Abstract: Impairment of left ventricular (LV) contractility due to cardiovascular diseases is reflected in LV motion patterns. The mechanics of any muscle strongly depends on the spatial orientation of its muscular fibers since the motion that the muscle undergoes mainly takes place along the fiber. The helical ventricular myocardial band (HVMB) concept describes the myocardial muscle as a unique muscular band that twists in space in a non homogeneous fashion. The 3D anisotropy of the ventricular band fibers suggests a regional analysis of the heart motion. Computation of normality models of such motion can help in the detection and localization of any cardiac disorder. In this paper we introduce, for the first time, a normalized parametric domain that allows comparison of the left ventricle motion across patients. We address, both, extraction of the LV motion from Tagged Magnetic Resonance images, as well as, defining a mapping of the LV to a common normalized domain. Extraction of normality motion patterns from 17 healthy volunteers shows the clinical potential of our LV parametrization.

Abstract: Many real problems require multi-class decisions. In the Pattern Recognition field,
many techniques have been proposed to deal with the binary problem. However,
the extension of many 2-class classifiers to the multi-class case is a hard task. In
this sense, Error-Correcting Output Codes (ECOC) demonstrated to be a powerful
tool to combine any number of binary classifiers to model multi-class problems. But
there are still many open issues about the capabilities of the ECOC framework. In
this thesis, the two main stages of an ECOC design are analyzed: the coding and
the decoding steps. We present different problem-dependent designs. These designs
take advantage of the knowledge of the problem domain to minimize the number
of classifiers, obtaining a high classification performance. On the other hand, we
analyze the ECOC codification in order to define new decoding rules that take full
benefit from the information provided at the coding step. Moreover, as a successful
classification requires a rich feature set, new feature detection/extraction techniques
are presented and evaluated on the new ECOC designs. The evaluation of the new
methodology is performed on different real and synthetic data sets: UCI Machine
Learning Repository, handwriting symbols, traffic signs from a Mobile Mapping System, Intravascular Ultrasound images, Caltech Repository data set or Chaga’s disease
data set. The results of this thesis show that significant performance improvements
are obtained on both traditional coding and decoding ECOC designs when the new
coding and decoding rules are taken into account.