Abstract: Intravascular Ultrasound (IVUS) data validation is usually performed by comparing post-mortem (in-vitro) IVUS data and corresponding histological analysis of the tissue, obtaining a reliable ground truth. The main drawback of this method is the few number of available study cases due to the complex procedure of histological analysis. In this work we propose a novel semi-supervised approach to enhance the in-vitro training set by including examples from in-vivo coronary plaques data set. For this purpose, a Sequential Floating Forward Selection method is applied on in-vivo data and plaque characterization performances are evaluated by Leave-One-Patient-Out cross-validation technique. Supervised data inclusion improves global classification accuracy from 89.39% to 91.82%.

Abstract: Segmentation in the surveillance domain has to deal with shadows to avoid distortions when detecting moving objects. Most segmentation approaches dealing with shadow detection are typically restricted to penumbra shadows. Therefore, such techniques cannot cope well with umbra shadows. Consequently, umbra shadows are usually detected as part of moving objects. In this paper we present a novel technique based on gradient and colour models for separating chromatic moving cast shadows from detected moving objects. Firstly, both a chromatic invariant colour cone model and an invariant gradient model are built to perform automatic segmentation while detecting potential shadows. In a second step, regions corresponding to potential shadows are grouped by considering “a bluish effect” and an edge partitioning. Lastly, (i) temporal similarities between textures and (ii) spatial similarities between chrominance angle and brightness distortions are analysed for all potential shadow regions in order to finally identify umbra shadows. Unlike other approaches, our method does not make any a-priori assumptions about camera location, surface geometries, surface textures, shapes and types of shadows, objects, and background. Experimental results show the performance and accuracy of our approach in different shadowed materials and illumination conditions.

Abstract: Cardiovascular Diseases, specially those affecting the Left Ventricle (LV), are the leading cause of death in developed countries with approximately a 30% of all global deaths. In order to address this public health concern, physicians focus on diagnosis and therapy planning. On one hand, early and accurate detection of Regional Wall Motion Abnormalities (RWMA) significantly contributes to a quick diagnosis and prevents the patient to reach more severe stages. On the other hand, a thouroughly knowledge of the normal gross anatomy of the LV, as well as, the distribution of its muscular fibers is crucial for designing specific interventions and therapies (such as pacemaker implanction). Statistical models obtained from the analysis of different imaging modalities allow the computation of the normal ranges of variation within a given population. Normality models are a valuable tool for the definition of objective criterions quantifying the degree of (anomalous) deviation of the LV function and anatomy for a given subject. The creation of statistical models involve addressing three main issues: extraction of data from images, definition of a common domain for comparison of data across patients and designing appropriate statistical analysis schemes. In this PhD thesis we present generic image processing tools for the creation of statistical models of the LV anatomy and function. On one hand, we use differential geometry concepts to define a computational framework (the Normalized Parametric Domain, NPD) suitable for the comparison and fusion of several clinical scores obtained over the LV. On the other hand, we present a variational approach (the Harmonic Phase Flow, HPF) for the estimation of myocardial motion that provides dense and continuous vector fields without overestimating motion at injured areas. These tools are used for the creation of statistical models. Regarding anatomy, we obtain an atlas jointly modelling, both, LV gross anatomy and fiber architecture. Regarding function, we compute normality patterns of scores characterizing the (global and local) LV function and explore, for the first time, the configuration of local scores better suited for RWMA detection.

Abstract: The estimation of the illuminant of a scene from a digital image has been the goal of a large amount of research in computer vision. Color constancy algorithms have dealt with this problem by defining different heuristics to select a unique solution from within the feasible set. The performance of these algorithms has shown that there is still a long way to go to globally solve this problem as a preliminary step in computer vision. In general, performance evaluation has been done by comparing the angular error between the estimated chromaticity and the chromaticity of a canonical illuminant, which is highly dependent on the image dataset. Recently, some workers have used high-level constraints to estimate illuminants; in this case selection is based on increasing the performance on the subsequent steps of the systems. In this paper we propose a new performance measure, the perceptual angular error. It evaluates the performance of a color constancy algorithm according to the perceptual preferences of humans, or naturalness (instead of the actual optimal solution) and is independent of the visual task. We show the results of a new psychophysical experiment comparing solutions from three different color constancy algorithms. Our results show that in more than a half of the judgments the preferred solution is not the one closest to the optimal solution. Our experiments were performed on a new dataset of images acquired with a calibrated camera with an attached neutral grey sphere, which better copes with the illuminant variations of the scene.