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Simone Balocco, Carlo Gatta, Oriol Pujol, J. Mauri, & Petia Radeva. (2010). SRBF: Speckle Reducing Bilateral Filtering. UMB - Ultrasound in Medicine and Biology, 36(8), 1353–1363.
Abstract: Speckle noise negatively affects medical ultrasound image shape interpretation and boundary detection. Speckle removal filters are widely used to selectively remove speckle noise without destroying important image features to enhance object boundaries. In this article, a fully automatic bilateral filter tailored to ultrasound images is proposed. The edge preservation property is obtained by embedding noise statistics in the filter framework. Consequently, the filter is able to tackle the multiplicative behavior modulating the smoothing strength with respect to local statistics. The in silico experiments clearly showed that the speckle reducing bilateral filter (SRBF) has superior performances to most of the state of the art filtering methods. The filter is tested on 50 in vivo US images and its influence on a segmentation task is quantified. The results using SRBF filtered data sets show a superior performance to using oriented anisotropic diffusion filtered images. This improvement is due to the adaptive support of SRBF and the embedded noise statistics, yielding a more homogeneous smoothing. SRBF results in a fully automatic, fast and flexible algorithm potentially suitable in wide ranges of speckle noise sizes, for different medical applications (IVUS, B-mode, 3-D matrix array US).
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Frederic Sampedro, Anna Domenech, Sergio Escalera, & Ignasi Carrio. (2017). Computing quantitative indicators of structural renal damage in pediatric DMSA scans. REMNIM - Revista Española de Medicina Nuclear e Imagen Molecular, 36(2), 72–77.
Abstract: OBJECTIVES:
The proposal and implementation of a computational framework for the quantification of structural renal damage from 99mTc-dimercaptosuccinic acid (DMSA) scans. The aim of this work is to propose, implement, and validate a computational framework for the quantification of structural renal damage from DMSA scans and in an observer-independent manner.
MATERIALS AND METHODS:
From a set of 16 pediatric DMSA-positive scans and 16 matched controls and using both expert-guided and automatic approaches, a set of image-derived quantitative indicators was computed based on the relative size, intensity and histogram distribution of the lesion. A correlation analysis was conducted in order to investigate the association of these indicators with other clinical data of interest in this scenario, including C-reactive protein (CRP), white cell count, vesicoureteral reflux, fever, relative perfusion, and the presence of renal sequelae in a 6-month follow-up DMSA scan.
RESULTS:
A fully automatic lesion detection and segmentation system was able to successfully classify DMSA-positive from negative scans (AUC=0.92, sensitivity=81% and specificity=94%). The image-computed relative size of the lesion correlated with the presence of fever and CRP levels (p<0.05), and a measurement derived from the distribution histogram of the lesion obtained significant performance results in the detection of permanent renal damage (AUC=0.86, sensitivity=100% and specificity=75%).
CONCLUSIONS:
The proposal and implementation of a computational framework for the quantification of structural renal damage from DMSA scans showed a promising potential to complement visual diagnosis and non-imaging indicators.
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Meysam Madadi, Sergio Escalera, Jordi Gonzalez, Xavier Roca, & Felipe Lumbreras. (2015). Multi-part body segmentation based on depth maps for soft biometry analysis. PRL - Pattern Recognition Letters, 56, 14–21.
Abstract: This paper presents a novel method extracting biometric measures using depth sensors. Given a multi-part labeled training data, a new subject is aligned to the best model of the dataset, and soft biometrics such as lengths or circumference sizes of limbs and body are computed. The process is performed by training relevant pose clusters, defining a representative model, and fitting a 3D shape context descriptor within an iterative matching procedure. We show robust measures by applying orthogonal plates to body hull. We test our approach in a novel full-body RGB-Depth data set, showing accurate estimation of soft biometrics and better segmentation accuracy in comparison with random forest approach without requiring large training data.
Keywords: 3D shape context; 3D point cloud alignment; Depth maps; Human body segmentation; Soft biometry analysis
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Frederic Sampedro, Sergio Escalera, & Anna Puig. (2014). Iterative Multiclass Multiscale Stacked Sequential Learning: definition and application to medical volume segmentation. PRL - Pattern Recognition Letters, 46, 1–10.
Abstract: In this work we present the iterative multi-class multi-scale stacked sequential learning framework (IMMSSL), a novel learning scheme that is particularly suited for medical volume segmentation applications. This model exploits the inherent voxel contextual information of the structures of interest in order to improve its segmentation performance results. Without any feature set or learning algorithm prior assumption, the proposed scheme directly seeks to learn the contextual properties of a region from the predicted classifications of previous classifiers within an iterative scheme. Performance results regarding segmentation accuracy in three two-class and multi-class medical volume datasets show a significant improvement with respect to state of the art alternatives. Due to its easiness of implementation and its independence of feature space and learning algorithm, the presented machine learning framework could be taken into consideration as a first choice in complex volume segmentation scenarios.
Keywords: Machine learning; Sequential learning; Multi-class problems; Contextual learning; Medical volume segmentation
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Miguel Angel Bautista, Sergio Escalera, Xavier Baro, Petia Radeva, Jordi Vitria, & Oriol Pujol. (2011). Minimal Design of Error-Correcting Output Codes. PRL - Pattern Recognition Letters, 33(6), 693–702.
Abstract: IF JCR CCIA 1.303 2009 54/103
The classification of large number of object categories is a challenging trend in the pattern recognition field. In literature, this is often addressed using an ensemble of classifiers. In this scope, the Error-correcting output codes framework has demonstrated to be a powerful tool for combining classifiers. However, most state-of-the-art ECOC approaches use a linear or exponential number of classifiers, making the discrimination of a large number of classes unfeasible. In this paper, we explore and propose a minimal design of ECOC in terms of the number of classifiers. Evolutionary computation is used for tuning the parameters of the classifiers and looking for the best minimal ECOC code configuration. The results over several public UCI datasets and different multi-class computer vision problems show that the proposed methodology obtains comparable (even better) results than state-of-the-art ECOC methodologies with far less number of dichotomizers.
Keywords: Multi-class classification; Error-correcting output codes; Ensemble of classifiers
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