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Author  |
Sergio Vera |
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Title |
Anatomic Registration based on Medial Axis Parametrizations |
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Book Whole |
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Year |
2015 |
Publication |
PhD Thesis, Universitat Autonoma de Barcelona-CVC |
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Abstract |
Image registration has been for many years the gold standard method to bring two images into correspondence. It has been used extensively in the eld of medical imaging in order to put images of di erent patients into a common overlapping spatial position. However, medical image registration is a slow, iterative optimization process, where many variables and prone to fall into the pit traps local minima.
A coordinate system parameterizing the interior of organs is a powerful tool for a systematic localization of injured tissue. If the same coordinate values are assigned to speci c anatomical sites, parameterizations ensure integration of data across different medical image modalities. Harmonic mappings have been used to produce parametric meshes over the surface of anatomical shapes, given their ability to set values at speci c locations through boundary conditions. However, most of the existing implementations in medical imaging restrict to either anatomical surfaces, or the depth coordinate with boundary conditions is given at discrete sites of limited geometric diversity.
The medial surface of the shape can be used to provide a continuous basis for the de nition of a depth coordinate. However, given that di erent methods for generation of medial surfaces generate di erent manifolds, not all of them are equally suited to be the basis of radial coordinate for a parameterization. It would be desirable that the medial surface will be smooth, and robust to surface shape noise, with low number of spurious branches or surfaces.
In this thesis we present methods for computation of smooth medial manifolds and apply them to the generation of for anatomical volumetric parameterization that extends current harmonic parameterizations to the interior anatomy using information provided by the volume medial surface. This reference system sets a solid base for creating anatomical models of the anatomical shapes, and allows comparing several patients in a common framework of reference. |
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November 2015 |
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Thesis |
Ph.D. thesis |
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Publisher |
Ediciones Graficas Rey |
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Editor |
Debora Gil;Miguel Angel Gonzalez Ballester |
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978-84-943427-8-3 |
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Notes |
IAM; 600.075 |
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Call Number |
Admin @ si @ Ver2015 |
Serial |
2708 |
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Author |
Sergio Vera |
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Title |
Finger joint modelling from hand X-ray images for assessing rheumatoid arthritis |
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Report |
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Year |
2010 |
Publication |
CVC Technical Report |
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164 |
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Keywords |
Rheumatoid arthritis; joint detection; X-ray; Van der Heijde score |
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Abstract |
Rheumatoid arthritis is an autoimmune, systemic, inflammatory disorder that mainly af- fects bone joints. While there is no cure for this disease, continuous advances on palliative treatments require frequent verification of patient’s illness evolution. Such evolution is mea- sured through several available semi-quantitative methods that require evaluation of hand and foot X-ray images. Accurate assessment is a time consuming task that requires highly trained personnel. This hinders a generalized use in clinical practice for early diagnose and disease follow-up. In the context of the automatization of such evaluation methods we present a method for detection and characterization of finger joints in hand radiography images. Several measures for assessing the reduction of joint space width are proposed. We compare for the first time such measures to the Van der Heijde score, the gold standard method for rheumatoid arthritis assessment. The proposed method outperforms existing strategies with a detection rate above 95%. Our comparison to Van der Heijde index shows a promising correlation that encourages further research. |
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Master's thesis |
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Bellaterra 01893, Barcelona, Spain |
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IAM |
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Call Number |
IAM @ iam @ Ver2010 |
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1661 |
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