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Fosca De Iorio, Carolina Malagelada, Fernando Azpiroz, M. Maluenda, C. Violanti, Laura Igual, et al. (2009). Intestinal motor activity, endoluminal motion and transit. NEUMOT - Neurogastroenterology & Motility, 21(12), 1264–e119.
Abstract: A programme for evaluation of intestinal motility has been recently developed based on endoluminal image analysis using computer vision methodology and machine learning techniques. Our aim was to determine the effect of intestinal muscle inhibition on wall motion, dynamics of luminal content and transit in the small bowel. Fourteen healthy subjects ingested the endoscopic capsule (Pillcam, Given Imaging) in fasting conditions. Seven of them received glucagon (4.8 microg kg(-1) bolus followed by a 9.6 microg kg(-1) h(-1) infusion during 1 h) and in the other seven, fasting activity was recorded, as controls. This dose of glucagon has previously shown to inhibit both tonic and phasic intestinal motor activity. Endoluminal image and displacement was analyzed by means of a computer vision programme specifically developed for the evaluation of muscular activity (contractile and non-contractile patterns), intestinal contents, endoluminal motion and transit. Thirty-minute periods before, during and after glucagon infusion were analyzed and compared with equivalent periods in controls. No differences were found in the parameters measured during the baseline (pretest) periods when comparing glucagon and control experiments. During glucagon infusion, there was a significant reduction in contractile activity (0.2 +/- 0.1 vs 4.2 +/- 0.9 luminal closures per min, P < 0.05; 0.4 +/- 0.1 vs 3.4 +/- 1.2% of images with radial wrinkles, P < 0.05) and a significant reduction of endoluminal motion (82 +/- 9 vs 21 +/- 10% of static images, P < 0.05). Endoluminal image analysis, by means of computer vision and machine learning techniques, can reliably detect reduced intestinal muscle activity and motion.
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Oriol Pujol, & David Masip. (2009). Geometry-Based Ensembles: Toward a Structural Characterization of the Classification Boundary. TPAMI - IEEE Transactions on Pattern Analysis and Machine Intelligence, 31(6), 1140–1146.
Abstract: This article introduces a novel binary discriminative learning technique based on the approximation of the non-linear decision boundary by a piece-wise linear smooth additive model. The decision border is geometrically defined by means of the characterizing boundary points – points that belong to the optimal boundary under a certain notion of robustness. Based on these points, a set of locally robust linear classifiers is defined and assembled by means of a Tikhonov regularized optimization procedure in an additive model to create a final lambda-smooth decision rule. As a result, a very simple and robust classifier with a strong geometrical meaning and non-linear behavior is obtained. The simplicity of the method allows its extension to cope with some of nowadays machine learning challenges, such as online learning, large scale learning or parallelization, with linear computational complexity. We validate our approach on the UCI database. Finally, we apply our technique in online and large scale scenarios, and in six real life computer vision and pattern recognition problems: gender recognition, intravascular ultrasound tissue classification, speed traffic sign detection, Chagas' disease severity detection, clef classification and action recognition using a 3D accelerometer data. The results are promising and this paper opens a line of research that deserves further attention
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Fernando Vilariño, Stephan Ameling, Gerard Lacey, Stephen Patchett, & Hugh Mulcahy. (2009). Eye Tracking Search Patterns in Expert and Trainee Colonoscopists: A Novel Method of Assessing Endoscopic Competency? GI - Gastrointestinal Endoscopy, 69(5), 370.
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David Masip, & Jordi Vitria. (2008). Shared Feature Extraction for Nearest Neighbor Face Recognition. IEEE Transactions on Neural Networks, 586–595.
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Bogdan Raducanu, & Jordi Vitria. (2008). Learning to Learn: From Smarts Machines to Intelligent Machines. PRL - Patter Recognition Letters, 1024–1032.
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