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Oriol Pujol, & Petia Radeva. (2004). Texture Segmentation by Statistical Deformable Models. IJIG - International Journal of Image and Graphics, 433–452.
Abstract: Deformable models have received much popularity due to their ability to include high-level knowledge on the application domain into low-level image processing. Still, most proposed active contour models do not sufficiently profit from the application information and they are too generalized, leading to non-optimal final results of segmentation, tracking or 3D reconstruction processes. In this paper we propose a new deformable model defined in a statistical framework to segment objects of natural scenes. We perform a supervised learning of local appearance of the textured objects and construct a feature space using a set of co-occurrence matrix measures. Linear Discriminant Analysis allows us to obtain an optimal reduced feature space where a mixture model is applied to construct a likelihood map. Instead of using a heuristic potential field, our active model is deformed on a regularized version of the likelihood map in order to segment objects characterized by the same texture pattern. Different tests on synthetic images, natural scene and medical images show the advantages of our statistic deformable model.
Keywords: Texture segmentation, parametric active contours, statistic snakes
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Francesco Ciompi, Simone Balocco, Juan Rigla, Xavier Carrillo, Josefina Mauri, & Petia Radeva. (2016). Computer-Aided Detection of Intra-Coronary Stent in Intravascular Ultrasound Sequences. MP - Medical Physics, 43(10).
Abstract: Purpose: An intraluminal coronary stent is a metal mesh tube deployed in a stenotic artery during Percutaneous Coronary Intervention (PCI), in order to prevent acute vessel occlusion. The identi cation of struts location and the de nition of the stent shape are relevant for PCI planning 15 and for patient follow-up. We present a fully-automatic framework for Computer-Aided Detection
(CAD) of intra-coronary stents in Intravascular Ultrasound (IVUS) image sequences. The CAD system is able to detect stent struts and estimate the stent shape.
Methods: The proposed CAD uses machine learning to provide a comprehensive interpretation of the local structure of the vessel by means of semantic classi cation. The output of the classi cation 20 stage is then used to detect struts and to estimate the stent shape. The proposed approach is validated using a multi-centric data-set of 1,015 images from 107 IVUS sequences containing both metallic and bio-absorbable stents.
Results: The method was able to detect structs in both metallic stents with an overall F-measure of 77.7% and a mean distance of 0.15 mm from manually annotated struts, and in bio-absorbable 25 stents with an overall F-measure of 77.4% and a mean distance of 0.09 mm from manually annotated struts.
Conclusions: The results are close to the inter-observer variability and suggest that the system has the potential of being used as method for aiding percutaneous interventions.
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Simone Balocco, Carlo Gatta, Marina Alberti, Xavier Carrillo, Juan Rigla, & Petia Radeva. (2012). Relation between plaque type, plaque thickness, blood shear stress and plaque stress in coronary arteries assessed by X-ray Angiography and Intravascular Ultrasound. MEDPHYS - Medical Physics, 39(12), 7430–7445.
Abstract: PMID 23231293
PURPOSE:
Atheromatic plaque progression is affected, among others phenomena, by biomechanical, biochemical, and physiological factors. In this paper, the authors introduce a novel framework able to provide both morphological (vessel radius, plaque thickness, and type) and biomechanical (wall shear stress and Von Mises stress) indices of coronary arteries.
METHODS:
First, the approach reconstructs the three-dimensional morphology of the vessel from intravascular ultrasound (IVUS) and Angiographic sequences, requiring minimal user interaction. Then, a computational pipeline allows to automatically assess fluid-dynamic and mechanical indices. Ten coronary arteries are analyzed illustrating the capabilities of the tool and confirming previous technical and clinical observations.
RESULTS:
The relations between the arterial indices obtained by IVUS measurement and simulations have been quantitatively analyzed along the whole surface of the artery, extending the analysis of the coronary arteries shown in previous state of the art studies. Additionally, for the first time in the literature, the framework allows the computation of the membrane stresses using a simplified mechanical model of the arterial wall.
CONCLUSIONS:
Circumferentially (within a given frame), statistical analysis shows an inverse relation between the wall shear stress and the plaque thickness. At the global level (comparing a frame within the entire vessel), it is observed that heavy plaque accumulations are in general calcified and are located in the areas of the vessel having high wall shear stress. Finally, in their experiments the inverse proportionality between fluid and structural stresses is observed.
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R.A.Bendezu, E.Barba, E.Burri, D.Cisternas, Carolina Malagelada, Santiago Segui, et al. (2015). Intestinal gas content and distribution in health and in patients with functional gut symptoms. NEUMOT - Neurogastroenterology & Motility, 27(9), 1249–1257.
Abstract: BACKGROUND:
The precise relation of intestinal gas to symptoms, particularly abdominal bloating and distension remains incompletely elucidated. Our aim was to define the normal values of intestinal gas volume and distribution and to identify abnormalities in relation to functional-type symptoms.
METHODS:
Abdominal computed tomography scans were evaluated in healthy subjects (n = 37) and in patients in three conditions: basal (when they were feeling well; n = 88), during an episode of abdominal distension (n = 82) and after a challenge diet (n = 24). Intestinal gas content and distribution were measured by an original analysis program. Identification of patients outside the normal range was performed by machine learning techniques (one-class classifier). Results are expressed as median (IQR) or mean ± SE, as appropriate.
KEY RESULTS:
In healthy subjects the gut contained 95 (71, 141) mL gas distributed along the entire lumen. No differences were detected between patients studied under asymptomatic basal conditions and healthy subjects. However, either during a spontaneous bloating episode or once challenged with a flatulogenic diet, luminal gas was found to be increased and/or abnormally distributed in about one-fourth of the patients. These patients detected outside the normal range by the classifier exhibited a significantly greater number of abnormal features than those within the normal range (3.7 ± 0.4 vs 0.4 ± 0.1; p < 0.001).
CONCLUSIONS & INFERENCES:
The analysis of a large cohort of subjects using original techniques provides unique and heretofore unavailable information on the volume and distribution of intestinal gas in normal conditions and in relation to functional gastrointestinal symptoms.
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Sergio Escalera, Ana Puig, Oscar Amoros, & Maria Salamo. (2011). Intelligent GPGPU Classification in Volume Visualization: a framework based on Error-Correcting Output Codes. CGF - Computer Graphics Forum, 30(7), 2107–2115.
Abstract: IF JCR 1.455 2010 25/99
In volume visualization, the definition of the regions of interest is inherently an iterative trial-and-error process finding out the best parameters to classify and render the final image. Generally, the user requires a lot of expertise to analyze and edit these parameters through multi-dimensional transfer functions. In this paper, we present a framework of intelligent methods to label on-demand multiple regions of interest. These methods can be split into a two-level GPU-based labelling algorithm that computes in time of rendering a set of labelled structures using the Machine Learning Error-Correcting Output Codes (ECOC) framework. In a pre-processing step, ECOC trains a set of Adaboost binary classifiers from a reduced pre-labelled data set. Then, at the testing stage, each classifier is independently applied on the features of a set of unlabelled samples and combined to perform multi-class labelling. We also propose an alternative representation of these classifiers that allows to highly parallelize the testing stage. To exploit that parallelism we implemented the testing stage in GPU-OpenCL. The empirical results on different data sets for several volume structures shows high computational performance and classification accuracy.
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