS2000a Serial 1537
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Author (up) Debora Gil; Petia Radeva; Jordi Saludes; Josefina Mauri
Title Automatic Segmentation of Artery Wall in Coronary IVUS Images: a Probabilistic Approach Type Conference Article
Year 2000 Publication Proceedings of CIC’2000 Abbreviated Journal
Volume Issue Pages
Keywords
Abstract Intravascular ultrasound images represent a unique tool to analyze the morphology of arteries and vessels (plaques, restenosis, etc). The poor quality of these images makes unsupervised segmentation based on traditional segmentation algorithms (such as edge or ridge/valley detection) fail to achieve the expected results. In this paper we present a probabilistic flexible template to separate different regions in the image. In particular, we use elliptic templates to model and detect the shape of the vessel inner wall in IVUS images. We present the results of successful segmentation obtained from patients undergoing stent treatment. A physician team has validated these results.
Address
Corporate Author Thesis
Publisher Place of Publication Cambridge, Massachussets Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference CIC
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ GRS2000 Serial 1538
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Author (up) Debora Gil; Petia Radeva; Josefina Mauri
Title Ivus Segmentation Via a Regularized Curvature Flow Type Conference Article
Year 2002 Publication X Congreso Anual de la Sociedad Española de Ingeniería Biomédica CASEIB 2002 Abbreviated Journal
Volume Issue Pages 133-136
Keywords
Abstract Cardiac diseases are diagnosed and treated through a study of the morphology and dynamics of cardiac arteries. In- travascular Ultrasound (IVUS) imaging is of high interest to physicians since it provides both information. At the current state-of-the-art in image segmentation, a robust detection of the arterial lumen in IVUS demands manual intervention or ECG-gating. Manual intervention is a tedious and time consuming task that requires experienced observers, meanwhile ECG-gating is an acquisition technique not available in all clinical centers. We introduce a parametric algorithm that detects the arterial luminal border in in vivo sequences. The method consist in smoothing the sequences’ level surfaces under a regularized mean curvature flow that admits non-trivial steady states. The flow is based on a measure of the surface local smoothness that takes into account regularity of the surface curvature.
Address
Corporate Author Thesis
Publisher Place of Publication Saragossa, Espanya Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM;MILAB Approved no
Call Number IAM @ iam @ GRM2002 Serial 1536
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Author (up) Debora Gil; Rosa Maria Ortiz; Carles Sanchez; Antoni Rosell
Title Objective endoscopic measurements of central airway stenosis. A pilot study Type Journal Article
Year 2018 Publication Respiration Abbreviated Journal RES
Volume 95 Issue Pages 63–69
Keywords Bronchoscopy; Tracheal stenosis; Airway stenosis; Computer-assisted analysis
Abstract Endoscopic estimation of the degree of stenosis in central airway obstruction is subjective and highly variable. Objective: To determine the benefits of using SENSA (System for Endoscopic Stenosis Assessment), an image-based computational software, for obtaining objective stenosis index (SI) measurements among a group of expert bronchoscopists and general pulmonologists. Methods: A total of 7 expert bronchoscopists and 7 general pulmonologists were enrolled to validate SENSA usage. The SI obtained by the physicians and by SENSA were compared with a reference SI to set their precision in SI computation. We used SENSA to efficiently obtain this reference SI in 11 selected cases of benign stenosis. A Web platform with three user-friendly microtasks was designed to gather the data. The users had to visually estimate the SI from videos with and without contours of the normal and the obstructed area provided by SENSA. The users were able to modify the SENSA contours to define the reference SI using morphometric bronchoscopy. Results: Visual SI estimation accuracy was associated with neither bronchoscopic experience (p = 0.71) nor the contours of the normal and the obstructed area provided by the system (p = 0.13). The precision of the SI by SENSA was 97.7% (95% CI: 92.4-103.7), which is significantly better than the precision of the SI by visual estimation (p < 0.001), with an improvement by at least 15%. Conclusion: SENSA provides objective SI measurements with a precision of up to 99.5%, which can be calculated from any bronchoscope using an affordable scalable interface. Providing normal and obstructed contours on bronchoscopic videos does not improve physicians' visual estimation of the SI.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes IAM; 600.075; 600.096; 600.145 Approved no
Call Number Admin @ si @ GOS2018 Serial 3043
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