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Author Marta Diez-Ferrer; Arturo Morales; Rosa Lopez Lisbona; Noelia Cubero; Cristian Tebe; Susana Padrones; Samantha Aso; Jordi Dorca; Debora Gil; Antoni Rosell edit  url
openurl 
  Title Ultrathin Bronchoscopy with and without Virtual Bronchoscopic Navigation: Influence of Segmentation on Diagnostic Yield Type Journal Article
  Year 2019 Publication (up) Respiration Abbreviated Journal RES  
  Volume 97 Issue 3 Pages 252-258  
  Keywords Lung cancer; Peripheral lung lesion; Diagnosis; Bronchoscopy; Ultrathin bronchoscopy; Virtual bronchoscopic navigation  
  Abstract Background: Bronchoscopy is a safe technique for diagnosing peripheral pulmonary lesions (PPLs), and virtual bronchoscopic navigation (VBN) helps guide the bronchoscope to PPLs. Objectives: We aimed to compare the diagnostic yield of VBN-guided and unguided ultrathin bronchoscopy (UTB) and explore clinical and technical factors associated with better results. We developed a diagnostic algorithm for deciding whether to use VBN to reach PPLs or choose an alternative diagnostic approach. Methods: We compared diagnostic yield between VBN-UTB (prospective cases) and unguided UTB (historical controls) and analyzed the VBN-UTB subgroup to identify clinical and technical variables that could predict the success of VBN-UTB. Results: Fifty-five cases and 110 controls were included. The overall diagnostic yield did not differ between the VBN-guided and unguided arms (47 and 40%, respectively; p = 0.354). Although the yield was slightly higher for PPLs ≤20 mm in the VBN-UTB arm, the difference was not significant (p = 0.069). No other clinical characteristics were associated with a higher yield in a subgroup analysis, but an 85% diagnostic yield was observed when segmentation was optimal and the PPL was endobronchial (vs. 30% when segmentation was suboptimal and 20% when segmentation was optimal but the PPL was extrabronchial). Conclusions: VBN-guided UTB is not superior to unguided UTB. A greater impact of VBN-guided over unguided UTB is highly dependent on both segmentation quality and an endobronchial location of the PPL. Segmentation quality should be considered before starting a procedure, when an alternative technique that may improve yield can be chosen, saving time and resources.  
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  Notes IAM; 600.145; 600.139 Approved no  
  Call Number Admin @ si @ DML2019 Serial 3134  
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Author Marta Diez-Ferrer; Debora Gil; Cristian Tebe; Carles Sanchez edit   pdf
doi  openurl
  Title Positive Airway Pressure to Enhance Computed Tomography Imaging for Airway Segmentation for Virtual Bronchoscopic Navigation Type Journal Article
  Year 2018 Publication (up) Respiration Abbreviated Journal RES  
  Volume 96 Issue 6 Pages 525-534  
  Keywords Multidetector computed tomography; Bronchoscopy; Continuous positive airway pressure; Image enhancement; Virtual bronchoscopic navigation  
  Abstract Abstract
RATIONALE:
Virtual bronchoscopic navigation (VBN) guidance to peripheral pulmonary lesions is often limited by insufficient segmentation of the peripheral airways.

OBJECTIVES:
To test the effect of applying positive airway pressure (PAP) during CT acquisition to improve segmentation, particularly at end-expiration.

METHODS:
CT acquisitions in inspiration and expiration with 4 PAP protocols were recorded prospectively and compared to baseline inspiratory acquisitions in 20 patients. The 4 protocols explored differences between devices (flow vs. turbine), exposures (within seconds vs. 15-min) and pressure levels (10 vs. 14 cmH2O). Segmentation quality was evaluated with the number of airways and number of endpoints reached. A generalized mixed-effects model explored the estimated effect of each protocol.

MEASUREMENTS AND MAIN RESULTS:
Patient characteristics and lung function did not significantly differ between protocols. Compared to baseline inspiratory acquisitions, expiratory acquisitions after 15 min of 14 cmH2O PAP segmented 1.63-fold more airways (95% CI 1.07-2.48; p = 0.018) and reached 1.34-fold more endpoints (95% CI 1.08-1.66; p = 0.004). Inspiratory acquisitions performed immediately under 10 cmH2O PAP reached 1.20-fold (95% CI 1.09-1.33; p < 0.001) more endpoints; after 15 min the increase was 1.14-fold (95% CI 1.05-1.24; p < 0.001).

CONCLUSIONS:
CT acquisitions with PAP segment more airways and reach more endpoints than baseline inspiratory acquisitions. The improvement is particularly evident at end-expiration after 15 min of 14 cmH2O PAP. Further studies must confirm that the improvement increases diagnostic yield when using VBN to evaluate peripheral pulmonary lesions.		  
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  Notes IAM; 600.145 Approved no  
  Call Number Admin @ si @ DGT2018 Serial 3135  
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Author Oriol Rodriguez-Leon.A.Carol;H.Tizon; Eduard Fernandez-Nofrerias; Josefina Mauri; Vicente del Valle; Debora Gil; Aura Hernandez-Sabate; Petia Radeva edit  openurl
  Title Model estadístic-determinístic per la segmentació de l adventicia en imatges d ecografía intracoronaria Type Journal Article
  Year 2005 Publication (up) Rev Societat Catalana Cardiologia Abbreviated Journal  
  Volume 5 Issue Pages 41  
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  Notes IAM;MILAB Approved no  
  Call Number IAM @ iam @ RCT2005 Serial 1637  
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Author Mireia Sole; Joan Blanco; Debora Gil; G. Fonseka; Richard Frodsham; Oliver Valero; Francesca Vidal; Zaida Sarrate edit  openurl
  Title Análisis 3d de la territorialidad cromosómica en células espermatogénicas: explorando la infertilidad desde un nuevo prisma Type Journal
  Year 2017 Publication (up) Revista Asociación para el Estudio de la Biología de la Reproducción Abbreviated Journal ASEBIR  
  Volume 22 Issue 2 Pages 105  
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  Notes IAM; 600.096; 600.145 Approved no  
  Call Number Admin @ si @ SBG2017d Serial 3042  
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Author Oriol Rodriguez-Leon; Josefina Mauri;Eduard Fernandez-Nofrerias; Antonio Tovar; Vicente del Valle; Aura Hernandez-Sabate; Debora Gil; Petia Radeva edit  openurl
  Title Utilizacion de la estructura de los campos vectoriales para la deteccion de la Adventicia en imagenes de Ecografia Intracoronaria Type Journal
  Year 2004 Publication (up) Revista Española de Cardiología Abbreviated Journal REC  
  Volume 57 Issue 2 Pages 100  
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  Notes MILAB;IAM Approved no  
  Call Number BCNPCL @ bcnpcl @ RMF2004 Serial 566  
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