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O. Rodriguez, J. Mauri, E Fernandez-Nofrerias, A. Tovar, R. Villuendas, V. Valle, et al. (2003). Analisis de texturas mediante la modificacion de un modelo binario local para la segmentacion automatica de secuencias de ecografia intracoronaria. Revista Española de Cardiologia (IF: 0.959), 56(2), Congreso de las Enfermedades Cardiovasculares.
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O. Rodriguez, J. Mauri, E Fernandez-Nofrerias, J. Lopez, A. Tovar, V. Valle, et al. (2003). Cuantificacion tridimensional de la longitud de segmentos coronarios a partir de secuencias de ecografia intracoronaria. Revista Española de Cardiologia (IF: 0.959), 56(2), Congreso de las Enfermedades Cardiovasculares.
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O. Rodriguez, J. Mauri, E Fernandez-Nofrerias, J. Lopez, A. Tovar, R. Villuendas, et al. (2003). Modelo fisico para la simulacion de imagenes de ecografia intracoronaria. Revista Española de Cardiologia (IF: 0.959), 56(2), Congreso de las Enfermedades Cardiovasculares.
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Frederic Sampedro, Anna Domenech, Sergio Escalera, & Ignasi Carrio. (2017). Computing quantitative indicators of structural renal damage in pediatric DMSA scans. REMNIM - Revista Española de Medicina Nuclear e Imagen Molecular, 36(2), 72–77.
Abstract: OBJECTIVES:
The proposal and implementation of a computational framework for the quantification of structural renal damage from 99mTc-dimercaptosuccinic acid (DMSA) scans. The aim of this work is to propose, implement, and validate a computational framework for the quantification of structural renal damage from DMSA scans and in an observer-independent manner.
MATERIALS AND METHODS:
From a set of 16 pediatric DMSA-positive scans and 16 matched controls and using both expert-guided and automatic approaches, a set of image-derived quantitative indicators was computed based on the relative size, intensity and histogram distribution of the lesion. A correlation analysis was conducted in order to investigate the association of these indicators with other clinical data of interest in this scenario, including C-reactive protein (CRP), white cell count, vesicoureteral reflux, fever, relative perfusion, and the presence of renal sequelae in a 6-month follow-up DMSA scan.
RESULTS:
A fully automatic lesion detection and segmentation system was able to successfully classify DMSA-positive from negative scans (AUC=0.92, sensitivity=81% and specificity=94%). The image-computed relative size of the lesion correlated with the presence of fever and CRP levels (p<0.05), and a measurement derived from the distribution histogram of the lesion obtained significant performance results in the detection of permanent renal damage (AUC=0.86, sensitivity=100% and specificity=75%).
CONCLUSIONS:
The proposal and implementation of a computational framework for the quantification of structural renal damage from DMSA scans showed a promising potential to complement visual diagnosis and non-imaging indicators.
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Oriol Rodriguez-Leon, Josefina Mauri, Eduard Fernandez-Nofrerias, Antonio Tovar, Vicente del Valle, Aura Hernandez-Sabate, et al. (2004). Utilización de la Estructura de los Campos Vectoriales para la Detección de la Adventicia en Imágenes de Ecografía Intracoronaria. Revista Internacional de Enfermedades Cardiovasculares Revista Española de Cardiología, 57(2), 100.
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