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Ana Garcia Rodriguez, Yael Tudela, Henry Cordova, S. Carballal, I. Ordas, L. Moreira, et al. (2022). First in Vivo Computer-Aided Diagnosis of Colorectal Polyps using White Light Endoscopy. END - Endoscopy, 54.
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O.F.Ahmad, Y.Mori, M.Misawa, S.Kudo, J.T.Anderson, & Jorge Bernal. (2021). Establishing key research questions for the implementation of artificial intelligence in colonoscopy: a modified Delphi method. END - Endoscopy, 53(9), 893–901.
Abstract: BACKGROUND : Artificial intelligence (AI) research in colonoscopy is progressing rapidly but widespread clinical implementation is not yet a reality. We aimed to identify the top implementation research priorities. METHODS : An established modified Delphi approach for research priority setting was used. Fifteen international experts, including endoscopists and translational computer scientists/engineers, from nine countries participated in an online survey over 9 months. Questions related to AI implementation in colonoscopy were generated as a long-list in the first round, and then scored in two subsequent rounds to identify the top 10 research questions. RESULTS : The top 10 ranked questions were categorized into five themes. Theme 1: clinical trial design/end points (4 questions), related to optimum trial designs for polyp detection and characterization, determining the optimal end points for evaluation of AI, and demonstrating impact on interval cancer rates. Theme 2: technological developments (3 questions), including improving detection of more challenging and advanced lesions, reduction of false-positive rates, and minimizing latency. Theme 3: clinical adoption/integration (1 question), concerning the effective combination of detection and characterization into one workflow. Theme 4: data access/annotation (1 question), concerning more efficient or automated data annotation methods to reduce the burden on human experts. Theme 5: regulatory approval (1 question), related to making regulatory approval processes more efficient. CONCLUSIONS : This is the first reported international research priority setting exercise for AI in colonoscopy. The study findings should be used as a framework to guide future research with key stakeholders to accelerate the clinical implementation of AI in endoscopy.
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Ana Garcia Rodriguez, Yael Tudela, Henry Cordova, S. Carballal, I. Ordas, L. Moreira, et al. (2022). In vivo computer-aided diagnosis of colorectal polyps using white light endoscopy. ENDIO - Endoscopy International Open, 10(9), E1201–E1207.
Abstract: Background and study aims Artificial intelligence is currently able to accurately predict the histology of colorectal polyps. However, systems developed to date use complex optical technologies and have not been tested in vivo. The objective of this study was to evaluate the efficacy of a new deep learning-based optical diagnosis system, ATENEA, in a real clinical setting using only high-definition white light endoscopy (WLE) and to compare its performance with endoscopists. Methods ATENEA was prospectively tested in real life on consecutive polyps detected in colorectal cancer screening colonoscopies at Hospital Clínic. No images were discarded, and only WLE was used. The in vivo ATENEA's prediction (adenoma vs non-adenoma) was compared with the prediction of four staff endoscopists without specific training in optical diagnosis for the study purposes. Endoscopists were blind to the ATENEA output. Histology was the gold standard. Results Ninety polyps (median size: 5 mm, range: 2-25) from 31 patients were included of which 69 (76.7 %) were adenomas. ATENEA correctly predicted the histology in 63 of 69 (91.3 %, 95 % CI: 82 %-97 %) adenomas and 12 of 21 (57.1 %, 95 % CI: 34 %-78 %) non-adenomas while endoscopists made correct predictions in 52 of 69 (75.4 %, 95 % CI: 60 %-85 %) and 20 of 21 (95.2 %, 95 % CI: 76 %-100 %), respectively. The global accuracy was 83.3 % (95 % CI: 74%-90 %) and 80 % (95 % CI: 70 %-88 %) for ATENEA and endoscopists, respectively. Conclusion ATENEA can accurately be used for in vivo characterization of colorectal polyps, enabling the endoscopist to make direct decisions. ATENEA showed a global accuracy similar to that of endoscopists despite an unsatisfactory performance for non-adenomatous lesions.
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Mikhail Mozerov, Ignasi Rius, Xavier Roca, & Jordi Gonzalez. (2010). Nonlinear synchronization for automatic learning of 3D pose variability in human motion sequences. EURASIPJ - EURASIP Journal on Advances in Signal Processing, .
Abstract: Article ID 507247
A dense matching algorithm that solves the problem of synchronizing prerecorded human motion sequences, which show different speeds and accelerations, is proposed. The approach is based on minimization of MRF energy and solves the problem by using Dynamic Programming. Additionally, an optimal sequence is automatically selected from the input dataset to be a time-scale pattern for all other sequences. The paper utilizes an action specific model which automatically learns the variability of 3D human postures observed in a set of training sequences. The model is trained using the public CMU motion capture dataset for the walking action, and a mean walking performance is automatically learnt. Additionally, statistics about the observed variability of the postures and motion direction are also computed at each time step. The synchronized motion sequences are used to learn a model of human motion for action recognition and full-body tracking purposes.
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Ariel Amato, Mikhail Mozerov, Xavier Roca, & Jordi Gonzalez. (2010). Robust Real-Time Background Subtraction Based on Local Neighborhood Patterns. EURASIPJ - EURASIP Journal on Advances in Signal Processing, , 7.
Abstract: Article ID 901205
This paper describes an efficient background subtraction technique for detecting moving objects. The proposed approach is able to overcome difficulties like illumination changes and moving shadows. Our method introduces two discriminative features based on angular and modular patterns, which are formed by similarity measurement between two sets of RGB color vectors: one belonging to the background image and the other to the current image. We show how these patterns are used to improve foreground detection in the presence of moving shadows and in the case when there are strong similarities in color between background and foreground pixels. Experimental results over a collection of public and own datasets of real image sequences demonstrate that the proposed technique achieves a superior performance compared with state-of-the-art methods. Furthermore, both the low computational and space complexities make the presented algorithm feasible for real-time applications.
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