Abstract: Background: COVID-19 infection, especially in cases with pneumonia, is associated with a high rate of pulmonary embolism (PE). In patients with contraindications for CT pulmonary angiography (CTPA) or non-diagnostic CTPA, perfusion single-photon emission computed tomography/computed tomography (Q-SPECT/CT) is a diagnostic alternative. The goal of this study is to develop a radiomic diagnostic system to detect PE based only on the analysis of Q-SPECT/CT scans.
Methods: This radiomic diagnostic system is based on a local analysis of Q-SPECT/CT volumes that includes both CT and Q-SPECT values for each volume point. We present a combined approach that uses radiomic features extracted from each scan as input into a fully connected classifcation neural network that optimizes a weighted crossentropy loss trained to discriminate between three diferent types of image patterns (pixel sample level): healthy lungs (control group), PE and pneumonia. Four types of models using diferent confguration of parameters were tested.
Results: The proposed radiomic diagnostic system was trained on 20 patients (4,927 sets of samples of three types of image patterns) and validated in a group of 39 patients (4,410 sets of samples of three types of image patterns). In the training group, COVID-19 infection corresponded to 45% of the cases and 51.28% in the test group. In the test group, the best model for determining diferent types of image patterns with PE presented a sensitivity, specifcity, positive predictive value and negative predictive value of 75.1%, 98.2%, 88.9% and 95.4%, respectively. The best model for detecting
pneumonia presented a sensitivity, specifcity, positive predictive value and negative predictive value of 94.1%, 93.6%, 85.2% and 97.6%, respectively. The area under the curve (AUC) was 0.92 for PE and 0.91 for pneumonia. When the results obtained at the pixel sample level are aggregated into regions of interest, the sensitivity of the PE increases to 85%, and all metrics improve for pneumonia.
Conclusion: This radiomic diagnostic system was able to identify the diferent lung imaging patterns and is a frst step toward a comprehensive intelligent radiomic system to optimize the diagnosis of PE by Q-SPECT/CT.

Abstract: A novel three-dimensional measurement technique is proposed. The methodology consists in mapping from the screen coordinates reported by the optical camera to the real world, and integrating distance gradients from the beginning to the end point, while also minimising the error through fitting pixel locations to a smooth curve. The results demonstrate accuracy of less than half a centimetre using Microsoft Kinect II.

Abstract: Motion perception is an amazing innate ability of the creatures on the planet. This adroitness entails a functional advantage that enables species to compete better in the wild. The motion perception ability is usually employed at different levels, allowing from the simplest interaction with the ’physis’ up to the most transcendental survival tasks. Among the five classical perception system , vision is the most widely used in the motion perception field. Millions years of evolution have led to a highly specialized visual system in humans, which is characterized by a tremendous accuracy as well as an extraordinary robustness. Although humans and an immense diversity of species can distinguish moving object with a seeming simplicity, it has proven to be a difficult and non trivial problem from a computational perspective. In the field of Computer Vision, the detection of moving objects is a challenging and fundamental research area. This can be referred to as the ’origin’ of vast and numerous vision-based research sub-areas. Nevertheless, from the bottom to the top of this hierarchical analysis, the foundations still relies on when and where motion has occurred in an image. Pixels corresponding to moving objects in image sequences can be identified by measuring changes in their values. However, a pixel’s value (representing a combination of color and brightness) could also vary due to other factors such as: variation in scene illumination, camera noise and nonlinear sensor responses among others. The challenge lies in detecting if the changes in pixels’ value are caused by a genuine object movement or not. An additional challenging aspect in motion detection is represented by moving cast shadows. The paradox arises because a moving object and its cast shadow share similar motion patterns. However, a moving cast shadow is not a moving object. In fact, a shadow represents a photometric illumination effect caused by the relative position of the object with respect to the light sources. Shadow detection methods are mainly divided in two domains depending on the application field. One normally consists of static images where shadows are casted by static objects, whereas the second one is referred to image sequences where shadows are casted by moving objects. For the first case, shadows can provide additional geometric and semantic cues about shape and position of its casting object as well as the localization of the light source. Although the previous information can be extracted from static images as well as video sequences, the main focus in the second area is usually change detection, scene matching or surveillance. In this context, a shadow can severely affect with the analysis and interpretation of the scene. The work done in the thesis is focused on the second case, thus it addresses the problem of detection and removal of moving cast shadows in video sequences in order to enhance the detection of moving object.

Abstract: Micro-expressions reveal underlying emotions and are widely applied in political psychology, lie detection, law enforcement and medical care. Micro-expression spotting aims to detect the temporal locations of facial expressions from video sequences and is a crucial task in micro-expression recognition. In this study, the problem of micro-expression spotting is formulated as micro-expression classification per frame. We propose an effective spotting model with sliding windows called the spatio-temporal spotting network. The method involves a sliding window detection mechanism, combines the spatial features from the local key frames and the global temporal features and performs micro-expression spotting. The experiments are conducted on the CAS(ME)2 database and the SAMM Long Videos database, and the results demonstrate that the proposed method outperforms the state-of-the-art method by 30.58% for the CAS(ME)2 and 23.98% for the SAMM Long Videos according to overall F-scores.

Abstract: Background and study aims: To evaluate a new computational histology prediction system based on colorectal polyp textural surface patterns using high definition white light images.
Patients and methods: Textural elements (textons) were characterized according to their contrast with respect to the surface, shape and number of bifurcations, assuming that dysplastic polyps are associated with highly contrasted, large tubular patterns with some degree of bifurcation. Computer-aided diagnosis (CAD) was compared with pathological diagnosis and the diagnosis by the endoscopists using Kudo and NICE classification.
Results: Images of 225 polyps were evaluated (142 dysplastic and 83 non-dysplastic). CAD system correctly classified 205 (91.1%) polyps, 131/142 (92.3%) dysplastic and 74/83 (89.2%) non-dysplastic. For the subgroup of 100 diminutive (<5 mm) polyps, CAD correctly classified 87 (87%) polyps, 43/50 (86%) dysplastic and 44/50 (88%) non-dysplastic. There were not statistically significant differences in polyp histology prediction based on CAD system and on endoscopist assessment.
Conclusion: A computer vision system based on the characterization of the polyp surface in the white light accurately predicts colorectal polyp histology.

Abstract: BACKGROUND : Artificial intelligence (AI) research in colonoscopy is progressing rapidly but widespread clinical implementation is not yet a reality. We aimed to identify the top implementation research priorities. METHODS : An established modified Delphi approach for research priority setting was used. Fifteen international experts, including endoscopists and translational computer scientists/engineers, from nine countries participated in an online survey over 9 months. Questions related to AI implementation in colonoscopy were generated as a long-list in the first round, and then scored in two subsequent rounds to identify the top 10 research questions. RESULTS : The top 10 ranked questions were categorized into five themes. Theme 1: clinical trial design/end points (4 questions), related to optimum trial designs for polyp detection and characterization, determining the optimal end points for evaluation of AI, and demonstrating impact on interval cancer rates. Theme 2: technological developments (3 questions), including improving detection of more challenging and advanced lesions, reduction of false-positive rates, and minimizing latency. Theme 3: clinical adoption/integration (1 question), concerning the effective combination of detection and characterization into one workflow. Theme 4: data access/annotation (1 question), concerning more efficient or automated data annotation methods to reduce the burden on human experts. Theme 5: regulatory approval (1 question), related to making regulatory approval processes more efficient. CONCLUSIONS : This is the first reported international research priority setting exercise for AI in colonoscopy. The study findings should be used as a framework to guide future research with key stakeholders to accelerate the clinical implementation of AI in endoscopy.

Abstract: In this paper, a deep learning approach, Restricted Boltzmann Machine (RBM), is used to perform automatic hand sign language recognition from visual data. We evaluate how RBM, as a deep generative model, is capable of generating the distribution of the input data for an enhanced recognition of unseen data. Two modalities, RGB and Depth, are considered in the model input in three forms: original image, cropped image, and noisy cropped image. Five crops of the input image are used and the hand of these cropped images are detected using Convolutional Neural Network (CNN). After that, three types of the detected hand images are generated for each modality and input to RBMs. The outputs of the RBMs for two modalities are fused in another RBM in order to recognize the output sign label of the input image. The proposed multi-modal model is trained on all and part of the American alphabet and digits of four publicly available datasets. We also evaluate the robustness of the proposal against noise. Experimental results show that the proposed multi-modal model, using crops and the RBM fusing methodology, achieves state-of-the-art results on Massey University Gesture Dataset 2012, American Sign Language (ASL). and Fingerspelling Dataset from the University of Surrey’s Center for Vision, Speech and Signal Processing, NYU, and ASL Fingerspelling A datasets.

Abstract: Action recognition is a challenging task that plays an important role in many robotic systems, which highly depend on visual input feeds. However, due to privacy concerns, it is important to find a method which can recognise actions without using visual feed. In this paper, we propose a concept for detecting actions while preserving the test subject’s privacy. Our proposed method relies only on recording the temporal evolution of light pulses scattered back from the scene.
Such data trace to record one action contains a sequence of one-dimensional arrays of voltage values acquired by a single-pixel detector at 1 GHz repetition rate. Information about both the distance to the object and its shape are embedded in the traces. We apply machine learning in the form of recurrent neural networks for data analysis and demonstrate successful action recognition. The experimental results show that our proposed method could achieve on average 96.47% accuracy on the actions walking forward, walking backwards, sitting down, standing up and waving hand, using recurrent
neural network.