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Debora Gil, Oriol Rodriguez-Leor, Petia Radeva, & J. Mauri. (2008). Myocardial Perfusion Characterization From Contrast Angiography Spectral Distribution. IEEE Transactions on Medical Imaging, 27(5), 641–649.
Abstract: Despite recovering a normal coronary flow after acute myocardial infarction, percutaneous coronary intervention does not guarantee a proper perfusion (irrigation) of the infarcted area. This damage in microcirculation integrity may detrimentally affect the patient survival. Visual assessment of the myocardium opacification in contrast angiography serves to define a subjective score of the microcirculation integrity myocardial blush analysis (MBA). Although MBA correlates with patient prognosis its visual assessment is a very difficult task that requires of a highly expertise training in order to achieve a good intraobserver and interobserver agreement. In this paper, we provide objective descriptors of the myocardium staining pattern by analyzing the spectrum of the image local statistics. The descriptors proposed discriminate among the different phenomena observed in the angiographic sequence and allow defining an objective score of the myocardial perfusion.
Keywords: Contrast angiography; myocardial perfusion; spectral analysis.
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Oriol Rodriguez-Leor, A. Carol, H. Tizon, Eduard Fernandez-Nofrerias, J. Mauri, Vicente del Valle, et al. (2005). Model estadístic-determinístic per la segmentació de l adventicia en imatges d ecografía intracoronaria. Rev Societat Catalana Cardiologia, 5, 41.
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Oriol Rodriguez-Leor, J. Mauri, Eduard Fernandez-Nofrerias, C. Garcia, R. Villuendas, Vicente del Valle, et al. (2003). Reconstruction of a spatio-temporal model of the intima layer from intravascular ultrasound sequences. European Heart Journal, .
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Oriol Rodriguez-Leor, J. Mauri, Eduard Fernandez-Nofrerias, Antonio Tovar, Vicente del Valle, Aura Hernandez-Sabate, et al. (2004). Utilización de la Estructura de los Campos Vectoriales para la Detección de la Adventicia en Imágenes de Ecografía Intracoronaria. Revista Internacional de Enfermedades Cardiovasculares Revista Española de Cardiología, 57(2), 100.
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Misael Rosales, Petia Radeva, Oriol Rodriguez-Leor, & Debora Gil. (2009). Modelling of image-catheter motion for 3-D IVUS. MIA - Medical image analysis, 13(1), 91–104.
Abstract: Three-dimensional intravascular ultrasound (IVUS) allows to visualize and obtain volumetric measurements of coronary lesions through an exploration of the cross sections and longitudinal views of arteries. However, the visualization and subsequent morpho-geometric measurements in IVUS longitudinal cuts are subject to distortion caused by periodic image/vessel motion around the IVUS catheter. Usually, to overcome the image motion artifact ECG-gating and image-gated approaches are proposed, leading to slowing the pullback acquisition or disregarding part of IVUS data. In this paper, we argue that the image motion is due to 3-D vessel geometry as well as cardiac dynamics, and propose a dynamic model based on the tracking of an elliptical vessel approximation to recover the rigid transformation and align IVUS images without loosing any IVUS data. We report an extensive validation with synthetic simulated data and in vivo IVUS sequences of 30 patients achieving an average reduction of the image artifact of 97% in synthetic data and 79% in real-data. Our study shows that IVUS alignment improves longitudinal analysis of the IVUS data and is a necessary step towards accurate reconstruction and volumetric measurements of 3-D IVUS.
Keywords: Intravascular ultrasound (IVUS); Motion estimation; Motion decomposition; Fourier
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