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Fernando Vilariño, Ludmila I. Kuncheva, & Petia Radeva. (2006). ROC curves and video analysis optimization in intestinal capsule endoscopy. PRL - Pattern Recognition Letters, 27(8), 875–881.
Abstract: Wireless capsule endoscopy involves inspection of hours of video material by a highly qualified professional. Time episodes corresponding to intestinal contractions, which are of interest to the physician constitute about 1% of the video. The problem is to label automatically time episodes containing contractions so that only a fraction of the video needs inspection. As the classes of contraction and non-contraction images in the video are largely imbalanced, ROC curves are used to optimize the trade-off between false positive and false negative rates. Classifier ensemble methods and simple classifiers were examined. Our results reinforce the claims from recent literature that classifier ensemble methods specifically designed for imbalanced problems have substantial advantages over simple classifiers and standard classifier ensembles. By using ROC curves with the bagging ensemble method the inspection time can be drastically reduced at the expense of a small fraction of missed contractions.
Keywords: ROC curves; Classification; Classifiers ensemble; Detection of intestinal contractions; Imbalanced classes; Wireless capsule endoscopy
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Xavier Otazu, & Oriol Pujol. (2006). Wavelet based approach to cluster analysis. Application on low dimensional data sets. PRL - Pattern Recognition Letters, 27(14), 1590–1605.
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Debora Gil, & Petia Radeva. (2006). Inhibition of false landmarks. PRL - Pattern Recognition Letters, 27(9), 1022–1030.
Abstract: Corners and junctions are landmarks characterized by the lack of differentiability in the unit tangent to the image level curve. Detectors based on differential operators are not, by their own definition, the best posed as they require a higher degree of differentiability to yield a reliable response. We argue that a corner detector should be based on the degree of continuity of the tangent vector to the image level sets, work on the image domain and need no assumptions on neither the image local structure nor the particular geometry of the corner/junction. An operator measuring the degree of differentiability of the projection matrix on the image gradient fulfills the above requirements. Because using smoothing kernels leads to corner misplacement, we suggest an alternative fake response remover based on the receptive field inhibition of spurious details. The combination of both orientation discontinuity detection and noise inhibition produce our inhibition orientation energy (IOE) landmark locator.
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Debora Gil, Oriol Rodriguez-Leor, Petia Radeva, & J. Mauri. (2008). Myocardial Perfusion Characterization From Contrast Angiography Spectral Distribution. IEEE Transactions on Medical Imaging, 27(5), 641–649.
Abstract: Despite recovering a normal coronary flow after acute myocardial infarction, percutaneous coronary intervention does not guarantee a proper perfusion (irrigation) of the infarcted area. This damage in microcirculation integrity may detrimentally affect the patient survival. Visual assessment of the myocardium opacification in contrast angiography serves to define a subjective score of the microcirculation integrity myocardial blush analysis (MBA). Although MBA correlates with patient prognosis its visual assessment is a very difficult task that requires of a highly expertise training in order to achieve a good intraobserver and interobserver agreement. In this paper, we provide objective descriptors of the myocardium staining pattern by analyzing the spectrum of the image local statistics. The descriptors proposed discriminate among the different phenomena observed in the angiographic sequence and allow defining an objective score of the myocardial perfusion.
Keywords: Contrast angiography; myocardial perfusion; spectral analysis.
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R.A.Bendezu, E.Barba, E.Burri, D.Cisternas, Carolina Malagelada, Santiago Segui, et al. (2015). Intestinal gas content and distribution in health and in patients with functional gut symptoms. NEUMOT - Neurogastroenterology & Motility, 27(9), 1249–1257.
Abstract: BACKGROUND:
The precise relation of intestinal gas to symptoms, particularly abdominal bloating and distension remains incompletely elucidated. Our aim was to define the normal values of intestinal gas volume and distribution and to identify abnormalities in relation to functional-type symptoms.
METHODS:
Abdominal computed tomography scans were evaluated in healthy subjects (n = 37) and in patients in three conditions: basal (when they were feeling well; n = 88), during an episode of abdominal distension (n = 82) and after a challenge diet (n = 24). Intestinal gas content and distribution were measured by an original analysis program. Identification of patients outside the normal range was performed by machine learning techniques (one-class classifier). Results are expressed as median (IQR) or mean ± SE, as appropriate.
KEY RESULTS:
In healthy subjects the gut contained 95 (71, 141) mL gas distributed along the entire lumen. No differences were detected between patients studied under asymptomatic basal conditions and healthy subjects. However, either during a spontaneous bloating episode or once challenged with a flatulogenic diet, luminal gas was found to be increased and/or abnormally distributed in about one-fourth of the patients. These patients detected outside the normal range by the classifier exhibited a significantly greater number of abnormal features than those within the normal range (3.7 ± 0.4 vs 0.4 ± 0.1; p < 0.001).
CONCLUSIONS & INFERENCES:
The analysis of a large cohort of subjects using original techniques provides unique and heretofore unavailable information on the volume and distribution of intestinal gas in normal conditions and in relation to functional gastrointestinal symptoms.
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