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Maria Oliver, G. Haro, Mariella Dimiccoli, B. Mazin, & C. Ballester. (2016). A Computational Model for Amodal Completion. JMIV - Journal of Mathematical Imaging and Vision, 56(3), 511–534.
Abstract: This paper presents a computational model to recover the most likely interpretation
of the 3D scene structure from a planar image, where some objects may occlude others. The estimated scene interpretation is obtained by integrating some global and local cues and provides both the complete disoccluded objects that form the scene and their ordering according to depth.
Our method first computes several distal scenes which are compatible with the proximal planar image. To compute these different hypothesized scenes, we propose a perceptually inspired object disocclusion method, which works by minimizing the Euler's elastica as well as by incorporating the relatability of partially occluded contours and the convexity of the disoccluded objects. Then, to estimate the preferred scene we rely on a Bayesian model and define probabilities taking into account the global complexity of the objects in the hypothesized scenes as well as the effort of bringing these objects in their relative position in the planar image, which is also measured by an Euler's elastica-based quantity. The model is illustrated with numerical experiments on, both, synthetic and real images showing the ability of our model to reconstruct the occluded objects and the preferred perceptual order among them. We also present results on images of the Berkeley dataset with provided figure-ground ground-truth labeling.
Keywords: Perception; visual completion; disocclusion; Bayesian model;relatability; Euler elastica
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Frederic Sampedro, Sergio Escalera, Anna Domenech, & Ignasi Carrio. (2015). Automatic Tumor Volume Segmentation in Whole-Body PET/CT Scans: A Supervised Learning Approach Source. JMIHI - Journal of Medical Imaging and Health Informatics, 5(2), 192–201.
Abstract: Whole-body 3D PET/CT tumoral volume segmentation provides relevant diagnostic and prognostic information in clinical oncology and nuclear medicine. Carrying out this procedure manually by a medical expert is time consuming and suffers from inter- and intra-observer variabilities. In this paper, a completely automatic approach to this task is presented. First, the problem is stated and described both in clinical and technological terms. Then, a novel supervised learning segmentation framework is introduced. The segmentation by learning approach is defined within a Cascade of Adaboost classifiers and a 3D contextual proposal of Multiscale Stacked Sequential Learning. Segmentation accuracy results on 200 Breast Cancer whole body PET/CT volumes show mean 49% sensitivity, 99.993% specificity and 39% Jaccard overlap Index, which represent good performance results both at the clinical and technological level.
Keywords: CONTEXTUAL CLASSIFICATION; PET/CT; SUPERVISED LEARNING; TUMOR SEGMENTATION; WHOLE BODY
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Frederic Sampedro, Anna Domenech, & Sergio Escalera. (2014). Static and dynamic computational cancer spread quantification in whole body FDG-PET/CT scans. JMIHI - Journal of Medical Imaging and Health Informatics, 4(6), 825–831.
Abstract: In this work we address the computational cancer spread quantification scenario in whole body FDG-PET/CT scans. At the static level, this setting can be modeled as a clustering problem on the set of 3D connected components of the whole body PET tumoral segmentation mask carried out by nuclear medicine physicians. At the dynamic level, and ad-hoc algorithm is proposed in order to quantify the cancer spread time evolution which, when combined with other existing indicators, gives rise to the metabolic tumor volume-aggressiveness-spread time evolution chart, a novel tool that we claim that would prove useful in nuclear medicine and oncological clinical or research scenarios. Good performance results of the proposed methodologies both at the clinical and technological level are shown using a dataset of 48 segmented whole body FDG-PET/CT scans.
Keywords: CANCER SPREAD; COMPUTER AIDED DIAGNOSIS; MEDICAL IMAGING; TUMOR QUANTIFICATION
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Tadashi Araki, Sumit K. Banchhor, Narendra D. Londhe, Nobutaka Ikeda, Petia Radeva, Devarshi Shukla, et al. (2016). Reliable and Accurate Calcium Volume Measurement in Coronary Artery Using Intravascular Ultrasound Videos. JMS - Journal of Medical Systems, 40(3), 51:1–51:20.
Abstract: Quantitative assessment of calcified atherosclerotic volume within the coronary artery wall is vital for cardiac interventional procedures. The goal of this study is to automatically measure the calcium volume, given the borders of coronary vessel wall for all the frames of the intravascular ultrasound (IVUS) video. Three soft computing fuzzy classification techniques were adapted namely Fuzzy c-Means (FCM), K-means, and Hidden Markov Random Field (HMRF) for automated segmentation of calcium regions and volume computation. These methods were benchmarked against previously developed threshold-based method. IVUS image data sets (around 30,600 IVUS frames) from 15 patients were collected using 40 MHz IVUS catheter (Atlantis® SR Pro, Boston Scientific®, pullback speed of 0.5 mm/s). Calcium mean volume for FCM, K-means, HMRF and threshold-based method were 37.84 ± 17.38 mm3, 27.79 ± 10.94 mm3, 46.44 ± 19.13 mm3 and 35.92 ± 16.44 mm3 respectively. Cross-correlation, Jaccard Index and Dice Similarity were highest between FCM and threshold-based method: 0.99, 0.92 ± 0.02 and 0.95 + 0.02 respectively. Student’s t-test, z-test and Wilcoxon-test are also performed to demonstrate consistency, reliability and accuracy of the results. Given the vessel wall region, the system reliably and automatically measures the calcium volume in IVUS videos. Further, we validated our system against a trained expert using scoring: K-means showed the best performance with an accuracy of 92.80 %. Out procedure and protocol is along the line with method previously published clinically.
Keywords: Interventional cardiology; Atherosclerosis; Coronary arteries; IVUS; calcium volume; Soft computing; Performance Reliability; Accuracy
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Sergio Escalera, Oriol Pujol, J. Mauri, & Petia Radeva. (2009). Intravascular Ultrasound Tissue Characterization with Sub-class Error-Correcting Output Codes. Journal of Signal Processing Systems, 55(1-3), 35–47.
Abstract: Intravascular ultrasound (IVUS) represents a powerful imaging technique to explore coronary vessels and to study their morphology and histologic properties. In this paper, we characterize different tissues based on radial frequency, texture-based, and combined features. To deal with the classification of multiple tissues, we require the use of robust multi-class learning techniques. In this sense, error-correcting output codes (ECOC) show to robustly combine binary classifiers to solve multi-class problems. In this context, we propose a strategy to model multi-class classification tasks using sub-classes information in the ECOC framework. The new strategy splits the classes into different sub-sets according to the applied base classifier. Complex IVUS data sets containing overlapping data are learnt by splitting the original set of classes into sub-classes, and embedding the binary problems in a problem-dependent ECOC design. The method automatically characterizes different tissues, showing performance improvements over the state-of-the-art ECOC techniques for different base classifiers. Furthermore, the combination of RF and texture-based features also shows improvements over the state-of-the-art approaches.
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